PEGylation as a strategy for improving nanoparticle-based drug and gene delivery JS Suk, Q Xu, N Kim, J Hanes, LM Ensign Advanced drug delivery reviews 99, 28-51, 2016 | 3538 | 2016 |
Mucus-penetrating nanoparticles for drug and gene delivery to mucosal tissues SK Lai, YY Wang, J Hanes Advanced drug delivery reviews 61 (2), 158-171, 2009 | 1966 | 2009 |
Oral drug delivery with polymeric nanoparticles: the gastrointestinal mucus barriers LM Ensign, R Cone, J Hanes Advanced drug delivery reviews 64 (6), 557-570, 2012 | 1581 | 2012 |
Large porous particles for pulmonary drug delivery DA Edwards, J Hanes, G Caponetti, J Hrkach, A Ben-Jebria, ML Eskew, ... Science 276 (5320), 1868-1872, 1997 | 1540 | 1997 |
Micro-and macrorheology of mucus SK Lai, YY Wang, D Wirtz, J Hanes Advanced drug delivery reviews 61 (2), 86-100, 2009 | 1271 | 2009 |
Rapid transport of large polymeric nanoparticles in fresh undiluted human mucus SK Lai, DE O'Hanlon, S Harrold, ST Man, YY Wang, R Cone, J Hanes Proceedings of the National Academy of Sciences 104 (5), 1482-1487, 2007 | 1200 | 2007 |
Particles incorporating surfactants for pulmonary drug delivery J Hanes, DA Edwards, C Evora, R Langer US Patent 5,855,913, 1999 | 692 | 1999 |
Addressing the PEG mucoadhesivity paradox to engineer nanoparticles that “slip” through the human mucus barrier YY Wang, SK Lai, JS Suk, A Pace, R Cone, J Hanes Angewandte Chemie (International ed. in English) 47 (50), 9726, 2008 | 681 | 2008 |
A dense poly (ethylene glycol) coating improves penetration of large polymeric nanoparticles within brain tissue EA Nance, GF Woodworth, KA Sailor, TY Shih, Q Xu, G Swaminathan, ... Science translational medicine 4 (149), 149ra119-149ra119, 2012 | 652 | 2012 |
Aerodynamically light particles for pulmonary drug delivery DA Edwards, G Caponetti, JS Hrkach, N Lotan, J Hanes, AA Ben-Jebria, ... US Patent 5,874,064, 1999 | 629 | 1999 |
Biodegradable polymer nanoparticles that rapidly penetrate the human mucus barrier BC Tang, M Dawson, SK Lai, YY Wang, JS Suk, M Yang, P Zeitlin, ... Proceedings of the National Academy of Sciences 106 (46), 19268-19273, 2009 | 528 | 2009 |
A theoretical model of erosion and macromolecular drug release from biodegrading microspheres RP Batycky, J Hanes, R Langer, DA Edwards Journal of pharmaceutical sciences 86 (12), 1464-1477, 1997 | 510 | 1997 |
Impact of Surface Polyethylene Glycol (PEG) Density on Biodegradable Nanoparticle Transport in Mucus ex Vivo and Distribution in Vivo Q Xu, LM Ensign, NJ Boylan, A Schon, X Gong, JC Yang, NW Lamb, ... ACS nano 9 (9), 9217-9227, 2015 | 504 | 2015 |
Efficient active transport of gene nanocarriers to the cell nucleus J Suh, D Wirtz, J Hanes Proceedings of the National Academy of Sciences 100 (7), 3878-3882, 2003 | 503 | 2003 |
Nanoparticle diffusion in respiratory mucus from humans without lung disease BS Schuster, JS Suk, GF Woodworth, J Hanes Biomaterials 34 (13), 3439-3446, 2013 | 433 | 2013 |
Nanoparticles reveal that human cervicovaginal mucus is riddled with pores larger than viruses SK Lai, YY Wang, K Hida, R Cone, J Hanes Proceedings of the National Academy of Sciences 107 (2), 598-603, 2010 | 429 | 2010 |
Nanoparticles for oral delivery: Design, evaluation and state-of-the-art AA Date, J Hanes, LM Ensign Journal of Controlled Release 240, 504-526, 2016 | 420 | 2016 |
Enhanced viscoelasticity of human cystic fibrotic sputum correlates with increasing microheterogeneity in particle transport M Dawson, D Wirtz, J Hanes Journal of Biological Chemistry 278 (50), 50393-50401, 2003 | 374 | 2003 |
Mucus-penetrating nanoparticles for vaginal drug delivery protect against herpes simplex virus LM Ensign, BC Tang, YY Wang, TA Tse, T Hoen, R Cone, J Hanes Science translational medicine 4 (138), 138ra79-138ra79, 2012 | 367 | 2012 |
The penetration of fresh undiluted sputum expectorated by cystic fibrosis patients by non-adhesive polymer nanoparticles JS Suk, SK Lai, YY Wang, LM Ensign, PL Zeitlin, MP Boyle, J Hanes Biomaterials 30 (13), 2591-2597, 2009 | 365 | 2009 |