| Internal duplication and homology with bacterial transport proteins in the< i> mdr</i> 1 (P-glycoprotein) gene from multidrug-resistant human cells C Chen, JE Chin, K Ueda, DP Clark, I Pastan, MM Gottesman, ... Cell 47 (3), 381-389, 1986 | 2573 | 1986 |
| Quantitative analysis of MDR1 (multidrug resistance) gene expression in human tumors by polymerase chain reaction. KE Noonan, C Beck, TA Holzmayer, JE Chin, JS Wunder, IL Andrulis, ... Proceedings of the National Academy of Sciences 87 (18), 7160-7164, 1990 | 1059 | 1990 |
| Isolation of human mdr DNA sequences amplified in multidrug-resistant KB carcinoma cells IB Roninson, JE Chin, KG Choi, P Gros, DE Housman, A Fojo, DW Shen, ... Proceedings of the National Academy of Sciences 83 (12), 4538-4542, 1986 | 922 | 1986 |
| Human multidrug-resistant cell lines: increased mdr1 expression can precede gene amplification DW Shen, A Fojo, JE Chin, IB Roninson, N Richert, I Pastan, ... Science 232 (4750), 643-645, 1986 | 754 | 1986 |
| Structure and expression of the human MDR (P-glycoprotein) gene family. JE Chin, R Soffir, KE Noonan, K Choi, IB Roninson Molecular and cellular biology 9 (9), 3808-3820, 1989 | 406 | 1989 |
| Overexpression of protein kinase C isoenzymes alpha, beta I, gamma, and epsilon in cells overexpressing the insulin receptor. Effects on receptor phosphorylation and signaling. JE Chin, M Dickens, JM Tavare, RA Roth Journal of Biological Chemistry 268 (9), 6338-6347, 1993 | 215 | 1993 |
| Multidrug resistance of DNA-mediated transformants is linked to transfer of the human mdr1 gene. DW Shen, A Fojo, IB Roninson, JE Chin, R Soffir, I Pastan, MM Gottesman Molecular and cellular biology 6 (11), 4039-4045, 1986 | 195 | 1986 |
| Activation of protein kinase C alpha inhibits insulin-stimulated tyrosine phosphorylation of insulin receptor substrate-1. JE Chin, F Liu, RA Roth Molecular Endocrinology 8 (1), 51-58, 1994 | 143 | 1994 |
| Localization of multidrug resistance-associated DNA sequences to human chromosome 7 A Fojo, R Lebo, N Shimizu, JE Chin, IB Roninson, GT Merlino, ... Somatic cell and molecular genetics 12 (4), 415-420, 1986 | 128 | 1986 |
| DNA polymorphism of the C4 genes: a new marker for analysis of the major histocompatibility complex AS Whitehead, DE Woods, E Fleischnick, JE Chin, EJ Yunis, AJ Katz, ... New England Journal of Medicine 310 (2), 88-91, 1984 | 94 | 1984 |
| Effects of skyrin, a receptor-selective glucagon antagonist, in rat and human hepatocytes. JC Parker, RK McPherson, KM Andrews, CB Levy, JS Dubins, JE Chin, ... Diabetes 49 (12), 2079-2086, 2000 | 83 | 2000 |
| Biochemical mechanisms of insulin resistance RA Roth, F Liu, JE Chin Hormone Research in Paediatrics 41 (Suppl. 2), 51-55, 1994 | 57 | 1994 |
| Identification of Tetrahydropyrido [4, 3-d] pyrimidine Amides as a New Class of Orally Bioavailable TGR5 Agonists DW Piotrowski, K Futatsugi, JS Warmus, STM Orr, KD Freeman-Cook, ... ACS Medicinal Chemistry Letters 4 (1), 63-68, 2012 | 49 | 2012 |
| Characterization of insulin-stimulated protein serine/threonine kinases in CHO cells expressing human insulin receptors with point and deletion mutations. M Dickens, JE Chin, RA Roth, L Ellis, RM Denton, JM Tavaré Biochem. J 287, 201-209, 1992 | 48 | 1992 |
| Tavare!, JM (1992) Characterization of insulin-stimulated protein serine/threonine kinases in CHO cells expressing human insulin receptors with point and deletion mutations M Dickens, JE Chin, RA Roth, L Ellis, RM Denton Biochem. J 287, 201-209, 0 | 48* | |
| Evidence for hybrid rodent and human insulin receptors in transfected cells. JE Chin, JM Tavare, L Ellis, RA Roth Journal of Biological Chemistry 266 (24), 15587-15590, 1991 | 47 | 1991 |
| Substrates and signalling complexes: the tortured path to insulin action RA Roth, B Zhang, JE Chin, K Kovacina Journal of cellular biochemistry 48 (1), 12-18, 1992 | 41 | 1992 |
| Optimization of triazole-based TGR5 agonists towards orally available agents K Futatsugi, KB Bahnck, MB Brenner, J Buxton, JE Chin, SB Coffey, ... MedChemComm 4 (1), 205-210, 2013 | 30 | 2013 |
| Discovery of 5-phenoxy-1, 3-dimethyl-1< i> H</i>-pyrazole-4-carboxamides as potent agonists of TGR5 via sequential combinatorial libraries AT Londregan, DW Piotrowski, K Futatsugi, JS Warmus, M Boehm, ... Bioorganic & medicinal chemistry letters 23 (5), 1407-1411, 2013 | 27 | 2013 |
| Discovery of< i> N</i>-benzyl-2-[(4< i> S</i>)-4-(1< i> H</i>-indol-3-ylmethyl)-5-oxo-1-phenyl-4, 5-dihydro-6< i> H</i>-[1, 2, 4] triazolo [4, 3-< i> a</i>][1, 5] benzodiazepin … RL Elliott, KO Cameron, JE Chin, JA Bartlett, EE Beretta, Y Chen, ... Bioorganic & medicinal chemistry letters 20 (22), 6797-6801, 2010 | 27 | 2010 |
