Cell fate decisions are specified by the dynamic ERK interactome A Von Kriegsheim, D Baiocchi, M Birtwistle, D Sumpton, W Bienvenut, ... Nature cell biology 11 (12), 1458-1464, 2009 | 348 | 2009 |
Improving the metabolic fidelity of cancer models with a physiological cell culture medium J Vande Voorde, T Ackermann, N Pfetzer, D Sumpton, G Mackay, G Kalna, ... Science advances 5 (1), eaau7314, 2019 | 321 | 2019 |
Blebs produced by actin–myosin contraction during apoptosis release damage-associated molecular pattern proteins before secondary necrosis occurs GR Wickman, L Julian, K Mardilovich, S Schumacher, J Munro, N Rath, ... Cell Death & Differentiation 20 (10), 1293-1305, 2013 | 223 | 2013 |
Comparative large scale characterization of plant versus mammal proteins reveals similar and idiosyncratic N-α-acetylation features WV Bienvenut, D Sumpton, A Martinez, S Lilla, C Espagne, T Meinnel, ... Molecular & cellular proteomics 11 (6), 2012 | 188 | 2012 |
Motif affinity and mass spectrometry proteomic approach for the discovery of cellular AMPK targets: identification of mitochondrial fission factor as a new AMPK substrate S Ducommun, M Deak, D Sumpton, RJ Ford, AN Galindo, M Kussmann, ... Cellular signalling 27 (5), 978-988, 2015 | 181 | 2015 |
The amino acid transporter SLC7A5 is required for efficient growth of KRAS-mutant colorectal cancer AK Najumudeen, F Ceteci, SK Fey, G Hamm, RT Steven, H Hall, ... Nature genetics 53 (1), 16-26, 2021 | 148 | 2021 |
D-mannose suppresses macrophage IL-1β production S Torretta, A Scagliola, L Ricci, F Mainini, S Di Marco, I Cuccovillo, ... Nature communications 11 (1), 6343, 2020 | 147 | 2020 |
2, 4-dienoyl-CoA reductase regulates lipid homeostasis in treatment-resistant prostate cancer A Blomme, CA Ford, E Mui, R Patel, C Ntala, LE Jamieson, M Planque, ... Nature Communications 11 (1), 2508, 2020 | 132 | 2020 |
Mutant p53s generate pro-invasive niches by influencing exosome podocalyxin levels D Novo, N Heath, L Mitchell, G Caligiuri, A MacFarlane, D Reijmer, ... Nature communications 9 (1), 5069, 2018 | 114 | 2018 |
Increased formate overflow is a hallmark of oxidative cancer J Meiser, A Schuster, M Pietzke, J Vande Voorde, D Athineos, K Oizel, ... Nature communications 9 (1), 1368, 2018 | 102 | 2018 |
Targeting the metabolic response to statin-mediated oxidative stress produces a synergistic antitumor response GH McGregor, AD Campbell, SK Fey, S Tumanov, D Sumpton, GR Blanco, ... Cancer research 80 (2), 175-188, 2020 | 97 | 2020 |
Glutaminolysis drives membrane trafficking to promote invasiveness of breast cancer cells E Dornier, N Rabas, L Mitchell, D Novo, S Dhayade, S Marco, G Mackay, ... Nature communications 8 (1), 2255, 2017 | 85 | 2017 |
Polarized cell motility induces hydrogen peroxide to inhibit cofilin via cysteine oxidation JM Cameron, M Gabrielsen, YH Chim, J Munro, EJ McGhee, D Sumpton, ... Current Biology 25 (11), 1520-1525, 2015 | 79 | 2015 |
Nodulation Gene Mutants of Mesorhizobium loti R7A—nodZ and nolL Mutants Have Host-Specific Phenotypes on Lotus spp. P Rodpothong, JT Sullivan, K Songsrirote, D Sumpton, KWJT Cheung, ... Molecular plant-microbe interactions 22 (12), 1546-1554, 2009 | 76 | 2009 |
Rho kinase inhibition by AT13148 blocks pancreatic ductal adenocarcinoma invasion and tumor growth N Rath, J Munro, MF Cutiongco, A Jagiełło, N Gadegaard, L McGarry, ... Cancer research 78 (12), 3321-3336, 2018 | 73 | 2018 |
The initiator methionine tRNA drives secretion of type II collagen from stromal fibroblasts to promote tumor growth and angiogenesis CJ Clarke, TJ Berg, J Birch, D Ennis, L Mitchell, C Cloix, A Campbell, ... Current Biology 26 (6), 755-765, 2016 | 73 | 2016 |
Venetoclax causes metabolic reprogramming independent of BCL-2 inhibition A Roca-Portoles, G Rodriguez-Blanco, D Sumpton, C Cloix, M Mullin, ... Cell death & disease 11 (8), 616, 2020 | 71 | 2020 |
Colorectal tumors require NUAK1 for protection from oxidative stress J Port, N Muthalagu, M Raja, F Ceteci, T Monteverde, B Kruspig, A Hedley, ... Cancer Discovery, 2018 | 70 | 2018 |
NopM and NopD are rhizobial nodulation outer proteins: identification using LC-MALDI and LC-ESI with a monolithic capillary column JA Rodrigues, FJ Lopez-Baena, FJ Ollero, JM Vinardell, MR Espuny, ... Journal of proteome research 6 (3), 1029-1037, 2007 | 68 | 2007 |
Structural insights into ADP-ribosylation of ubiquitin by Deltex family E3 ubiquitin ligases C Chatrin, M Gabrielsen, L Buetow, MA Nakasone, SF Ahmed, ... Science Advances 6 (38), eabc0418, 2020 | 61 | 2020 |