The intestinal stem cell signature identifies colorectal cancer stem cells and predicts disease relapse A Merlos-Suárez, FM Barriga, P Jung, M Iglesias, MV Céspedes, ... Cell stem cell 8 (5), 511-524, 2011 | 1079 | 2011 |
Isolation and in vitro expansion of human colonic stem cells P Jung, T Sato, A Merlos-Suárez, FM Barriga, M Iglesias, D Rossell, ... Nature medicine 17 (10), 1225-1227, 2011 | 790 | 2011 |
Colon cancer cells colonize the lung from established liver metastases through p38 MAPK signalling and PTHLH J Urosevic, X Garcia-Albeniz, E Planet, S Real, MV Céspedes, M Guiu, ... Nature cell biology 16 (7), 685-694, 2014 | 195 | 2014 |
Mex3a marks a slowly dividing subpopulation of Lgr5+ intestinal stem cells FM Barriga, E Montagni, M Mana, M Mendez-Lago, ... Cell stem cell 20 (6), 801-816. e7, 2017 | 190 | 2017 |
A gene–environment-induced epigenetic program initiates tumorigenesis D Alonso-Curbelo, YJ Ho, C Burdziak, JLV Maag, JP Morris IV, ... Nature 590 (7847), 642-648, 2021 | 182 | 2021 |
Self-organized intestinal epithelial monolayers in crypt and villus-like domains show effective barrier function G Altay, E Larrañaga, S Tosi, FM Barriga, E Batlle, V Fernández-Majada, ... Scientific reports 9 (1), 10140, 2019 | 124 | 2019 |
Collective cell migration and metastases induced by an epithelial-to-mesenchymal transition in Drosophila intestinal tumors K Campbell, F Rossi, J Adams, I Pitsidianaki, FM Barriga, ... Nature communications 10 (1), 2311, 2019 | 103 | 2019 |
Isolation of human colon stem cells using surface expression of PTK7 P Jung, C Sommer, FM Barriga, SJ Buczacki, X Hernando-Momblona, ... Stem Cell Reports 5 (6), 979-987, 2015 | 69 | 2015 |
Epigenetic plasticity cooperates with cell-cell interactions to direct pancreatic tumorigenesis C Burdziak, D Alonso-Curbelo, T Walle, J Reyes, FM Barriga, D Haviv, ... Science 380 (6645), eadd5327, 2023 | 63 | 2023 |
Mex3a marks drug-tolerant persister colorectal cancer cells that mediate relapse after chemotherapy A Alvarez-Varela, L Novellasdemunt, FM Barriga, X Hernando-Momblona, ... Nature Cancer 3 (9), 1052-1070, 2022 | 63 | 2022 |
Conserved Mechanisms of Tumorigenesis in the Drosophila Adult Midgut Ò Martorell, A Merlos-Suarez, K Campbell, FM Barriga, CP Christov, ... PloS one 9 (2), e88413, 2014 | 61 | 2014 |
Base editing sensor libraries for high-throughput engineering and functional analysis of cancer-associated single nucleotide variants FJ Sánchez-Rivera, BJ Diaz, ER Kastenhuber, H Schmidt, A Katti, ... Nature biotechnology 40 (6), 862-873, 2022 | 59 | 2022 |
MACHETE identifies interferon-encompassing chromosome 9p21. 3 deletions as mediators of immune evasion and metastasis FM Barriga, KM Tsanov, YJ Ho, N Sohail, A Zhang, T Baslan, AN Wuest, ... Nature Cancer 3 (11), 1367-1385, 2022 | 57 | 2022 |
Senescence induction dictates response to chemo-and immunotherapy in preclinical models of ovarian cancer SV Paffenholz, C Salvagno, YJ Ho, M Limjoco, T Baslan, S Tian, A Kulick, ... Proceedings of the National Academy of Sciences 119 (5), e2117754119, 2022 | 53 | 2022 |
Somatic tissue engineering in mouse models reveals an actionable role for WNT pathway alterations in prostate cancer metastasis J Leibold, M Ruscetti, Z Cao, YJ Ho, T Baslan, M Zou, W Abida, J Feucht, ... Cancer discovery 10 (7), 1038-1057, 2020 | 46 | 2020 |
Bone marrow stromal cells modulate mouse ENT1 activity and protect leukemia cells from cytarabine induced apoptosis P Macanas-Pirard, A Leisewitz, R Broekhuizen, K Cautivo, FM Barriga, ... PLoS One 7 (5), e37203, 2012 | 42 | 2012 |
Iro/IRX transcription factors negatively regulate D pp/TGF‐β pathway activity during intestinal tumorigenesis Ò Martorell, FM Barriga, A Merlos‐Suárez, C Stephan‐Otto Attolini, ... EMBO reports 15 (11), 1210-1218, 2014 | 33 | 2014 |
KRAS mutants upregulate integrin β4 to promote invasion and metastasis in colorectal cancer SH Choi, JK Kim, CT Chen, C Wu, MR Marco, FM Barriga, K O'Rourke, ... Molecular Cancer Research 20 (8), 1305-1319, 2022 | 9 | 2022 |
KRAS mutant rectal cancer cells interact with surrounding fibroblasts to deplete the extracellular matrix JK Kim, MR Marco, SH Choi, X Qu, CT Chen, M Elkabets, L Fairchild, ... Molecular Oncology 15 (10), 2766-2781, 2021 | 6 | 2021 |
The viral nucleocapsid protein and the human RNA-binding protein Mex3A promote translation of the Andes orthohantavirus small mRNA J Vera-Otarola, E Castillo-Vargas, J Angulo, FM Barriga, E Batlle, ... PLoS Pathogens 17 (9), e1009931, 2021 | 5 | 2021 |