| An oncogenic super-enhancer formed through somatic mutation of a noncoding intergenic element MR Mansour, BJ Abraham, L Anders, A Berezovskaya, A Gutierrez, ... Science 346 (6215), 1373-1377, 2014 | 857 | 2014 |
| SCFFBW7 regulates cellular apoptosis by targeting MCL1 for ubiquitylation and destruction H Inuzuka, S Shaik, I Onoyama, D Gao, A Tseng, RS Maser, B Zhai, ... Nature 471 (7336), 104-109, 2011 | 692 | 2011 |
| High frequency of PTEN, PI3K, and AKT abnormalities in T-cell acute lymphoblastic leukemia A Gutierrez, T Sanda, R Grebliunaite, A Carracedo, L Salmena, Y Ahn, ... Blood, The Journal of the American Society of Hematology 114 (3), 647-650, 2009 | 505 | 2009 |
| Chromosomally unstable mouse tumours have genomic alterations similar to diverse human cancers RS Maser, B Choudhury, PJ Campbell, B Feng, KK Wong, A Protopopov, ... Nature 447 (7147), 966-971, 2007 | 451 | 2007 |
| An epigenetic mechanism of resistance to targeted therapy in T cell acute lymphoblastic leukemia B Knoechel, JE Roderick, KE Williamson, J Zhu, JG Lohr, MJ Cotton, ... Nature genetics 46 (4), 364-370, 2014 | 385 | 2014 |
| Core transcriptional regulatory circuit controlled by the TAL1 complex in human T cell acute lymphoblastic leukemia T Sanda, LN Lawton, MI Barrasa, ZP Fan, H Kohlhammer, A Gutierrez, ... Cancer cell 22 (2), 209-221, 2012 | 350 | 2012 |
| An “off-the-shelf” fratricide-resistant CAR-T for the treatment of T cell hematologic malignancies ML Cooper, J Choi, K Staser, JK Ritchey, JM Devenport, K Eckardt, ... Leukemia 32 (9), 1970-1983, 2018 | 338 | 2018 |
| The public repository of xenografts enables discovery and randomized phase II-like trials in mice EC Townsend, MA Murakami, A Christodoulou, AL Christie, J Köster, ... Cancer cell 29 (4), 574-586, 2016 | 332 | 2016 |
| Maturation stage of T-cell acute lymphoblastic leukemia determines BCL-2 versus BCL-XL dependence and sensitivity to ABT-199 TN Chonghaile, JE Roderick, C Glenfield, J Ryan, SE Sallan, ... Cancer discovery 4 (9), 1074-1087, 2014 | 275* | 2014 |
| Liquid chromatography/electron capture atmospheric pressure chemical ionization/mass spectrometry: analysis of pentafluorobenzyl derivatives of biomolecules and drugs in the … G Singh, A Gutierrez, K Xu, IA Blair Analytical chemistry 72 (14), 3007-3013, 2000 | 242 | 2000 |
| Phenothiazines induce PP2A-mediated apoptosis in T cell acute lymphoblastic leukemia A Gutierrez, L Pan, RWJ Groen, F Baleydier, A Kentsis, J Marineau, ... The Journal of clinical investigation 124 (2), 644-655, 2014 | 237 | 2014 |
| The BCL11B tumor suppressor is mutated across the major molecular subtypes of T-cell acute lymphoblastic leukemia A Gutierrez, A Kentsis, T Sanda, L Holmfeldt, SC Chen, J Zhang, ... Blood, The Journal of the American Society of Hematology 118 (15), 4169-4173, 2011 | 195 | 2011 |
| METTL1-mediated m7G modification of Arg-TCT tRNA drives oncogenic transformation EA Orellana, Q Liu, E Yankova, M Pirouz, E De Braekeleer, W Zhang, ... Molecular cell 81 (16), 3323-3338. e14, 2021 | 191 | 2021 |
| T-lymphoblastic lymphoma cells express high levels of BCL2, S1P1, and ICAM1, leading to a blockade of tumor cell intravasation H Feng, DL Stachura, RM White, A Gutierrez, L Zhang, T Sanda, CA Jette, ... Cancer cell 18 (4), 353-366, 2010 | 177 | 2010 |
| c-Myc inhibition prevents leukemia initiation in mice and impairs the growth of relapsed and induction failure pediatric T-ALL cells JE Roderick, J Tesell, LD Shultz, MA Brehm, DL Greiner, MH Harris, ... Blood, The Journal of the American Society of Hematology 123 (7), 1040-1050, 2014 | 176 | 2014 |
| Inactivation of ribosomal protein L22 promotes transformation by induction of the stemness factor, Lin28B S Rao, SY Lee, A Gutierrez, J Perrigoue, RJ Thapa, Z Tu, JR Jeffers, ... Blood, The Journal of the American Society of Hematology 120 (18), 3764-3773, 2012 | 168 | 2012 |
| Cyclin C is a haploinsufficient tumour suppressor N Li, A Fassl, J Chick, H Inuzuka, X Li, MR Mansour, L Liu, H Wang, ... Nature cell biology 16 (11), 1080-1091, 2014 | 163 | 2014 |
| The TAL1 complex targets the FBXW7 tumor suppressor by activating miR-223 in human T cell acute lymphoblastic leukemia MR Mansour, T Sanda, LN Lawton, X Li, T Kreslavsky, CD Novina, ... Journal of Experimental Medicine 210 (8), 1545-1557, 2013 | 148 | 2013 |
| Heat‐shock induction of T‐cell lymphoma/leukaemia in conditional Cre/lox‐regulated transgenic zebrafish H Feng, DM Langenau, JA Madge, A Quinkertz, A Gutierrez, DS Neuberg, ... British journal of haematology 138 (2), 169-175, 2007 | 147 | 2007 |
| TYK2–STAT1–BCL2 pathway dependence in T-cell acute lymphoblastic leukemia T Sanda, JW Tyner, A Gutierrez, VN Ngo, J Glover, BH Chang, A Yost, ... Cancer discovery 3 (5), 564-577, 2013 | 142 | 2013 |
