Locus coeruleus volume and cell population changes during Alzheimer's disease progression: a stereological study in human postmortem brains with potential implication for early … P Theofilas, AJ Ehrenberg, S Dunlop, ATDL Alho, A Nguy, REP Leite, ... Alzheimer's & Dementia 13 (3), 236-246, 2017 | 333 | 2017 |
A ketogenic diet suppresses seizures in mice through adenosine A1 receptors SA Masino, T Li, P Theofilas, US Sandau, DN Ruskin, BB Fredholm, ... The Journal of clinical investigation 121 (7), 2679-2683, 2011 | 318 | 2011 |
Quantifying the accretion of hyperphosphorylated tau in the locus coeruleus and dorsal raphe nucleus: the pathological building blocks of early Alzheimer's disease AJ Ehrenberg, AK Nguy, P Theofilas, S Dunlop, CK Suemoto, ... Neuropathology and applied neurobiology 43 (5), 393-408, 2017 | 189 | 2017 |
The role of the hippocampus in object recognition in rats: examination of the influence of task parameters and lesion size JA Ainge, C Heron-Maxwell, P Theofilas, P Wright, L de Hoz, ER Wood Behavioural brain research 167 (1), 183-195, 2006 | 172 | 2006 |
Probing the correlation of neuronal loss, neurofibrillary tangles, and cell death markers across the Alzheimer's disease Braak stages: a quantitative study in humans P Theofilas, AJ Ehrenberg, A Nguy, JM Thackrey, S Dunlop, MB Mejia, ... Neurobiology of aging 61, 1-12, 2018 | 122 | 2018 |
Argyrophilic grain disease differs from other tauopathies by lacking tau acetylation LT Grinberg, X Wang, C Wang, PD Sohn, P Theofilas, M Sidhu, ... Acta neuropathologica 125, 581-593, 2013 | 109 | 2013 |
The mechanistic link between selective vulnerability of the locus coeruleus and neurodegeneration in Alzheimer’s disease BJ Matchett, LT Grinberg, P Theofilas, ME Murray Acta neuropathologica 141 (5), 631-650, 2021 | 105 | 2021 |
Adenosine kinase as a target for therapeutic antisense strategies in epilepsy P Theofilas, S Brar, KA Stewart, HY Shen, US Sandau, D Poulsen, ... Epilepsia 52 (3), 589-601, 2011 | 105 | 2011 |
Turning on the light within: subcortical nuclei of the isodentritic core and their role in Alzheimer’s disease pathogenesis P Theofilas, S Dunlop, H Heinsen, LT Grinberg Journal of Alzheimer's Disease 46 (1), 17-34, 2015 | 104 | 2015 |
Profound degeneration of wake-promoting neurons in Alzheimer's disease J Oh, RA Eser, AJ Ehrenberg, D Morales, C Petersen, J Kudlacek, ... Alzheimer's & Dementia 15 (10), 1253-1263, 2019 | 97 | 2019 |
A comprehensive resource for induced pluripotent stem cells from patients with primary tauopathies CM Karch, AW Kao, A Karydas, K Onanuga, R Martinez, A Argouarch, ... Stem cell reports 13 (5), 939-955, 2019 | 78 | 2019 |
Homeostatic control of synaptic activity by endogenous adenosine is mediated by adenosine kinase MJ Diógenes, R Neves-Tomé, S Fucile, K Martinello, M Scianni, ... Cerebral cortex 24 (1), 67-80, 2014 | 68 | 2014 |
Specificity for latent C termini links the E3 ubiquitin ligase CHIP to caspases M Ravalin, P Theofilas, K Basu, KA Opoku-Nsiah, VA Assimon, ... Nature chemical biology 15 (8), 786-794, 2019 | 66 | 2019 |
Selective vulnerability of brainstem nuclei in distinct tauopathies: a postmortem study RA Eser, AJ Ehrenberg, C Petersen, S Dunlop, MB Mejia, CK Suemoto, ... Journal of Neuropathology & Experimental Neurology 77 (2), 149-161, 2018 | 47 | 2018 |
The proapoptotic BCL-2 homology domain 3-only protein Bim is not critical for acute excitotoxic cell death P Theofilas, P Bedner, K Hüttmann, M Theis, C Steinhäuser, S Frank Journal of Neuropathology & Experimental Neurology 68 (1), 102-110, 2009 | 29 | 2009 |
Automating cell detection and classification in human brain fluorescent microscopy images using dictionary learning and sparse coding M Alegro, P Theofilas, A Nguy, PA Castruita, W Seeley, H Heinsen, ... Journal of neuroscience methods 282, 20-33, 2017 | 27 | 2017 |
Astrocytes derived from fetal neural progenitor cells as a novel source for therapeutic adenosine delivery A Van Dycke, R Raedt, A Verstraete, P Theofilas, W Wadman, K Vonck, ... Seizure 19 (7), 390-396, 2010 | 24 | 2010 |
Morphological study of a connexin 43‐GFP reporter mouse highlights glial heterogeneity, amacrine cells, and olfactory ensheathing cells P Theofilas, C Steinhäuser, M Theis, A Derouiche Journal of neuroscience research 95 (11), 2182-2194, 2017 | 23 | 2017 |
A novel approach for integrative studies on neurodegenerative diseases in human brains P Theofilas, L Polichiso, X Wang, LC Lima, ATL Alho, REP Leite, ... Journal of neuroscience methods 226, 171-183, 2014 | 22 | 2014 |
Caspase‐6‐cleaved tau is relevant in Alzheimer's disease and marginal in four‐repeat tauopathies: Diagnostic and therapeutic implications P Theofilas, AMH Piergies, I Oh, YB Lee, SH Li, FL Pereira, C Petersen, ... Neuropathology and applied neurobiology 48 (5), e12819, 2022 | 8 | 2022 |