Phosphine-catalyzed asymmetric organic reactions H Ni, WL Chan, Y Lu Chemical reviews 118 (18), 9344-9411, 2018 | 589 | 2018 |
Optimization of lipid nanoparticles for the delivery of nebulized therapeutic mRNA to the lungs MP Lokugamage, D Vanover, J Beyersdorf, MZC Hatit, L Rotolo, ... Nature biomedical engineering 5 (9), 1059-1068, 2021 | 272 | 2021 |
Enantioselective Phosphine‐Catalyzed Formal [4+ 4] Annulation of α, β‐Unsaturated Imines and Allene Ketones: Construction of Eight‐Membered Rings H Ni, X Tang, W Zheng, W Yao, N Ullah, Y Lu Angewandte Chemie International Edition 56 (45), 14222-14226, 2017 | 181 | 2017 |
Piperazine-derived lipid nanoparticles deliver mRNA to immune cells in vivo H Ni, MZC Hatit, K Zhao, D Loughrey, MP Lokugamage, HE Peck, AD Cid, ... Nature Communications 13 (1), 4766, 2022 | 89 | 2022 |
Species-dependent in vivo mRNA delivery and cellular responses to nanoparticles MZC Hatit, MP Lokugamage, CN Dobrowolski, K Paunovska, H Ni, ... Nature nanotechnology 17 (3), 310-318, 2022 | 83 | 2022 |
Catalyst-controlled regioselectivity in phosphine catalysis: the synthesis of spirocyclic benzofuranones via regiodivergent [3+ 2] annulations of aurones and an allenoate H Ni, Z Yu, W Yao, Y Lan, N Ullah, Y Lu Chemical Science 8 (8), 5699-5704, 2017 | 78 | 2017 |
Enantioselective [4+ 2]-annulation of oxadienes and allenones catalyzed by an amino acid derived phosphine: Synthesis of functionalized dihydropyrans H Ni, W Yao, A Waheed, N Ullah, Y Lu Organic letters 18 (9), 2138-2141, 2016 | 59 | 2016 |
Nanoparticle single-cell multiomic readouts reveal that cell heterogeneity influences lipid nanoparticle-mediated messenger RNA delivery C Dobrowolski, K Paunovska, E Schrader Echeverri, D Loughrey, ... Nature Nanotechnology 17 (8), 871-879, 2022 | 58 | 2022 |
Chiral phosphine-mediated intramolecular [3+ 2] annulation: enhanced enantioselectivity by achiral Brønsted acid W Yao, Z Yu, S Wen, H Ni, N Ullah, Y Lan, Y Lu Chemical Science 8 (7), 5196-5200, 2017 | 44 | 2017 |
Highly enantioselective synthesis of dihydrocoumarin-fused dihydropyrans via the phosphine-catalyzed [4+ 2] annulation of allenones with 3-aroylcoumarins X Han, H Ni, WL Chan, X Gai, Y Wang, Y Lu Organic & Biomolecular Chemistry 14 (22), 5059-5064, 2016 | 43 | 2016 |
Nanoparticle stereochemistry-dependent endocytic processing improves in vivo mRNA delivery MZC Hatit, CN Dobrowolski, MP Lokugamage, D Loughrey, H Ni, C Zurla, ... Nature Chemistry 15 (4), 508-515, 2023 | 34 | 2023 |
The Transcriptional Response to Lung-Targeting Lipid Nanoparticles in Vivo A Radmand, MP Lokugamage, H Kim, C Dobrowolski, R Zenhausern, ... Nano letters 23 (3), 993-1002, 2023 | 34 | 2023 |
Highly Enantioselective [3+ 2] Annulation of 3-Butynoates with β-Trifluoromethyl Enones Promoted by an Amine− Phosphine Binary Catalytic System H Ni, YL Wong, M Wu, Z Han, K Ding, Y Lu Organic letters 22 (6), 2460-2463, 2020 | 27 | 2020 |
Phosphine-Catalyzed Formal Oxa-[4+ 2] Annulation Employing Nitroethylene and Enones: Enantioselective Synthesis of Dihydropyrans Z Jin, H Ni, B Zhou, W Zheng, Y Lu Organic letters 20 (17), 5515-5518, 2018 | 26 | 2018 |
Organocatalyzed [3+ 3] Annulations for the Construction of Heterocycles Y Zhu, Y Huang Synthesis 52 (08), 1181-1202, 2020 | 24 | 2020 |
Enantioselective [3+ 2] annulation of α-substituted allenoates with β, γ-unsaturated N-sulfonylimines catalyzed by a bifunctional dipeptide phosphine H Ni, W Yao, Y Lu Beilstein Journal of Organic Chemistry 12 (1), 343-348, 2016 | 20 | 2016 |
Phosphine-catalyzed enantioselective [4+ 1] annulation of oxindoles with allenic ketones for the construction of spirocyclopentene oxindoles X Tang, H Ni, Y Lu Organic Chemistry Frontiers 8 (16), 4485-4489, 2021 | 19 | 2021 |
Phosphine-catalyzed divergent domino processes between γ-substituted allenoates and carbonyl-activated alkenes M Wu, Z Han, H Ni, N Wang, K Ding, Y Lu Chemical Science 13 (11), 3161-3168, 2022 | 18 | 2022 |
Cationic cholesterol-dependent LNP delivery to lung stem cells, the liver, and heart A Radmand, H Kim, J Beyersdorf, CN Dobrowolski, R Zenhausern, ... Proceedings of the National Academy of Sciences 121 (11), e2307801120, 2024 | 11 | 2024 |
The promising therapeutic potential of oligonucleotides for pulmonary fibrotic diseases D Paul, MH Miller, J Born, S Samaddar, H Ni, H Avila, VR Krishnamurthy, ... Expert Opinion on Drug Discovery 18 (2), 193-206, 2023 | 6 | 2023 |