关注
Huanzhen Ni
Huanzhen Ni
Eli Lilly and Company
在 u.nus.edu 的电子邮件经过验证
标题
引用次数
引用次数
年份
Phosphine-catalyzed asymmetric organic reactions
H Ni, WL Chan, Y Lu
Chemical reviews 118 (18), 9344-9411, 2018
5892018
Optimization of lipid nanoparticles for the delivery of nebulized therapeutic mRNA to the lungs
MP Lokugamage, D Vanover, J Beyersdorf, MZC Hatit, L Rotolo, ...
Nature biomedical engineering 5 (9), 1059-1068, 2021
2722021
Enantioselective Phosphine‐Catalyzed Formal [4+ 4] Annulation of α, β‐Unsaturated Imines and Allene Ketones: Construction of Eight‐Membered Rings
H Ni, X Tang, W Zheng, W Yao, N Ullah, Y Lu
Angewandte Chemie International Edition 56 (45), 14222-14226, 2017
1812017
Piperazine-derived lipid nanoparticles deliver mRNA to immune cells in vivo
H Ni, MZC Hatit, K Zhao, D Loughrey, MP Lokugamage, HE Peck, AD Cid, ...
Nature Communications 13 (1), 4766, 2022
892022
Species-dependent in vivo mRNA delivery and cellular responses to nanoparticles
MZC Hatit, MP Lokugamage, CN Dobrowolski, K Paunovska, H Ni, ...
Nature nanotechnology 17 (3), 310-318, 2022
832022
Catalyst-controlled regioselectivity in phosphine catalysis: the synthesis of spirocyclic benzofuranones via regiodivergent [3+ 2] annulations of aurones and an allenoate
H Ni, Z Yu, W Yao, Y Lan, N Ullah, Y Lu
Chemical Science 8 (8), 5699-5704, 2017
782017
Enantioselective [4+ 2]-annulation of oxadienes and allenones catalyzed by an amino acid derived phosphine: Synthesis of functionalized dihydropyrans
H Ni, W Yao, A Waheed, N Ullah, Y Lu
Organic letters 18 (9), 2138-2141, 2016
592016
Nanoparticle single-cell multiomic readouts reveal that cell heterogeneity influences lipid nanoparticle-mediated messenger RNA delivery
C Dobrowolski, K Paunovska, E Schrader Echeverri, D Loughrey, ...
Nature Nanotechnology 17 (8), 871-879, 2022
582022
Chiral phosphine-mediated intramolecular [3+ 2] annulation: enhanced enantioselectivity by achiral Brønsted acid
W Yao, Z Yu, S Wen, H Ni, N Ullah, Y Lan, Y Lu
Chemical Science 8 (7), 5196-5200, 2017
442017
Highly enantioselective synthesis of dihydrocoumarin-fused dihydropyrans via the phosphine-catalyzed [4+ 2] annulation of allenones with 3-aroylcoumarins
X Han, H Ni, WL Chan, X Gai, Y Wang, Y Lu
Organic & Biomolecular Chemistry 14 (22), 5059-5064, 2016
432016
Nanoparticle stereochemistry-dependent endocytic processing improves in vivo mRNA delivery
MZC Hatit, CN Dobrowolski, MP Lokugamage, D Loughrey, H Ni, C Zurla, ...
Nature Chemistry 15 (4), 508-515, 2023
342023
The Transcriptional Response to Lung-Targeting Lipid Nanoparticles in Vivo
A Radmand, MP Lokugamage, H Kim, C Dobrowolski, R Zenhausern, ...
Nano letters 23 (3), 993-1002, 2023
342023
Highly Enantioselective [3+ 2] Annulation of 3-Butynoates with β-Trifluoromethyl Enones Promoted by an Amine− Phosphine Binary Catalytic System
H Ni, YL Wong, M Wu, Z Han, K Ding, Y Lu
Organic letters 22 (6), 2460-2463, 2020
272020
Phosphine-Catalyzed Formal Oxa-[4+ 2] Annulation Employing Nitroethylene and Enones: Enantioselective Synthesis of Dihydropyrans
Z Jin, H Ni, B Zhou, W Zheng, Y Lu
Organic letters 20 (17), 5515-5518, 2018
262018
Organocatalyzed [3+ 3] Annulations for the Construction of Heterocycles
Y Zhu, Y Huang
Synthesis 52 (08), 1181-1202, 2020
242020
Enantioselective [3+ 2] annulation of α-substituted allenoates with β, γ-unsaturated N-sulfonylimines catalyzed by a bifunctional dipeptide phosphine
H Ni, W Yao, Y Lu
Beilstein Journal of Organic Chemistry 12 (1), 343-348, 2016
202016
Phosphine-catalyzed enantioselective [4+ 1] annulation of oxindoles with allenic ketones for the construction of spirocyclopentene oxindoles
X Tang, H Ni, Y Lu
Organic Chemistry Frontiers 8 (16), 4485-4489, 2021
192021
Phosphine-catalyzed divergent domino processes between γ-substituted allenoates and carbonyl-activated alkenes
M Wu, Z Han, H Ni, N Wang, K Ding, Y Lu
Chemical Science 13 (11), 3161-3168, 2022
182022
Cationic cholesterol-dependent LNP delivery to lung stem cells, the liver, and heart
A Radmand, H Kim, J Beyersdorf, CN Dobrowolski, R Zenhausern, ...
Proceedings of the National Academy of Sciences 121 (11), e2307801120, 2024
112024
The promising therapeutic potential of oligonucleotides for pulmonary fibrotic diseases
D Paul, MH Miller, J Born, S Samaddar, H Ni, H Avila, VR Krishnamurthy, ...
Expert Opinion on Drug Discovery 18 (2), 193-206, 2023
62023
系统目前无法执行此操作,请稍后再试。
文章 1–20