A small molecule targeting mutagenic translesion synthesis improves chemotherapy JL Wojtaszek, N Chatterjee, J Najeeb, A Ramos, M Lee, K Bian, JY Xue, ... Cell 178 (1), 152-159. e11, 2019 | 153 | 2019 |
Oncometabolites d- and l-2-Hydroxyglutarate Inhibit the AlkB Family DNA Repair Enzymes under Physiological Conditions F Chen, K Bian, Q Tang, BI Fedeles, V Singh, ZT Humulock, ... Chemical research in toxicology 30 (4), 1102-1110, 2017 | 82 | 2017 |
DNA repair enzymes ALKBH2, ALKBH3, and AlkB oxidize 5-methylcytosine to 5-hydroxymethylcytosine, 5-formylcytosine and 5-carboxylcytosine in vitro K Bian, SAP Lenz, Q Tang, F Chen, R Qi, M Jost, CL Drennan, ... Nucleic acids research 47 (11), 5522-5529, 2019 | 56 | 2019 |
Adaptive response enzyme AlkB preferentially repairs 1-methylguanine and 3-methylthymine adducts in double-stranded DNA F Chen, Q Tang, K Bian, ZT Humulock, X Yang, M Jost, CL Drennan, ... Chemical research in toxicology 29 (4), 687-693, 2016 | 50 | 2016 |
Rev7 loss alters cisplatin response and increases drug efficacy in chemotherapy-resistant lung cancer FM Vassel, K Bian, GC Walker, MT Hemann Proceedings of the National Academy of Sciences 117 (46), 28922-28924, 2020 | 28 | 2020 |
A haem-sequestering plant peptide promotes iron uptake in symbiotic bacteria S Sankari, VMP Babu, K Bian, A Alhhazmi, MC Andorfer, DM Avalos, ... Nature microbiology 7 (9), 1453-1465, 2022 | 27 | 2022 |
Copper inhibits the AlkB family DNA repair enzymes under Wilson’s disease condition K Bian, F Chen, ZT Humulock, Q Tang, D Li Chemical research in toxicology 30 (10), 1794-1796, 2017 | 22 | 2017 |
Hydrolyzable tannins are iron chelators that inhibit DNA repair enzyme ALKBH2 F Chen, Q Tang, H Ma, K Bian, NP Seeram, D Li Chemical research in toxicology 32 (6), 1082-1086, 2019 | 21 | 2019 |
Characterization of byproducts from chemical syntheses of oligonucleotides containing 1-methyladenine and 3-methylcytosine Q Tang, A Cai, K Bian, F Chen, JC Delaney, S Adusumalli, AC Bach, ... ACS omega 2 (11), 8205-8212, 2017 | 16 | 2017 |
Comparison of the Base Excision and Direct Reversal Repair Pathways for Correcting 1,N6-Ethenoadenine in Strongly Positioned Nucleosome Core Particles PJ Caffrey, R Kher, K Bian, D Li, S Delaney Chemical research in toxicology 33 (7), 1888-1896, 2020 | 11 | 2020 |
Probing the effect of bulky lesion-induced replication fork conformational heterogeneity using 4-Aminobiphenyl-modified DNA A Cai, K Bian, F Chen, Q Tang, R Carley, D Li, BP Cho Molecules 24 (8), 1566, 2019 | 4 | 2019 |
Sequence Dependent Repair of 1,N6-Ethenoadenine by DNA Repair Enzymes ALKBH2, ALKBH3, and AlkB R Qi, K Bian, F Chen, Q Tang, X Zhou, D Li Molecules 26 (17), 5285, 2021 | 3 | 2021 |
Biological Evaluation of DNA Biomarkers in a Chemically Defined and Site-Specific Manner K Bian, JC Delaney, X Zhou, D Li Toxics 7 (2), 36, 2019 | 3 | 2019 |
Stable Interstrand Cross-Links Generated from the Repair of 1,N6-Ethenoadenine in DNA by α-Ketoglutarate/Fe(II)-Dependent Dioxygenase ALKBH2 J Wang, NA Takyi, YC Hsiao, Q Tang, YT Chen, CW Liu, J Ma, R Qi, ... Journal of the American Chemical Society 146 (15), 10381-10392, 2024 | 1 | 2024 |
REV7 Monomer Is Unable to Participate in Double Strand Break Repair and Translesion Synthesis but Suppresses Mitotic Errors FM Vassel, DJ Laverty, K Bian, CG Piett, MT Hemann, GC Walker, ... International Journal of Molecular Sciences 24 (21), 15799, 2023 | | 2023 |
Effect of sequence context on 1, N6-ethenoadenine repair by the AlkB family DNA repair enzymes R Qi, K Bian, Q Tang, F Chen, D Li ABSTRACTS OF PAPERS OF THE AMERICAN CHEMICAL SOCIETY 258, 2019 | | 2019 |
DNA Damage, Repair, and Mutational Spectrum K Bian University of Rhode Island, 2019 | | 2019 |
ADAPTIVE RESPONSE ENZYME ALKB PREFERENTIALLY REPAIRS 1‑METHYLGUANINE AND 3‑METHYLTHYMINE ADDUCTS IN DOUBLE-STRANDED DNA [PUBLISHED ON CHEMICAL RESEARCH IN TOXICOLOGY 2016, 29 … F Chen, Q Tang, K Bian, ZT Humulock, X Yang, M Jost, CL Drennan, ... CHEMICAL SYNTHESIS, CHARACTERIZATION AND BIOLOGICAL EVALUATION OF …, 2019 | | 2019 |
HYDROLYSABLE TANNINS ARE IRON CHELATORS THAT INHIBIT DNA REPAIR ENZYME ALKBH2 [SUBMITTED TO CHEMICAL RESEARCH IN TOXICOLOGY] F Chen, Q Tang, H Ma, K Bian, NP Seeram, D Li, QT FC CHEMICAL SYNTHESIS, CHARACTERIZATION AND BIOLOGICAL EVALUATION OF …, 2019 | | 2019 |
GLYCATION BY GLUCOSE 6-PHOSPHATE INDUCES G TO T MUTATION AND SINGLE NUCLEOTIDE DELETION IN CELL [MANUSCRIPT IN PREPARATION] Q Tang, K Bian, F Chen, D Li CHEMICAL SYNTHESIS, CHARACTERIZATION AND BIOLOGICAL EVALUATION OF …, 2019 | | 2019 |