Genomic hallmarks and structural variation in metastatic prostate cancer DA Quigley, HX Dang, SG Zhao, P Lloyd, R Aggarwal, JJ Alumkal, A Foye, ... Cell 174 (3), 758-769. e9, 2018 | 655 | 2018 |
The mutational landscapes of genetic and chemical models of Kras-driven lung cancer PMK Westcott, KD Halliwill, MD To, M Rashid, AG Rust, TM Keane, ... Nature 517 (7535), 489-492, 2015 | 354 | 2015 |
TP53 Mutation Spectrum in Breast Cancer Is Subtype Specific and Has Distinct Prognostic Relevance L Silwal-Pandit, HKM Vollan, SF Chin, OM Rueda, S McKinney, T Osako, ... Clinical Cancer Research 20 (13), 3569-3580, 2014 | 313 | 2014 |
Analysis of Circulating Cell-Free DNA Identifies Multiclonal Heterogeneity of BRCA2 Reversion Mutations Associated with Resistance to PARP Inhibitors D Quigley, JJ Alumkal, AW Wyatt, V Kothari, A Foye, P Lloyd, R Aggarwal, ... Cancer discovery 7 (9), 999-1005, 2017 | 265 | 2017 |
The DNA methylation landscape of advanced prostate cancer SG Zhao, WS Chen, H Li, A Foye, M Zhang, M Sjöström, R Aggarwal, ... Nature genetics 52 (8), 778-789, 2020 | 242 | 2020 |
Transcription-associated cyclin-dependent kinases as targets and biomarkers for cancer therapy J Chou, DA Quigley, TM Robinson, FY Feng, A Ashworth Cancer discovery 10 (3), 351-370, 2020 | 200 | 2020 |
Genetic architecture of mouse skin inflammation and tumour susceptibility DA Quigley, MD To, J Pérez-Losada, FG Pelorosso, JH Mao, H Nagase, ... Nature 458 (7237), 505-508, 2009 | 155 | 2009 |
Genomic drivers of poor prognosis and enzalutamide resistance in metastatic castration-resistant prostate cancer WS Chen, R Aggarwal, L Zhang, SG Zhao, GV Thomas, TM Beer, ... European urology 76 (5), 562-571, 2019 | 132 | 2019 |
Predicting prognosis and therapeutic response from interactions between lymphocytes and tumor cells DA Quigley, V Kristensen Molecular oncology 9 (10), 2054-2062, 2015 | 125 | 2015 |
Large-scale profiling of kinase dependencies in cancer cell lines J Campbell, CJ Ryan, R Brough, I Bajrami, HN Pemberton, IY Chong, ... Cell reports 14 (10), 2490-2501, 2016 | 121 | 2016 |
Transcriptional profiling identifies an androgen receptor activity-low, stemness program associated with enzalutamide resistance JJ Alumkal, D Sun, E Lu, TM Beer, GV Thomas, E Latour, R Aggarwal, ... Proceedings of the National Academy of Sciences 117 (22), 12315-12323, 2020 | 106 | 2020 |
A single H/ACA small nucleolar RNA mediates tumor suppression downstream of oncogenic RAS M McMahon, A Contreras, M Holm, T Uechi, CM Forester, X Pang, ... Elife 8, e48847, 2019 | 104 | 2019 |
Deep whole-genome ctDNA chronology of treatment-resistant prostate cancer C Herberts, M Annala, J Sipola, SWS Ng, XE Chen, A Nurminen, ... Nature 608 (7921), 199-208, 2022 | 101 | 2022 |
Commonly occurring cell subsets in high-grade serous ovarian tumors identified by single-cell mass cytometry VD Gonzalez, N Samusik, TJ Chen, ES Savig, N Aghaeepour, DA Quigley, ... Cell reports 22 (7), 1875-1888, 2018 | 91 | 2018 |
Outgrowth of drug-resistant carcinomas expressing markers of tumor aggression after long-term TβRI/II kinase inhibition with LY2109761 EC Connolly, EF Saunier, D Quigley, MT Luu, A De Sapio, B Hann, ... Cancer research 71 (6), 2339-2349, 2011 | 87 | 2011 |
Deletion of the PER3 Gene on Chromosome 1p36 in Recurrent ER-Positive Breast Cancer J Climent, J Perez-Losada, DA Quigley, IJ Kim, R Delrosario, KY Jen, ... Journal of Clinical Oncology 28 (23), 3770-3778, 2010 | 84 | 2010 |
Mouse and human strategies identify PTPN14 as a modifier of angiogenesis and hereditary haemorrhagic telangiectasia M Benzinou, FF Clermont, TGW Letteboer, J Kim, S Espejel, KA Harradine, ... Nature communications 3 (1), 616, 2012 | 82 | 2012 |
Inflammation and Hras signaling control epithelial–mesenchymal transition during skin tumor progression CE Wong, SY Jennifer, DA Quigley, MD To, KY Jen, PY Huang, ... Genes & development 27 (6), 670-682, 2013 | 75 | 2013 |
Lymphocyte Invasion in IC10/Basal-Like Breast Tumors Is Associated with Wild-Type TP53 D Quigley, L Silwal-Pandit, R Dannenfelser, A Langerød, HKM Vollan, ... Molecular Cancer Research 13 (3), 493-501, 2015 | 74 | 2015 |
Systems genetics analysis of cancer susceptibility: from mouse models to humans D Quigley, A Balmain Nature Reviews Genetics 10 (9), 651-657, 2009 | 68 | 2009 |