| Identification of the Zn2+ binding site and mode of operation of a mammalian Zn2+ transporter E Ohana, E Hoch, C Keasar, T Kambe, O Yifrach, M Hershfinkel, I Sekler Journal of Biological Chemistry 284 (26), 17677-17686, 2009 | 226 | 2009 |
| Type 2 diabetes variants disrupt function of SLC16A11 through two distinct mechanisms V Rusu, E Hoch, JM Mercader, DE Tenen, M Gymrek, CR Hartigan, ... Cell 170 (1), 199-212. e20, 2017 | 169 | 2017 |
| Histidine pairing at the metal transport site of mammalian ZnT transporters controls Zn2+ over Cd2+ selectivity E Hoch, W Lin, J Chai, M Hershfinkel, D Fu, I Sekler Proceedings of the National Academy of Sciences 109 (19), 7202-7207, 2012 | 141 | 2012 |
| Elucidating the H+ Coupled Zn2+ Transport Mechanism of ZIP4; Implications in Acrodermatitis Enteropathica E Hoch, M Levy, M Hershfinkel, I Sekler International Journal of Molecular Sciences 21 (3), 734, 2020 | 36 | 2020 |
| Zinc transporter 10 (ZnT10)-dependent extrusion of cellular Mn2+ is driven by an active Ca2+-coupled exchange M Levy, N Elkoshi, S Barber-Zucker, E Hoch, R Zarivach, M Hershfinkel, ... Journal of Biological Chemistry 294 (15), 5879-5889, 2019 | 36 | 2019 |
| The PP-motif in luminal loop 2 of ZnT transporters plays a pivotal role in TNAP activation S Fujimoto, T Tsuji, T Fujiwara, T Takeda, C Merriman, A Fukunaka, ... Biochemical Journal 473 (17), 2611-2621, 2016 | 27 | 2016 |
| Gain-of-function claims for type-2-diabetes-associated coding variants in SLC16A11 are not supported by the experimental data E Hoch, JC Florez, ES Lander, SBR Jacobs Cell Reports 29 (3), 778-780, 2019 | 10 | 2019 |
| Type 2 Diabetes‐Associated Variants Disrupt Function of SLC16A11, a Proton‐Coupled Monocarboxylate Transporter, Through Two Distinct Mechanisms E Hoch, V Rusu, SL Schreiber, JC Florez, SBR Jacobs, ES Lander The FASEB Journal 31, 950.2-950.2, 2017 | 4 | 2017 |
| Mct11 deficiency alters hepatic glucose metabolism and energy homeostasis A Ainbinder, L Zhao, P Glover, K Gelinas-Roa, V Rusu, A Harney, E Hoch, ... bioRxiv, 2021.09. 08.459307, 2021 | 3 | 2021 |
| Compositions and methods for detecting and treating diabetes E Hoch, SBR Jacobs, V Rusu, L Zhao, JMM Bigas US Patent 11,471,462, 2022 | | 2022 |
| S5. 2-SLC16A11: From human genetics to novel mechanisms underlying type 2 diabetes E Hoch Drug Metabolism and Pharmacokinetics 35 (1), S10, 2020 | | 2020 |
| Mode of Operation and Basis for Metal Selectivity in Mammalian Zinc Transporters E Hoch Ben-Gurion University of the Negev, Faculty of Health Sciences, Department …, 2014 | | 2014 |
