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Scott Furlan
Scott Furlan
在 fredhutch.org 的电子邮件经过验证
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Comprehensive single-cell transcriptional profiling of a multicellular organism
J Cao, JS Packer, V Ramani, DA Cusanovich, C Huynh, R Daza, X Qiu, ...
Science 357 (6352), 661-667, 2017
13982017
Immunogenic chemotherapy enhances recruitment of CAR-T cells to lung tumors and improves antitumor efficacy when combined with checkpoint blockade
S Srivastava, SN Furlan, CA Jaeger-Ruckstuhl, M Sarvothama, C Berger, ...
Cancer cell 39 (2), 193-208. e10, 2021
2392021
Chimeric antigen receptor T cell–mediated neurotoxicity in nonhuman primates
A Taraseviciute, V Tkachev, R Ponce, CJ Turtle, JM Snyder, HD Liggitt, ...
Cancer discovery 8 (6), 750-763, 2018
2302018
A novel technique for the fluorometric assessment of T lymphocyte antigen specific lysis
ME Sheehy, AB McDermott, SN Furlan, P Klenerman, DF Nixon
Journal of immunological methods 249 (1-2), 99-110, 2001
2082001
Phase II trial of costimulation blockade with abatacept for prevention of acute GVHD
B Watkins, M Qayed, C McCracken, B Bratrude, K Betz, Y Suessmuth, ...
Journal of clinical oncology 39 (17), 1865-1877, 2021
1802021
Single-cell CUT&Tag analysis of chromatin modifications in differentiation and tumor progression
SJ Wu, SN Furlan, AB Mihalas, HS Kaya-Okur, AH Feroze, SN Emerson, ...
Nature biotechnology 39 (7), 819-824, 2021
1552021
Characterization of the immune microenvironment of diffuse intrinsic pontine glioma: implications for development of immunotherapy
NAP Lieberman, K DeGolier, HM Kovar, A Davis, V Hoglund, J Stevens, ...
Neuro-oncology 21 (1), 83-94, 2019
1532019
Programmed death ligand-1 expression on donor T cells drives graft-versus-host disease lethality
A Saha, RS O’Connor, G Thangavelu, SB Lovitch, DB Dandamudi, ...
The Journal of clinical investigation 126 (7), 2642-2660, 2016
992016
HIV-specific CD8+ T cell function in children with vertically acquired HIV-1 infection is critically influenced by age and the state of the CD4+ T cell compartment
JK Sandberg, NM Fast, KA Jordan, SN Furlan, JD Barbour, G Fennelly, ...
The Journal of Immunology 170 (8), 4403-4410, 2003
872003
Combined OX40L and mTOR blockade controls effector T cell activation while preserving Treg reconstitution after transplant
V Tkachev, SN Furlan, B Watkins, DJ Hunt, HB Zheng, ...
Science translational medicine 9 (408), eaan3085, 2017
782017
Transcriptome analysis of GVHD reveals aurora kinase A as a targetable pathway for disease prevention
SN Furlan, B Watkins, V Tkachev, R Flynn, S Cooley, S Ramakrishnan, ...
Science translational medicine 7 (315), 315ra191-315ra191, 2015
642015
Spatiotemporal single-cell profiling reveals that invasive and tissue-resident memory donor CD8+ T cells drive gastrointestinal acute graft-versus-host disease
V Tkachev, J Kaminski, EL Potter, SN Furlan, A Yu, DJ Hunt, C McGuckin, ...
Science translational medicine 13 (576), eabc0227, 2021
532021
Human CD19-targeted mouse T cells induce B cell aplasia and toxicity in human CD19 transgenic mice
CA Pennell, JL Barnum, CS McDonald-Hyman, A Panoskaltsis-Mortari, ...
Molecular Therapy 26 (6), 1423-1434, 2018
532018
CD28 blockade controls T cell activation to prevent graft-versus-host disease in primates
BK Watkins, V Tkachev, SN Furlan, DJ Hunt, K Betz, A Yu, M Brown, ...
The Journal of Clinical Investigation 128 (9), 3991-4007, 2018
512018
Systems analysis uncovers inflammatory Th/Tc17-driven modules during acute GVHD in monkey and human T cells
SN Furlan, B Watkins, V Tkachev, S Cooley, A Panoskaltsis-Mortari, ...
Blood, The Journal of the American Society of Hematology 128 (21), 2568-2579, 2016
482016
IL-2 enhances ex vivo–expanded regulatory T-cell persistence after adoptive transfer
SN Furlan, K Singh, C Lopez, V Tkachev, DJ Hunt, J Hibbard, KM Betz, ...
Blood Advances 4 (8), 1594-1605, 2020
342020
CD8-predominant T-cell CNS infiltration accompanies GVHD in primates and is improved with immunoprophylaxis
S Kaliyaperumal, B Watkins, P Sharma, S Furlan, S Ramakrishnan, ...
Blood, The Journal of the American Society of Hematology 123 (12), 1967-1969, 2014
322014
The knife’s edge of tolerance: inducing stable multilineage mixed chimerism but with a significant risk of CMV reactivation and disease in rhesus macaques
HB Zheng, B Watkins, V Tkachev, S Yu, D Tran, S Furlan, K Zeleski, ...
American Journal of Transplantation 17 (3), 657-670, 2017
292017
Integrated stem cell signature and cytomolecular risk determination in pediatric acute myeloid leukemia
BJ Huang, JL Smith, JE Farrar, YC Wang, M Umeda, RE Ries, AR Leonti, ...
Nature Communications 13 (1), 5487, 2022
272022
Changes in CD4+ T-cell differentiation phenotype during structured treatment interruption in patients with chronic HIV-1 infection
TH Alexander, GM Ortiz, MF Wellons, A Allen, EJ Grace, B Schweighardt, ...
JAIDS Journal of Acquired Immune Deficiency Syndromes 34 (5), 475-481, 2003
272003
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