Towards personalized computational oncology: from spatial models of tumour spheroids, to organoids, to tissues A Karolak, DA Markov, LJ McCawley, KA Rejniak Journal of The Royal Society Interface 15 (138), 20170703, 2018 | 119 | 2018 |
Morphophenotypic classification of tumor organoids as an indicator of drug exposure and penetration potential A Karolak, S Poonja, KA Rejniak PLOS Computational Biology 15 (7), e1007214, 2019 | 27 | 2019 |
Microenvironmental Niches and Sanctuaries: a Route to Acquired Resistance J Pérez-Velázquez, JL Gevertz, A Karolak, KA Rejniak Systems Biology of Tumor Microenvironment, Quantitative Modeling and Simulations, 2016 | 27 | 2016 |
Translation of AI into oncology clinical practice I El Naqa, A Karolak, Y Luo, L Folio, AA Tarhini, D Rollison, K Parodi Oncogene 42 (42), 3089-3097, 2023 | 19 | 2023 |
Micropharmacology: an in silico approach for assessing drug efficacy within a tumor tissue A Karolak, KA Rejniak Bulletin of mathematical biology 81 (9), 3623-3641, 2019 | 19 | 2019 |
Enhanced sampling simulations of DNA step parameters A Karolak, A van der Vaart Journal of Computational Chemistry 35 (32), 2297-2304, 2014 | 19 | 2014 |
Importance of local interactions for the stability of inhibitory helix 1 in apo Ets-1 A Karolak, A van der Vaart Biophysical chemistry 165, 74-78, 2012 | 18 | 2012 |
Targeting ligand specificity linked to tumor tissue topological heterogeneity via single-cell micro-pharmacological modeling A Karolak, VC Estrella, AS Huynh, T Chen, J Vagner, DL Morse, ... Scientific reports 8 (1), 3638, 2018 | 14 | 2018 |
Concepts and applications of information theory to immuno-oncology A Karolak, S Branciamore, JS McCune, PP Lee, AS Rodin, RC Rockne Trends in cancer 7 (4), 335-346, 2021 | 13 | 2021 |
Structure and properties of DOTA-chelated radiopharmaceuticals within the 225 Ac decay pathway AR Khabibullin, A Karolak, MM Budzevich, ML McLaughlin, DL Morse, ... Medchemcomm 9 (7), 1155-1163, 2018 | 13 | 2018 |
Molecular dynamics simulations of membrane-bound STIM1 to investigate conformational changes during STIM1 activation upon calcium release S Mukherjee, A Karolak, M Debant, P Buscaglia, Y Renaudineau, ... Journal of Chemical Information and Modeling 57 (2), 335-344, 2017 | 7 | 2017 |
Photoacoustic calorimetry study of ligand photorelease from the Ru (II) bis (2, 2′-bipyridine)(6, 6′-dimethyl-2, 2′-bipyridine) complex in aqueous solution TA Word, CL Whittington, A Karolak, MT Kemp, HL Woodcock, ... Chemical Physics Letters 619, 214-218, 2015 | 7 | 2015 |
From isothiocyanato–to silyl–nickel complexes H Maciejewski, B Marciniec, J Gulinski, A Karolak, NK Skvortsov Inorganic Chemistry Communications 5 (7), 464-467, 2002 | 7 | 2002 |
Pharmacometabonomic association of cyclophosphamide 4‐hydroxylation in hematopoietic cell transplant recipients JS McCune, R Nakamura, D O’Meally, TW Randolph, BM Sandmaier, ... Clinical and translational science 15 (5), 1215-1224, 2022 | 5 | 2022 |
Single-cell-based in silico models: a tool for dissecting tumor heterogeneity A Karolak, S Agrawal, S Lee, KA Rejniak Elsevier, 2019 | 5 | 2019 |
Towards personalized computational oncology: from spatial models of tumour spheroids, to organoids, to tissues. JR Soc Interface. 2018; 15 (138) A Karolak, DA Markov, LJ McCawley, KA Rejniak Epub 2018/01/26. doi: 10.1098/rsif. 2017.0703. PubMed PMID: 29367239, 2017 | 5 | 2017 |
BII stability and base step flexibility of N6-adenine methylated GATC motifs A Karolak, A van der Vaart Biophysical Chemistry 203, 22-27, 2015 | 5 | 2015 |
A framework for mutational signature analysis based on DNA shape parameters A Karolak, J Levatić, F Supek Plos one 17 (1), e0262495, 2022 | 4 | 2022 |
Mathematical modeling of tumor organoids: toward personalized medicine A Karolak, KA Rejniak Tumor organoids, 193-213, 2018 | 4 | 2018 |
Enhancing synergy of CAR T cell therapy and oncolytic virus therapy for pancreatic cancer R Walker, PE Navas, SH Friedman, S Galliani, A Karolak, F Macfarlane, ... bioRxiv, 055988, 2016 | 4 | 2016 |