Cereblon is a direct protein target for immunomodulatory and antiproliferative activities of lenalidomide and pomalidomide A Lopez-Girona, D Mendy, T Ito, K Miller, AK Gandhi, J Kang, S Karasawa, ... Leukemia 26 (11), 2326-2335, 2012 | 909 | 2012 |
A novel cereblon modulator recruits GSPT1 to the CRL4CRBN ubiquitin ligase ME Matyskiela, G Lu, T Ito, B Pagarigan, CC Lu, K Miller, W Fang, ... Nature 535 (7611), 252-257, 2016 | 575 | 2016 |
Structure of the human Cereblon–DDB1–lenalidomide complex reveals basis for responsiveness to thalidomide analogs PP Chamberlain, A Lopez-Girona, K Miller, G Carmel, B Pagarigan, ... Nature structural & molecular biology, 2014 | 554 | 2014 |
Measuring cereblon as a biomarker of response or resistance to lenalidomide and pomalidomide requires use of standardized reagents and understanding of gene complexity AK Gandhi, D Mendy, M Waldman, G Chen, E Rychak, K Miller, ... British journal of haematology 164 (2), 233-244, 2014 | 118 | 2014 |
A Dual Color Immunohistochemistry Assay for Measurement of Cereblon in Multiple Myeloma Patient Samples. Y Ren, M Wang, S Couto, DE Hansel, K Miller, A Lopez-Girona, ... Applied immunohistochemistry & molecular morphology: AIMM/official …, 2015 | 18 | 2015 |
Detection and quantification of cereblon protein and mRNA in multiple myeloma cell lines and primary CD138+ multiple myeloma cells AK Gandhi, H Avet-Loiseau, M Waldman, A Thakurta, SL Aukerman, ... ASH Annual Meeting Abstracts 120 (21), 4043, 2012 | 9 | 2012 |
Direct binding with cereblon mediates the antiproliferative and immunomodulatory action of lenalidomide and pomalidomide A Lopez-Girona, D Mendy, K Miller, AK Gandhi, J Kang, G Carmel, ... Blood 118 (21), 335-335, 2011 | 6 | 2011 |
The Novel mTOR Kinase Inhibitor CC-223 Demonstrates Significant Activity In In Vitro Models Of Multiple Myeloma (MM), Both As a Single Agent and In Combination With The … D Mendy, K Miller, J Leisten, RK Narla, HK Raymon, R Chopra, ... Blood 122 (21), 3160-3160, 2013 | 3 | 2013 |
Dual-Color CRBN/CD138 Immunohistochemistry Assay for Measuring Cereblon Protein in Samples from Patients with Multiple Myeloma Y Ren, M Wang, S Couta, D Hansel, K Miller, A Lopez-Girona, ... Blood 124 (21), 6021-6021, 2014 | | 2014 |