| Design of donecopride, a dual serotonin subtype 4 receptor agonist/acetylcholinesterase inhibitor with potential interest for Alzheimer's disease treatment C Lecoutey, D Hedou, T Freret, P Giannoni, F Gaven, M Since, V Bouet, ... Proceedings of the National Academy of Sciences 111 (36), E3825-E3830, 2014 | 118 | 2014 |
| Evaluation of the versatile character of a nanoemulsion formulation E Gué, M Since, S Ropars, R Herbinet, L Le Pluart, A Malzert-Fréon International Journal of Pharmaceutics 498 (1-2), 49-65, 2016 | 65 | 2016 |
| Pharmacotechnical development of a nasal drug delivery composite nanosystem intended for Alzheimer’s disease treatment T Adnet, AC Groo, C Picard, A Davis, S Corvaisier, M Since, F Bounoure, ... Pharmaceutics 12 (3), 251, 2020 | 50 | 2020 |
| Cyclic poly (α-peptoid) s by lithium bis (trimethylsilyl) amide (LiHMDS)-mediated ring-expansion polymerization: simple access to bioactive backbones P Salas-Ambrosio, A Tronnet, M Since, S Bourgeade-Delmas, JL Stigliani, ... Journal of the American Chemical Society 143 (10), 3697-3702, 2021 | 44 | 2021 |
| Nongenotoxic 3-Nitroimidazo[1,2-a]pyridines Are NTR1 Substrates That Display Potent in Vitro Antileishmanial Activity C Fersing, L Basmaciyan, C Boudot, J Pedron, S Hutter, A Cohen, ... ACS Medicinal Chemistry Letters 10 (1), 34-39, 2018 | 42 | 2018 |
| Inhibiting acetylcholinesterase to activate pleiotropic prodrugs with therapeutic interest in Alzheimer’s disease FX Toublet, C Lecoutey, J Lalut, B Hatat, A Davis, M Since, S Corvaisier, ... Molecules 24 (15), 2786, 2019 | 32 | 2019 |
| Original TDAE strategy using α-halocarbonyl derivatives M Since, T Terme, P Vanelle Tetrahedron 65 (31), 6128-6134, 2009 | 31 | 2009 |
| Pleiotropic prodrugs: Design of a dual butyrylcholinesterase inhibitor and 5-HT6 receptor antagonist with therapeutic interest in Alzheimer’s disease FX Toublet, J Lalut, B Hatat, C Lecoutey, A Davis, M Since, S Corvaisier, ... European Journal of Medicinal Chemistry 210, 113059, 2021 | 30 | 2021 |
| Malzert Fréon C Lecoutey, D Hedou, T Freret, P Giannoni, F Gaven, M Since, V Bouet, ... A., Mignani, S., Cresteil, T., Boulouard, M., Claeysen, S., Rochais, C …, 2014 | 29 | 2014 |
| Design, synthesis and biological evaluation of novel indano-and thiaindano-pyrazoles with potential interest for Alzheimer's disease D Genest, C Rochais, C Lecoutey, J Sopkova-de Oliveira Santos, ... MedChemComm 4 (6), 925-931, 2013 | 27 | 2013 |
| Comparison of 2 strategies to enhance pyridoclax solubility: Nanoemulsion delivery system versus salt synthesis AC Groo, M De Pascale, AS Voisin-Chiret, S Corvaisier, M Since, ... European Journal of Pharmaceutical Sciences 97, 218-226, 2017 | 23 | 2017 |
| 8-Alkynyl-3-nitroimidazopyridines display potent antitrypanosomal activity against both T. b. brucei and cruzi C Fersing, C Boudot, C Castera-Ducros, E Pinault, S Hutter, ... European Journal of Medicinal Chemistry 202, 112558, 2020 | 20 | 2020 |
| Novel benzylidenephenylpyrrolizinones with pleiotropic activities potentially useful in Alzheimer's disease treatment JP Jourdan, M Since, L El Kihel, C Lecoutey, S Corvaisier, R Legay, ... European Journal of Medicinal Chemistry 114, 365-379, 2016 | 20 | 2016 |
| Star-like poly (peptoid) s with selective antibacterial activity P Salas-Ambrosio, A Tronnet, M Badreldin, L Reyes, M Since, ... Polymer Chemistry 13 (5), 600-612, 2022 | 18 | 2022 |
| Pyridoclax-loaded nanoemulsion for enhanced anticancer effect on ovarian cancer AC Groo, S Hedir, M Since, E Brotin, LB Weiswald, H Paysant, G Nee, ... International Journal of Pharmaceutics 587, 119655, 2020 | 17 | 2020 |
| Novel multi target-directed ligands targeting 5-HT4 receptors with in cellulo antioxidant properties as promising leads in Alzheimer's disease C Lanthier, H Payan, I Liparulo, B Hatat, C Lecoutey, M Since, A Davis, ... European Journal of Medicinal Chemistry 182, 111596, 2019 | 15 | 2019 |
| Benzylphenylpyrrolizinones with Anti‐amyloid and Radical Scavenging Effects, Potentially Useful in Alzheimer's Disease Treatment JP Jourdan, M Since, L El Kihel, C Lecoutey, S Corvaisier, R Legay, ... ChemMedChem 12 (12), 913-916, 2017 | 14 | 2017 |
| A winning strategy to improve the anticancer properties of Cisplatin and Quercetin based on the nanoemulsions formulation J Ceramella, AC Groo, D Iacopetta, L Séguy, A Mariconda, F Puoci, ... Journal of Drug Delivery Science and Technology 66, 102907, 2021 | 13 | 2021 |
| Antikinetoplastid SAR study in 3-nitroimidazopyridine series: Identification of a novel non-genotoxic and potent anti-T. b. brucei hit-compound with improved pharmacokinetic … C Fersing, C Boudot, R Paoli-Lombardo, N Primas, E Pinault, S Hutter, ... European Journal of Medicinal Chemistry 206, 112668, 2020 | 13 | 2020 |
| New 8-Nitroquinolinone Derivative Displaying Submicromolar in Vitro Activities against Both Trypanosoma brucei and cruzi J Pedron, C Boudot, JY Brossas, E Pinault, S Bourgeade-Delmas, ... ACS Medicinal Chemistry Letters 11 (4), 464-472, 2020 | 13 | 2020 |
