| Recognition of RNA N 6-methyladenosine by IGF2BP proteins enhances mRNA stability and translation H Huang, H Weng, W Sun, X Qin, H Shi, H Wu, BS Zhao, A Mesquita, ... Nature cell biology 20 (3), 285-295, 2018 | 2080 | 2018 |
| FTO plays an oncogenic role in acute myeloid leukemia as a N6-methyladenosine RNA demethylase Z Li, H Weng, R Su, X Weng, Z Zuo, C Li, H Huang, S Nachtergaele, ... Cancer cell 31 (1), 127-141, 2017 | 1303 | 2017 |
| R-2HG exhibits anti-tumor activity by targeting FTO/m6A/MYC/CEBPA signaling R Su, L Dong, C Li, S Nachtergaele, M Wunderlich, Y Qing, X Deng, ... Cell 172 (1-2), 90-105. e23, 2018 | 900 | 2018 |
| METTL14 inhibits hematopoietic stem/progenitor differentiation and promotes leukemogenesis via mRNA m6A modification H Weng, H Huang, H Wu, X Qin, BS Zhao, L Dong, H Shi, J Skibbe, ... Cell stem cell 22 (2), 191-205. e9, 2018 | 844 | 2018 |
| Differential m6A, m6Am, and m1A demethylation mediated by FTO in the cell nucleus and cytoplasm J Wei, F Liu, Z Lu, Q Fei, Y Ai, PC He, H Shi, X Cui, R Su, A Klungland, ... Molecular cell 71 (6), 973-985. e5, 2018 | 637 | 2018 |
| Small-molecule targeting of oncogenic FTO demethylase in acute myeloid leukemia Y Huang, R Su, Y Sheng, L Dong, Z Dong, H Xu, T Ni, ZS Zhang, T Zhang, ... Cancer Cell 35 (4), 677-691. e10, 2019 | 631 | 2019 |
| RNA N 6-methyladenosine modification in cancers: current status and perspectives X Deng, R Su, H Weng, H Huang, Z Li, J Chen Cell research 28 (5), 507-517, 2018 | 629 | 2018 |
| Histone H3 trimethylation at lysine 36 guides m 6 A RNA modification co-transcriptionally H Huang, H Weng, K Zhou, T Wu, BS Zhao, M Sun, Z Chen, X Deng, ... Nature 567 (7748), 414-419, 2019 | 535 | 2019 |
| Targeting FTO suppresses cancer stem cell maintenance and immune evasion R Su, L Dong, Y Li, M Gao, L Han, M Wunderlich, X Deng, H Li, Y Huang, ... Cancer Cell 38 (1), 79-96. e11, 2020 | 501 | 2020 |
| RNA demethylase ALKBH5 selectively promotes tumorigenesis and cancer stem cell self-renewal in acute myeloid leukemia C Shen, Y Sheng, AC Zhu, S Robinson, X Jiang, L Dong, H Chen, R Su, ... Cell stem cell 27 (1), 64-80. e9, 2020 | 287 | 2020 |
| R-2-hydroxyglutarate attenuates aerobic glycolysis in leukemia by targeting the FTO/m6A/PFKP/LDHB axis Y Qing, L Dong, L Gao, C Li, Y Li, L Han, E Prince, B Tan, X Deng, ... Molecular Cell 81 (5), 922-939. e9, 2021 | 210 | 2021 |
| Role of N6-methyladenosine modification in cancer X Deng, R Su, X Feng, M Wei, J Chen Current opinion in genetics & development 48, 1-7, 2018 | 199 | 2018 |
| METTL16 exerts an m6A-independent function to facilitate translation and tumorigenesis R Su, L Dong, Y Li, M Gao, PC He, W Liu, J Wei, Z Zhao, L Gao, L Han, ... Nature cell biology 24 (2), 205-216, 2022 | 178 | 2022 |
| YTHDF1 promotes gastric carcinogenesis by controlling translation of FZD7 JY Jingnan Pi, Wen Wang, Ming Ji, Xiaoshuang Wang, Xueju Wei, Jing Jin, Tao ... Cancer Research, 2020 | 176* | 2020 |
| MiR-181 family: regulators of myeloid differentiation and acute myeloid leukemia as well as potential therapeutic targets R Su, HS Lin, XH Zhang, XL Yin, HM Ning, B Liu, PF Zhai, JN Gong, ... Oncogene 34 (25), 3226-3239, 2015 | 175 | 2015 |
| m6A RNA modifications are measured at single-base resolution across the mammalian transcriptome L Hu, S Liu, Y Peng, R Ge, R Su, C Senevirathne, BT Harada, Q Dai, ... Nature Biotechnology, 1-10, 2022 | 164 | 2022 |
| The role, mechanism and potentially therapeutic application of microRNA-29 family in acute myeloid leukemia JN Gong, J Yu, HS Lin, XH Zhang, XL Yin, Z Xiao, F Wang, XS Wang, ... Cell Death & Differentiation 21 (1), 100-112, 2014 | 125 | 2014 |
| Critical enzymatic functions of FTO in obesity and cancer X Deng, R Su, S Stanford, J Chen Frontiers in endocrinology 9, 396, 2018 | 124 | 2018 |
| Epitranscriptomics in liver disease: basic concepts and therapeutic potential Z Zhao, J Meng, R Su, J Zhang, J Chen, X Ma, Q Xia Journal of hepatology 73 (3), 664-679, 2020 | 115 | 2020 |
| FTO in cancer: functions, molecular mechanisms, and therapeutic implications Y Li, R Su, X Deng, Y Chen, J Chen Trends in Cancer, 2022 | 92 | 2022 |
Jianjun ChenBeckman Research Institute of City of Hope, University of Cincinnati, University of Chicago在 coh.org 的电子邮件经过验证
