Mitochondrial genome acquisition restores respiratory function and tumorigenic potential of cancer cells without mitochondrial DNA AS Tan, JW Baty, LF Dong, A Bezawork-Geleta, B Endaya, J Goodwin, ... Cell metabolism 21 (1), 81-94, 2015 | 722 | 2015 |
Mitochondrial complex II: at the crossroads A Bezawork-Geleta, J Rohlena, L Dong, K Pacak, J Neuzil Trends in biochemical sciences 42 (4), 312-325, 2017 | 271 | 2017 |
Horizontal transfer of whole mitochondria restores tumorigenic potential in mitochondrial DNA-deficient cancer cells LF Dong, J Kovarova, M Bajzikova, A Bezawork-Geleta, D Svec, ... eLife 6, e22187, 2017 | 261 | 2017 |
Reactivation of dihydroorotate dehydrogenase-driven pyrimidine biosynthesis restores tumor growth of respiration-deficient cancer cells M Bajzikova, J Kovarova, AR Coelho, S Boukalova, S Oh, K Rohlenova, ... Cell metabolism 29 (2), 399-416. e10, 2019 | 217 | 2019 |
AtnMat2, a nuclear-encoded maturase required for splicing of group-II introns in Arabidopsis mitochondria I Keren, A Bezawork-Geleta, M Kolton, I Maayan, E Belausov, M Levy, ... Rna 15 (12), 2299-2311, 2009 | 143 | 2009 |
Mitochondrial complex II, a novel target for anti-cancer agents K Kluckova, A Bezawork-Geleta, J Rohlena, L Dong, J Neuzil Biochimica et Biophysica Acta (BBA)-Bioenergetics 1827 (5), 552-564, 2013 | 138 | 2013 |
LON is the master protease that protects against protein aggregation in human mitochondria through direct degradation of misfolded proteins A Bezawork-Geleta, EJ Brodie, DA Dougan, KN Truscott Scientific reports 5, 17397, 2015 | 121 | 2015 |
Selective Disruption of Respiratory Supercomplexes as a New Strategy to Suppress Her2high Breast Cancer K Rohlenova, K Sachaphibulkij, J Stursa, A Bezawork-Geleta, J Blecha, ... Antioxidants & redox signaling 26 (2), 84-103, 2017 | 112 | 2017 |
Mitochondrially targeted vitamin E succinate efficiently kills breast tumour-initiating cells in a complex II-dependent manner B Yan, M Stantic, R Zobalova, A Bezawork-Geleta, M Stapelberg, J Stursa, ... BMC cancer 15 (1), 401, 2015 | 79 | 2015 |
Affinity purification of cell-specific mitochondria from whole animals resolves patterns of genetic mosaicism A Ahier, CY Dai, A Tweedie, A Bezawork-Geleta, I Kirmes, S Zuryn Nature cell biology 20 (3), 352-360, 2018 | 71 | 2018 |
Mitochondrial targeting of metformin enhances its activity against pancreatic cancer S Boukalova, J Stursa, L Werner, Z Ezrova, J Cerny, A Bezawork-Geleta, ... Molecular Cancer Therapeutics 15 (12), 2875-2886, 2016 | 69 | 2016 |
Alternative assembly of respiratory complex II connects energy stress to metabolic checkpoints A Bezawork-Geleta, H Wen, LF Dong, B Yan, J Vider, S Boukalova, ... Nature communications 9 (1), 1-17, 2018 | 55 | 2018 |
Mitochondrial matrix proteostasis is linked to hereditary paraganglioma: LON-mediated turnover of the human flavinylation factor SDH5 is regulated by its interaction with SDHA A Bezawork-Geleta, T Saiyed, DA Dougan, KN Truscott The FASEB Journal 28 (4), 1794-1804, 2014 | 47 | 2014 |
Unfolded protein responses in bacteria and mitochondria: a central role for the ClpXP machine KN Truscott, A Bezawork‐Geleta, DA Dougan IUBMB life 63 (11), 955-963, 2011 | 46 | 2011 |
Characterization of the molecular basis of group II intron RNA recognition by CRS1-CRM domains I Keren, L Klipcan, A Bezawork-Geleta, M Kolton, F Shaya, ... Journal of Biological Chemistry 283 (34), 23333-23342, 2008 | 44 | 2008 |
Characterisation of mesothelioma-initiating cells and their susceptibility to anti-cancer agents EA Pasdar, M Smits, M Stapelberg, M Bajzikova, M Stantic, J Goodwin, ... PloS one 10 (5), e0119549, 2015 | 30 | 2015 |
SMOC1 is a glucose-responsive hepatokine and therapeutic target for glycemic control MK Montgomery, J Bayliss, C Devereux, A Bezawork-Geleta, D Roberts, ... Science Translational Medicine 12 (559), 2020 | 28 | 2020 |
The assembly factor SDHAF2 is dispensable for flavination of the catalytic subunit of mitochondrial complex II in breast cancer cells A Bezawork-Geleta, L Dong, J Rohlena, J Neuzil Journal of Biological Chemistry 291 (41), 21414-21420, 2016 | 21 | 2016 |
The effect of mitochondrially targeted anticancer agents on mitochondrial (super) complexes M Vondrusova, A Bezawork-Geleta, K Sachaphibulkij, J Truksa, J Neuzil Mitochondrial Medicine, 195-208, 2015 | 14 | 2015 |
Lipid droplets and ferroptosis as new players in brain cancer glioblastoma progression and therapeutic resistance A Bezawork-Geleta, J Dimou, MJ Watt Frontiers in Oncology 12, 2022 | 13 | 2022 |