EZH2 generates a methyl degron that is recognized by the DCAF1/DDB1/CUL4 E3 ubiquitin ligase complex JM Lee, JS Lee, H Kim, K Kim, H Park, JY Kim, SH Lee, IS Kim, J Kim, ... Molecular cell 48 (4), 572-586, 2012 | 267 | 2012 |
RORα attenuates Wnt/β-catenin signaling by PKCα-dependent phosphorylation in colon cancer JM Lee, IS Kim, H Kim, JS Lee, K Kim, HY Yim, J Jeong, JH Kim, JY Kim, ... Molecular cell 37 (2), 183-195, 2010 | 236 | 2010 |
Control of protein stability by post-translational modifications JM Lee, HM Hammarén, MM Savitski, SH Baek Nature Communications 14 (1), 201, 2023 | 228 | 2023 |
Negative regulation of hypoxic responses via induced Reptin methylation JS Lee, Y Kim, IS Kim, B Kim, HJ Choi, JM Lee, HJR Shin, JH Kim, JY Kim, ... Molecular cell 39 (1), 71-85, 2010 | 194 | 2010 |
Roles of sumoylation of a reptin chromatin-remodelling complex in cancer metastasis JH Kim, HJ Choi, B Kim, MH Kim, JM Lee, IS Kim, MH Lee, SJ Choi, ... Nature cell biology 8 (6), 631-639, 2006 | 191 | 2006 |
DNA damage-induced RORα is crucial for p53 stabilization and increased apoptosis H Kim, JM Lee, G Lee, J Bhin, SK Oh, K Kim, KE Pyo, JS Lee, HY Yim, ... Molecular cell 44 (5), 797-810, 2011 | 90 | 2011 |
SUMOylation of pontin chromatin-remodeling complex reveals a signal integration code in prostate cancer cells JH Kim, JM Lee, HJ Nam, HJ Choi, JW Yang, JS Lee, MH Kim, SI Kim, ... Proceedings of the National Academy of Sciences 104 (52), 20793-20798, 2007 | 83 | 2007 |
Cbl-independent degradation of Met: ways to avoid agonism of bivalent Met-targeting antibody JM Lee, B Kim, SB Lee, Y Jeong, YM Oh, YJ Song, S Jung, J Choi, S Lee, ... Oncogene 33 (1), 34-43, 2014 | 71 | 2014 |
Gastrointestinal malignancies harbor actionable MET exon 14 deletions J Lee, SHI Ou, JM Lee, HC Kim, M Hong, SY Kim, J Jang, S Ahn, SY Kang, ... Oncotarget 6 (29), 28211, 2015 | 68 | 2015 |
RORα is crucial for attenuated inflammatory response to maintain intestinal homeostasis SK Oh, D Kim, K Kim, K Boo, YS Yu, IS Kim, Y Jeon, SK Im, SH Lee, ... Proceedings of the National Academy of Sciences 116 (42), 21140-21149, 2019 | 66 | 2019 |
SUMOylation of RORα potentiates transcriptional activation function EJ Hwang, JM Lee, J Jeong, JH Park, Y Yang, JS Lim, JH Kim, SH Baek, ... Biochemical and biophysical research communications 378 (3), 513-517, 2009 | 62 | 2009 |
Bcl3-dependent stabilization of CtBP1 is crucial for the inhibition of apoptosis and tumor progression in breast cancer HJ Choi, JM Lee, H Kim, HJ Nam, HJR Shin, D Kim, E Ko, DY Noh, KI Kim, ... Biochemical and biophysical research communications 400 (3), 396-402, 2010 | 56 | 2010 |
The hidden switches underlying RORα-mediated circuits that critically regulate uncontrolled cell proliferation D Shin, IS Kim, JM Lee, SY Shin, JH Lee, SH Baek, KH Cho Journal of Molecular Cell Biology 6 (4), 338-348, 2014 | 44 | 2014 |
RORα Regulates Cholesterol Metabolism of CD8+ T Cells for Anticancer Immunity IK Lee, H Song, H Kim, IS Kim, NL Tran, SH Kim, SJ Oh, JM Lee Cancers 12 (7), 1733, 2020 | 42 | 2020 |
Synthetic lethal screening reveals FGFR as one of the combinatorial targets to overcome resistance to Met-targeted therapy B Kim, S Wang, JM Lee, Y Jeong, T Ahn, DS Son, HW Park, HS Yoo, ... Oncogene 34 (9), 1083-1093, 2015 | 40 | 2015 |
Unraveling the physiological roles of retinoic acid receptor-related orphan receptor α JM Lee, H Kim, SH Baek Experimental & molecular medicine 53 (9), 1278-1286, 2021 | 31 | 2021 |
Novel strategy for a bispecific antibody: induction of dual target internalization and degradation JM Lee, SH Lee, JW Hwang, SJ Oh, B Kim, S Jung, SH Shim, PW Lin, ... Oncogene 35 (34), 4437-4446, 2016 | 31 | 2016 |
USP8 modulates ubiquitination of LRIG1 for Met degradation YM Oh, SB Lee, J Choi, HY Suh, S Shim, YJ Song, B Kim, JM Lee, SJ Oh, ... Scientific Reports 4 (1), 4980, 2014 | 30 | 2014 |
The chromatin-binding protein PHF6 functions as an E3 ubiquitin ligase of H2BK120 via H2BK12Ac recognition for activation of trophectodermal genes S Oh, K Boo, J Kim, SA Baek, Y Jeon, J You, H Lee, HJ Choi, D Park, ... Nucleic acids research 48 (16), 9037-9052, 2020 | 26 | 2020 |
A new anti-c-Met antibody selected by a mechanism-based dual-screening method: therapeutic potential in cancer YM Oh, YJ Song, SB Lee, Y Jeong, B Kim, GW Kim, KE Kim, JM Lee, ... Molecules and cells 34, 523-529, 2012 | 26 | 2012 |