Mitochondrial reprogramming underlies resistance to BCL-2 inhibition in lymphoid malignancies R Guièze, VM Liu, D Rosebrock, AA Jourdain, M Hernández-Sánchez, ... Cancer cell 36 (4), 369-384. e13, 2019 | 286 | 2019 |
Prognostic impact and landscape of NOTCH1 mutations in chronic lymphocytic leukemia (CLL): a study on 852 patients S Weissmann, A Roller, S Jeromin, M Hernandez, M Abaigar, ... Leukemia 27 (12), 2393-2396, 2013 | 88 | 2013 |
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Patients with chronic lymphocytic leukemia and complex karyotype show an adverse outcome even in absence of TP53/ATM FISH deletions A Puiggros, R Collado, M Calasanz, M Ortega, N Ruiz-Xiville, ... Impact Journals, 2017 | 63 | 2017 |
Next-generation sequencing and FISH studies reveal the appearance of gene mutations and chromosomal abnormalities in hematopoietic progenitors in chronic lymphocytic leukemia M Quijada-Álamo, M Hernández-Sánchez, C Robledo, ... Journal of hematology & oncology 10, 1-11, 2017 | 52 | 2017 |
The CRISPR/Cas9 system efficiently reverts the tumorigenic ability of BCR/ABL in vitro and in a xenograft model of chronic myeloid leukemia I García-Tuñón, M Hernández-Sánchez, JL Ordoñez, V Alonso-Pérez, ... Oncotarget 8 (16), 26027, 2017 | 46 | 2017 |
Mutations in TP53 and JAK2 are independent prognostic biomarkers in B-cell precursor acute lymphoblastic leukaemia M Forero-Castro, C Robledo, R Benito, I Bodega-Mayor, I Rapado, ... British journal of cancer 117 (2), 256-265, 2017 | 43 | 2017 |
Next-generation sequencing in chronic lymphocytic leukemia: recent findings and new horizons AE Rodríguez-Vicente, V Bikos, M Hernández-Sánchez, J Malcikova, ... Impact Journals, 2017 | 43 | 2017 |
Different prognostic impact of recurrent gene mutations in chronic lymphocytic leukemia depending on IGHV gene somatic hypermutation status: a study by ERIC in HARMONY L Mansouri, B Thorvaldsdottir, LA Sutton, G Karakatsoulis, ... Leukemia 37 (2), 339-347, 2023 | 42 | 2023 |
A low frequency of losses in 11q chromosome is associated with better outcome and lower rate of genomic mutations in patients with chronic lymphocytic leukemia JÁ Hernández, M Hernández-Sánchez, AE Rodríguez-Vicente, ... PLoS One 10 (11), e0143073, 2015 | 33 | 2015 |
CRISPR/Cas9-generated models uncover therapeutic vulnerabilities of del (11q) CLL cells to dual BCR and PARP inhibition M Quijada-Álamo, M Hernández-Sánchez, V Alonso-Pérez, ... Leukemia 34 (6), 1599-1612, 2020 | 32 | 2020 |
Deregulation of genes related to iron and mitochondrial metabolism in refractory anemia with ring sideroblasts M del Rey, R Benito, C Fontanillo, FJ Campos-Laborie, K Janusz, ... PLoS One 10 (5), e0126555, 2015 | 32 | 2015 |
Chronic lymphocytic leukemia patients with IGH translocations are characterized by a distinct genetic landscape with prognostic implications C Pérez‐Carretero, M Hernández‐Sánchez, T González, ... International Journal of Cancer 147 (10), 2780-2792, 2020 | 31 | 2020 |
The International Prognostic Index for Patients with Chronic Lymphocytic Leukemia Has the Higher Value in Predicting Overall Outcome Compared with the Barcelona‐Brno Biomarkers … C Muñoz-Novas, M Poza-Santaella, I González-Gascón y Marín, ... BioMed Research International 2018 (1), 9506979, 2018 | 30 | 2018 |
A high proportion of cells carrying trisomy 12 is associated with a worse outcome in patients with chronic lymphocytic leukemia I González‐Gascón y Marín, M Hernández‐Sánchez, ... Hematological Oncology 34 (2), 84-92, 2016 | 30 | 2016 |
High throughput single-cell detection of multiplex CRISPR-edited gene modifications E Ten Hacken, K Clement, S Li, M Hernández-Sánchez, R Redd, S Wang, ... Genome biology 21, 1-11, 2020 | 28 | 2020 |
The evolving landscape of chronic lymphocytic leukemia on diagnosis, prognosis and treatment C Pérez-Carretero, I Gonzalez-Gascon-y-Marin, AE Rodriguez-Vicente, ... Diagnostics 11 (5), 853, 2021 | 27 | 2021 |
The presence of genomic imbalances is associated with poor outcome in patients with burkitt lymphoma treated with dose‐intensive chemotherapy including rituximab M Forero‐Castro, C Robledo, E Lumbreras, R Benito, ... British journal of haematology 172 (3), 428-438, 2016 | 26 | 2016 |
MicroRNA-223 is a novel negative regulator of HSP90B1 in CLL AE Rodríguez-Vicente, D Quwaider, R Benito, I Misiewicz-Krzeminska, ... BMC cancer 15, 1-9, 2015 | 24 | 2015 |
From biomarkers to models in the changing landscape of chronic lymphocytic leukemia: Evolve or become extinct I González-Gascón-y-Marín, C Muñoz-Novas, AE Rodríguez-Vicente, ... Cancers 13 (8), 1782, 2021 | 22 | 2021 |