| Genetically altered expression of spermidine/spermine N1-acetyltransferase affects fat metabolism in mice via acetyl-CoA J Jell, S Merali, ML Hensen, R Mazurchuk, JA Spernyak, P Diegelman, ... Journal of Biological Chemistry 282 (11), 8404-8413, 2007 | 156 | 2007 |
| Peroxiredoxin 1 controls prostate cancer growth through Toll-like receptor 4–dependent regulation of tumor vasculature JR Riddell, W Bshara, MT Moser, JA Spernyak, BA Foster, SO Gollnick Cancer research 71 (5), 1637-1646, 2011 | 153 | 2011 |
| Iron (II) paraCEST MRI contrast agents SJ Dorazio, PB Tsitovich, KE Siters, JA Spernyak, JR Morrow Journal of the American Chemical Society 133 (36), 14154-14156, 2011 | 145 | 2011 |
| Mild elevation of body temperature reduces tumor interstitial fluid pressure and hypoxia and enhances efficacy of radiotherapy in murine tumor models A Sen, ML Capitano, JA Spernyak, JT Schueckler, S Thomas, AK Singh, ... Cancer research 71 (11), 3872-3880, 2011 | 137 | 2011 |
| A redox-activated MRI contrast agent that switches between paramagnetic and diamagnetic states PB Tsitovich, JA Spernyak, JR Morrow Angewandte Chemie (International ed. in English) 52 (52), 13997, 2013 | 113 | 2013 |
| The NiCEST approach: nickel (II) paraCEST MRI contrast agents AO Olatunde, SJ Dorazio, JA Spernyak, JR Morrow Journal of the American Chemical Society 134 (45), 18503-18505, 2012 | 102 | 2012 |
| CoCEST: cobalt (II) amide-appended paraCEST MRI contrast agents SJ Dorazio, AO Olatunde, JA Spernyak, JR Morrow Chemical Communications 49 (85), 10025-10027, 2013 | 97 | 2013 |
| Chlorophyll-a analogues conjugated with aminobenzyl-DTPA as potential bifunctional agents for magnetic resonance imaging and photodynamic therapy G Li, A Slansky, MP Dobhal, LN Goswami, A Graham, Y Chen, P Kanter, ... Bioconjugate chemistry 16 (1), 32-42, 2005 | 87 | 2005 |
| Light delivery over extended time periods enhances the effectiveness of photodynamic therapy M Seshadri, DA Bellnier, LA Vaughan, JA Spernyak, R Mazurchuk, ... Clinical Cancer Research 14 (9), 2796-2805, 2008 | 86 | 2008 |
| A Class of FeIII Macrocyclic Complexes with Alcohol Donor Groups as Effective T1 MRI Contrast Agents EM Snyder, D Asik, SM Abozeid, A Burgio, G Bateman, SG Turowski, ... Angewandte Chemie 132 (6), 2435-2440, 2020 | 79 | 2020 |
| Tumor vascular response to photodynamic therapy and the antivascular agent 5, 6-dimethylxanthenone-4-acetic acid: implications for combination therapy M Seshadri, JA Spernyak, R Mazurchuk, SH Camacho, AR Oseroff, ... Clinical cancer research 11 (11), 4241-4250, 2005 | 77 | 2005 |
| Metabolic imaging of rat brain during pharmacologically-induced tinnitus AK Paul, E Lobarinas, R Simmons, D Wack, JC Luisi, J Spernyak, ... Neuroimage 44 (2), 312-318, 2009 | 76 | 2009 |
| High correlation of whole-body red fluorescent protein imaging and magnetic resonance imaging on an orthotopic model of pancreatic cancer M Bouvet, J Spernyak, MH Katz, RV Mazurchuk, S Takimoto, R Bernacki, ... Cancer research 65 (21), 9829-9833, 2005 | 72 | 2005 |
| Fast stereolithography printing of large‐scale biocompatible hydrogel models N Anandakrishnan, H Ye, Z Guo, Z Chen, KI Mentkowski, JK Lang, ... Advanced healthcare materials 10 (10), 2002103, 2021 | 71 | 2021 |
| Lack of microvessels in well-differentiated regions of human head and neck squamous cell carcinoma A253 associated with functional magnetic resonance imaging detectable hypoxia … A Bhattacharya, K Tóth, R Mazurchuk, JA Spernyak, HK Slocum, ... Clinical cancer research 10 (23), 8005-8017, 2004 | 63 | 2004 |
| Gear up for a pH shift: A responsive iron (II) 2-amino-6-picolyl-appended macrocyclic paracest agent that protonates at a pendent group PB Tsitovich, JM Cox, JA Spernyak, JR Morrow Inorganic chemistry 55 (22), 12001-12010, 2016 | 58 | 2016 |
| Multifunctional Liposomes for Image‐Guided Intratumoral Chemo‐Phototherapy D Miranda, K Carter, D Luo, S Shao, J Geng, C Li, U Chitgupi, ... Advanced healthcare materials 6 (16), 1700253, 2017 | 56 | 2017 |
| Seven-Coordinate CoII, FeII and Six-Coordinate NiII Amide-Appended Macrocyclic Complexes as ParaCEST Agents in Biological Media AO Olatunde, JM Cox, MD Daddario, JA Spernyak, JB Benedict, ... Inorganic Chemistry 53 (16), 8311-8321, 2014 | 56 | 2014 |
| Six, Seven or Eight Coordinate FeII, CoII or NiII Complexes of Amide‐Appended Tetraazamacrocycles for ParaCEST Thermometry AO Olatunde, CJ Bond, SJ Dorazio, JM Cox, JB Benedict, MD Daddario, ... Chemistry–A European Journal 21 (50), 18290-18300, 2015 | 55 | 2015 |
| Hexylether derivative of pyropheophorbide-a (HPPH) on conjugating with 3gadolinium (III) aminobenzyldiethylenetriaminepentaacetic acid shows potential for in vivo tumor imaging … JA Spernyak, WH White III, M Ethirajan, NJ Patel, L Goswami, Y Chen, ... Bioconjugate chemistry 21 (5), 828-835, 2010 | 53 | 2010 |
