Highly efficient and selective phosphorylation of amino acid derivatives and polyols catalysed by 2-aryl-4-(dimethylamino) pyridine-N-oxides–towards kinase-like reactivity JI Murray, R Woscholski, AC Spivey Chemical Communications 50 (88), 13608-13611, 2014 | 58 | 2014 |
Catalytic, enantio-and diastereoselective synthesis of γ-butyrolactones incorporating quaternary stereocentres F Manoni, C Cornaggia, J Murray, S Tallon, SJ Connon Chemical Communications 48 (52), 6502-6504, 2012 | 56 | 2012 |
Kinetic Resolution of 2‐Substituted Indolines by N‐Sulfonylation using an Atropisomeric 4‐DMAP‐N‐oxide Organocatalyst JI Murray, NJ Flodén, A Bauer, ND Fessner, DL Dunklemann, ... Angewandte Chemie 129 (21), 5854-5858, 2017 | 51 | 2017 |
Highly modular synthesis of 1, 2-diketones via multicomponent coupling reactions of isocyanides as CO equivalents AM Dechert-Schmitt, MR Garnsey, HM Wisniewska, JI Murray, T Lee, ... ACS Catalysis 9 (5), 4508-4515, 2019 | 42 | 2019 |
Amines vs. N‐Oxides as Organocatalysts for Acylation, Sulfonylation and Silylation of Alcohols: 1‐Methylimidazole N‐Oxide as an Efficient Catalyst for Silylation of … JI Murray, AC Spivey Advanced Synthesis & Catalysis 357 (18), 3825-3830, 2015 | 38 | 2015 |
Organocatalytic phosphorylation of alcohols using pyridine-N-oxide JI Murray, R Woscholski, AC Spivey Synlett 26 (07), 985-990, 2015 | 34 | 2015 |
Isotopically directed symmetry breaking and enantioenrichment in attrition-enhanced deracemization JI Murray, JN Sanders, PF Richardson, KN Houk, DG Blackmond Journal of the American Chemical Society 142 (8), 3873-3879, 2020 | 21 | 2020 |
Ipso Nitration of Aryl Boronic Acids Using Fuming Nitric Acid JI Murray, MV Silva Elipe, KD Baucom, DB Brown, K Quasdorf, S Caille The Journal of Organic Chemistry 87 (4), 1977-1985, 2021 | 18 | 2021 |
Kinetic investigations to enable development of a robust radical benzylic bromination for commercial manufacturing of AMG 423 dihydrochloride hydrate JI Murray, MV Silva Elipe, A Cosbie, K Baucom, K Quasdorf, S Caille Organic Process Research & Development 24 (8), 1523-1530, 2020 | 17 | 2020 |
Kinetic and Mechanistic Investigations to Enable a Key Suzuki Coupling for Sotorasib Manufacture─ What a Difference a Base Makes JI Murray, L Zhang, A Simon, MV Silva Elipe, CS Wei, S Caille, ... Organic Process Research & Development 27 (1), 198-205, 2022 | 15 | 2022 |
Development of a continuous photochemical bromination/alkylation sequence en route to AMG 423 K Quasdorf, JI Murray, H Nguyen, MV Silva Elipe, A Ericson, E Kircher, ... Organic Process Research & Development 26 (2), 458-466, 2022 | 13 | 2022 |
Hazard evaluation and safety considerations for scale-up of a fuming nitric acid mediated nitration of aryl boronic acids JI Murray, DB Brown, MV Silva Elipe, S Caille Organic Process Research & Development 26 (3), 657-660, 2021 | 13 | 2021 |
AC Spivey in Lewis Base Catalysis in Organic Synthesis Vol. 2 JI Murray, Z Heckenast Wiley-VCH, Weinheim, 2016 | 12 | 2016 |
Synthesis of omecamtiv mecarbil S Caille, J Murray, K Quasdorf, H Nguyen, MVS ELIPE, AE Ericson US Patent 11,702,380, 2023 | 6 | 2023 |
Synthesis of Substituted Pyridines via Formal (3+ 3) Cycloaddition of Enamines with Unsaturated Aldehydes and Ketones XJ Dai, P Krolikowski, JI Murray, CS Wei, PK Dornan, AR Rotheli, S Caille, ... The Journal of Organic Chemistry 87 (13), 8437-8444, 2022 | 6 | 2022 |
Preparation of 1-methylimidazole-N-oxide (NMI-O) JI Murray, AC Spivey Org. Synth 93, 331-340, 2016 | 6 | 2016 |
A Continuous Process for Manufacturing Apremilast. Part I: Process Development and Intensification by Utilizing Flow Chemistry Principles HW Hsieh, CM Cohen, DJ Griffin, P Ananthoji, NH Avci, DB Brown, ... Organic Process Research & Development 28 (5), 1369-1384, 2024 | 5 | 2024 |
Liquid/liquid heterogeneous reaction monitoring: Insights into biphasic Suzuki-Miyaura cross-coupling Y Sato, J Liu, IE Ndukwe, MVS Elipe, DJ Griffin, JI Murray, JE Hein Chem Catalysis 3 (7), 2023 | 4 | 2023 |
Chiral Lewis Base Activation of Acyl and Related Donors in Enantioselective Transformations (n?→?π*) JI Murray, Z Heckenast, AC Spivey Lewis Base Catalysis in Organic Synthesis, 457-526, 2016 | 4 | 2016 |
A Continuous Process for Manufacturing Apremilast. Part II: Process Characterization to Establish a Parametric Control Strategy DJ Griffin, HW Hsieh, NH Avci, N Sarkar, JD Fostinis, N Klitzing, JI Murray, ... Organic Process Research & Development, 2024 | 3 | 2024 |