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James I. Murray
James I. Murray
在 amgen.com 的电子邮件经过验证
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引用次数
引用次数
年份
Highly efficient and selective phosphorylation of amino acid derivatives and polyols catalysed by 2-aryl-4-(dimethylamino) pyridine-N-oxides–towards kinase-like reactivity
JI Murray, R Woscholski, AC Spivey
Chemical Communications 50 (88), 13608-13611, 2014
582014
Catalytic, enantio-and diastereoselective synthesis of γ-butyrolactones incorporating quaternary stereocentres
F Manoni, C Cornaggia, J Murray, S Tallon, SJ Connon
Chemical Communications 48 (52), 6502-6504, 2012
562012
Kinetic Resolution of 2‐Substituted Indolines by N‐Sulfonylation using an Atropisomeric 4‐DMAP‐N‐oxide Organocatalyst
JI Murray, NJ Flodén, A Bauer, ND Fessner, DL Dunklemann, ...
Angewandte Chemie 129 (21), 5854-5858, 2017
512017
Highly modular synthesis of 1, 2-diketones via multicomponent coupling reactions of isocyanides as CO equivalents
AM Dechert-Schmitt, MR Garnsey, HM Wisniewska, JI Murray, T Lee, ...
ACS Catalysis 9 (5), 4508-4515, 2019
422019
Amines vs. N‐Oxides as Organocatalysts for Acylation, Sulfonylation and Silylation of Alcohols: 1‐Methylimidazole N‐Oxide as an Efficient Catalyst for Silylation of …
JI Murray, AC Spivey
Advanced Synthesis & Catalysis 357 (18), 3825-3830, 2015
382015
Organocatalytic phosphorylation of alcohols using pyridine-N-oxide
JI Murray, R Woscholski, AC Spivey
Synlett 26 (07), 985-990, 2015
342015
Isotopically directed symmetry breaking and enantioenrichment in attrition-enhanced deracemization
JI Murray, JN Sanders, PF Richardson, KN Houk, DG Blackmond
Journal of the American Chemical Society 142 (8), 3873-3879, 2020
212020
Ipso Nitration of Aryl Boronic Acids Using Fuming Nitric Acid
JI Murray, MV Silva Elipe, KD Baucom, DB Brown, K Quasdorf, S Caille
The Journal of Organic Chemistry 87 (4), 1977-1985, 2021
182021
Kinetic investigations to enable development of a robust radical benzylic bromination for commercial manufacturing of AMG 423 dihydrochloride hydrate
JI Murray, MV Silva Elipe, A Cosbie, K Baucom, K Quasdorf, S Caille
Organic Process Research & Development 24 (8), 1523-1530, 2020
172020
Kinetic and Mechanistic Investigations to Enable a Key Suzuki Coupling for Sotorasib Manufacture─ What a Difference a Base Makes
JI Murray, L Zhang, A Simon, MV Silva Elipe, CS Wei, S Caille, ...
Organic Process Research & Development 27 (1), 198-205, 2022
152022
Development of a continuous photochemical bromination/alkylation sequence en route to AMG 423
K Quasdorf, JI Murray, H Nguyen, MV Silva Elipe, A Ericson, E Kircher, ...
Organic Process Research & Development 26 (2), 458-466, 2022
132022
Hazard evaluation and safety considerations for scale-up of a fuming nitric acid mediated nitration of aryl boronic acids
JI Murray, DB Brown, MV Silva Elipe, S Caille
Organic Process Research & Development 26 (3), 657-660, 2021
132021
AC Spivey in Lewis Base Catalysis in Organic Synthesis Vol. 2
JI Murray, Z Heckenast
Wiley-VCH, Weinheim, 2016
122016
Synthesis of omecamtiv mecarbil
S Caille, J Murray, K Quasdorf, H Nguyen, MVS ELIPE, AE Ericson
US Patent 11,702,380, 2023
62023
Synthesis of Substituted Pyridines via Formal (3+ 3) Cycloaddition of Enamines with Unsaturated Aldehydes and Ketones
XJ Dai, P Krolikowski, JI Murray, CS Wei, PK Dornan, AR Rotheli, S Caille, ...
The Journal of Organic Chemistry 87 (13), 8437-8444, 2022
62022
Preparation of 1-methylimidazole-N-oxide (NMI-O)
JI Murray, AC Spivey
Org. Synth 93, 331-340, 2016
62016
A Continuous Process for Manufacturing Apremilast. Part I: Process Development and Intensification by Utilizing Flow Chemistry Principles
HW Hsieh, CM Cohen, DJ Griffin, P Ananthoji, NH Avci, DB Brown, ...
Organic Process Research & Development 28 (5), 1369-1384, 2024
52024
Liquid/liquid heterogeneous reaction monitoring: Insights into biphasic Suzuki-Miyaura cross-coupling
Y Sato, J Liu, IE Ndukwe, MVS Elipe, DJ Griffin, JI Murray, JE Hein
Chem Catalysis 3 (7), 2023
42023
Chiral Lewis Base Activation of Acyl and Related Donors in Enantioselective Transformations (n?→?π*)
JI Murray, Z Heckenast, AC Spivey
Lewis Base Catalysis in Organic Synthesis, 457-526, 2016
42016
A Continuous Process for Manufacturing Apremilast. Part II: Process Characterization to Establish a Parametric Control Strategy
DJ Griffin, HW Hsieh, NH Avci, N Sarkar, JD Fostinis, N Klitzing, JI Murray, ...
Organic Process Research & Development, 2024
32024
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