关注
Zhenhua Chen
Zhenhua Chen
其他姓名Zhen-Hua Chen
Staff Scientist, City of Hope
在 coh.org 的电子邮件经过验证
标题
引用次数
引用次数
年份
Histone H3 trimethylation at lysine 36 guides m6A RNA modification co-transcriptionally
H Huang, H Weng, K Zhou, T Wu, BS Zhao, M Sun, Z Chen, X Deng, ...
Nature 567 (7748), 414-419, 2019
5472019
Targeting FTO suppresses cancer stem cell maintenance and immune evasion
R Su, L Dong, Y Li, M Gao, L Han, M Wunderlich, X Deng, H Li, Y Huang, ...
Cancer cell 38 (1), 79-96. e11, 2020
5222020
Long non-coding RNA: a new player in cancer
H Zhang, Z Chen, X Wang, Z Huang, Z He, Y Chen
Journal of hematology & oncology 6, 1-7, 2013
4732013
LncRNAs H19 and HULC, activated by oxidative stress, promote cell migration and invasion in cholangiocarcinoma through a ceRNA manner
WT Wang, H Ye, PP Wei, BW Han, B He, ZH Chen, YQ Chen
Journal of hematology & oncology 9, 1-12, 2016
2292016
R-2-hydroxyglutarate attenuates aerobic glycolysis in leukemia by targeting the FTO/m6A/PFKP/LDHB axis
Y Qing, L Dong, L Gao, C Li, Y Li, L Han, E Prince, B Tan, X Deng, ...
Molecular cell 81 (5), 922-939. e9, 2021
2212021
The lncRNA HOTAIRM1 regulates the degradation of PML-RARA oncoprotein and myeloid cell differentiation by enhancing the autophagy pathway
ZH Chen, WT Wang, W Huang, K Fang, YM Sun, SR Liu, XQ Luo, ...
Cell Death & Differentiation 24 (2), 212-224, 2017
2012017
METTL16 exerts an m6A-independent function to facilitate translation and tumorigenesis
R Su, L Dong, Y Li, M Gao, PC He, W Liu, J Wei, Z Zhao, L Gao, L Han, ...
Nature cell biology 24 (2), 205-216, 2022
1932022
LncRNA ANRIL regulates AML development through modulating the glucose metabolism pathway of AdipoR1/AMPK/SIRT1
LY Sun, XJ Li, YM Sun, W Huang, K Fang, C Han, ZH Chen, XQ Luo, ...
Molecular cancer 17, 1-6, 2018
1372018
The m(6)A reader IGF2BP2 regulates glutamine metabolism and represents a therapeutic target in acute myeloid leukemia
Cancer cell, 2022
1272022
The RNA m6A reader YTHDF2 controls NK cell antitumor and antiviral immunity
S Ma, J Yan, T Barr, J Zhang, Z Chen, LS Wang, JC Sun, J Chen, ...
Journal of Experimental Medicine 218 (8), e20210279, 2021
1212021
A distinct set of long non-coding RNAs in childhood MLL-rearranged acute lymphoblastic leukemia: biology and epigenetic target
K Fang, BW Han, ZH Chen, KY Lin, CW Zeng, XJ Li, JH Li, XQ Luo, ...
Human molecular genetics 23 (12), 3278-3288, 2014
592014
circRNA circAF4 functions as an oncogene to regulate MLL-AF4 fusion protein expression and inhibit MLL leukemia progression
W Huang, K Fang, TQ Chen, ZC Zeng, YM Sun, C Han, LY Sun, ZH Chen, ...
Journal of hematology & oncology 12, 1-13, 2019
572019
METTL16 drives leukemogenesis and leukemia stem cell self-renewal by reprogramming BCAA metabolism
L Han, L Dong, K Leung, Z Zhao, Y Li, L Gao, Z Chen, J Xue, Y Qing, W Li, ...
Cell Stem Cell 30 (1), 52-68. e13, 2023
532023
MIR-708 promotes phagocytosis to eradicate T-ALL cells by targeting CD47
W Huang, WT Wang, K Fang, ZH Chen, YM Sun, C Han, LY Sun, XQ Luo, ...
Molecular cancer 17, 1-6, 2018
532018
MIR125B1 represses the degradation of the PML-RARA oncoprotein by an autophagy-lysosomal pathway in acute promyelocytic leukemia
CW Zeng, ZH Chen, XJ Zhang, BW Han, KY Lin, XJ Li, PP Wei, H Zhang, ...
Autophagy 10 (10), 1726-1737, 2014
512014
Activation of the lysosome-associated membrane protein LAMP5 by DOT1L serves as a bodyguard for MLL fusion oncoproteins to evade degradation in leukemia
WT Wang, C Han, YM Sun, ZH Chen, K Fang, W Huang, LY Sun, ZC Zeng, ...
Clinical Cancer Research 25 (9), 2795-2808, 2019
492019
Nuclear export of chimeric mRNAs depends on an lncRNA-triggered autoregulatory loop in blood malignancies
ZH Chen, TQ Chen, ZC Zeng, D Wang, C Han, YM Sun, W Huang, LY Sun, ...
Cell Death & Disease 11 (7), 566, 2020
352020
RNA N6-methyladenosine reader YTHDC1 is essential for TGF-beta-mediated metastasis of triple negative breast cancer
B Tan, K Zhou, W Liu, E Prince, Y Qing, Y Li, L Han, X Qin, R Su, ...
Theranostics 12 (13), 5727, 2022
262022
Global identification and characterization of lncRNAs that control inflammation in malignant cholangiocytes
BW Han, H Ye, PP Wei, B He, C Han, ZH Chen, YQ Chen, WT Wang
BMC genomics 19, 1-13, 2018
252018
TET2-mediated mRNA demethylation regulates leukemia stem cell homing and self-renewal
Y Li, M Xue, X Deng, L Dong, L Ren, L Han, C Li, J Xue, Z Zhao, W Li, ...
Cell Stem Cell 30 (8), 1072-1090. e10, 2023
192023
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