Replication-incompetent adenoviral vaccine vector elicits effective anti-immunodeficiency-virus immunity JW Shiver, TM Fu, L Chen, DR Casimiro, ME Davies, RK Evans, ... Nature 415 (6869), 331-335, 2002 | 1513 | 2002 |
Kinetics of SARS-CoV-2 specific IgM and IgG responses in COVID-19 patients B Sun, Y Feng, X Mo, P Zheng, Q Wang, P Li, P Peng, X Liu, Z Chen, ... Emerging microbes & infections 9 (1), 940-948, 2020 | 534 | 2020 |
Comparative immunogenicity in rhesus monkeys of DNA plasmid, recombinant vaccinia virus, and replication-defective adenovirus vectors expressing a human immunodeficiency virus … DR Casimiro, L Chen, TM Fu, RK Evans, MJ Caulfield, ME Davies, A Tang, ... Journal of virology 77 (11), 6305-6313, 2003 | 507 | 2003 |
Reversal of tolerance to human MUC1 antigen in MUC1 transgenic mice immunized with fusions of dendritic and carcinoma cells J Gong, D Chen, M Kashiwaba, Y Li, L Chen, H Takeuchi, H Qu, ... Proceedings of the National Academy of Sciences 95 (11), 6279-6283, 1998 | 300 | 1998 |
Recombinant modified vaccinia virus Ankara expressing the spike glycoprotein of severe acute respiratory syndrome coronavirus induces protective neutralizing antibodies … Z Chen, L Zhang, C Qin, L Ba, CE Yi, F Zhang, Q Wei, T He, W Yu, J Yu, ... Journal of virology 79 (5), 2678-2688, 2005 | 238 | 2005 |
An adenovirus-vectored COVID-19 vaccine confers protection from SARS-COV-2 challenge in rhesus macaques L Feng, Q Wang, C Shan, C Yang, Y Feng, J Wu, X Liu, Y Zhou, R Jiang, ... Nature communications 11 (1), 4207, 2020 | 226 | 2020 |
Intratumoral activation and enhanced chemotherapeutic effect of oxazaphosphorines following cytochrome P-450 gene transfer: development of a combined chemotherapy/cancer gene … L Chen, DJ Waxman Cancer Research 55 (3), 581-589, 1995 | 209 | 1995 |
An online survey of the attitude and willingness of Chinese adults to receive COVID-19 vaccination M Chen, Y Li, J Chen, Z Wen, F Feng, H Zou, C Fu, L Chen, Y Shu, C Sun Human vaccines & immunotherapeutics 17 (7), 2279-2288, 2021 | 195 | 2021 |
Eradication of murine bladder carcinoma by intratumor injection of a bicistronic adenoviral vector carrying cDNAs for the IL-12 heterodimer and its inhibition by the IL-12 p40 … L Chen, D Chen, E Block, M O'Donnell, DW Kufe, SK Clinton Journal of immunology (Baltimore, Md.: 1950) 159 (1), 351-359, 1997 | 187 | 1997 |
Sensitization of human breast cancer cells to cyclophosphamide and ifosfamide by transfer of a liver cytochrome P450 gene L Chen, DJ Waxman, D Chen, DW Kufe Cancer research 56 (6), 1331-1340, 1996 | 178 | 1996 |
Immunization against murine multiple myeloma with fusions of dendritic and plasmacytoma cells is potentiated by interleukin 12 J Gong, S Koido, D Chen, Y Tanaka, L Huang, D Avigan, K Anderson, ... Blood, The Journal of the American Society of Hematology 99 (7), 2512-2517, 2002 | 163 | 2002 |
Breast cancer selective gene expression and therapy mediated by recombinant adenoviruses containing the DF3/MUC1 promoter. L Chen, D Chen, Y Manome, Y Dong, HA Fine, DW Kufe The Journal of clinical investigation 96 (6), 2775-2782, 1995 | 159 | 1995 |
Induction of antigen-specific antitumor immunity with adenovirus-transduced dendritic cells J Gong, L Chen, D Chen, M Kashiwaba, Y Manome, T Tanaka, D Kufe Gene therapy 4 (10), 1023-1028, 1997 | 148 | 1997 |
MicroRNAs reduce tumor growth and contribute to enhance cytotoxicity induced by gefitinib in non-small cell lung cancer M Zhong, X Ma, C Sun, L Chen Chemico-biological interactions 184 (3), 431-438, 2010 | 147 | 2010 |
Visualizing influenza virus infection in living mice W Pan, Z Dong, F Li, W Meng, L Feng, X Niu, C Li, Q Luo, Z Li, C Sun, ... Nature communications 4 (1), 2369, 2013 | 126 | 2013 |
Vaccine-induced immunity in baboons by using DNA and replication-incompetent adenovirus type 5 vectors expressing a human immunodeficiency virus type 1 gag gene DR Casimiro, A Tang, L Chen, TM Fu, RK Evans, ME Davies, DC Freed, ... Journal of virology 77 (13), 7663-7668, 2003 | 121 | 2003 |
Cytochrome P450 gene-directed enzyme prodrug therapy (GDEPT) for cancer L Chen, DJ Waxman Current pharmaceutical design 8 (15), 1405-1416, 2002 | 117 | 2002 |
Protective humoral and cellular immune responses to SARS-CoV-2 persist up to 1 year after recovery C Feng, J Shi, Q Fan, Y Wang, H Huang, F Chen, G Tang, Y Li, P Li, J Li, ... Nature communications 12 (1), 4984, 2021 | 116 | 2021 |
Potentiation of Cytochrome P450/Cyclophosphamide-based Cancer Gene Therapy by Coexpression of the P450 Reductase Gene L Chen, LJ Yu, DJ Waxm Cancer research 57 (21), 4830-4837, 1997 | 112 | 1997 |
In Vivo Replication-Deficient Adenovirus Vector-Mediated Transduction of the Cytosine Deaminase Gene Sensitizes Glioma Cells to 5-Fluorocytosine Y Dong, P Wen, Y Manome, M Parr, A Hirshowitz, L Chen, EA Hirschowitz, ... Human gene therapy 7 (6), 713-720, 1996 | 99 | 1996 |