Myeloid-derived suppressor cells as a therapeutic target for cancer AMK Law, F Valdes-Mora, D Gallego-Ortega Cells 9 (3), 561, 2020 | 367 | 2020 |
Acetylation of H2A. Z is a key epigenetic modification associated with gene deregulation and epigenetic remodeling in cancer F Valdés-Mora, JZ Song, AL Statham, D Strbenac, MD Robinson, SS Nair, ... Genome research 22 (2), 307-321, 2012 | 225 | 2012 |
Epigenetic reprogramming at estrogen-receptor binding sites alters 3D chromatin landscape in endocrine-resistant breast cancer J Achinger-Kawecka, F Valdes-Mora, PL Luu, KA Giles, CE Caldon, W Qu, ... Nature communications 11 (1), 320, 2020 | 128 | 2020 |
Differential role of human choline kinase α and β enzymes in lipid metabolism: implications in cancer onset and treatment D Gallego-Ortega, A Ramirez de Molina, MA Ramos, F Valdes-Mora, ... PloS one 4 (11), e7819, 2009 | 118 | 2009 |
Cdc42 is highly expressed in colorectal adenocarcinoma and downregulates ID4 through an epigenetic mechanism T Gómez del Pulgar, F Valdés-Mora, E Bandrés, R Pérez-Palacios, ... International journal of oncology 33 (1), 185-193, 2008 | 117 | 2008 |
Droplet-based single cell RNAseq tools: a practical guide R Salomon, D Kaczorowski, F Valdes-Mora, RE Nordon, A Neild, ... Lab on a Chip 19 (10), 1706-1727, 2019 | 104 | 2019 |
ELF5 suppresses estrogen sensitivity and underpins the acquisition of antiestrogen resistance in luminal breast cancer M Kalyuga, D Gallego-Ortega, HJ Lee, DL Roden, MJ Cowley, CE Caldon, ... PLoS biology 10 (12), e1001461, 2012 | 103 | 2012 |
TWIST1 overexpression is associated with nodal invasion and male sex in primary colorectal cancer F Valdés-Mora, T Gomez del Pulgar, E Bandrés, P Cejas, ... Annals of surgical oncology 16, 78-87, 2009 | 103 | 2009 |
Constitutively bound CTCF sites maintain 3D chromatin architecture and long-range epigenetically regulated domains A Khoury, J Achinger-Kawecka, SA Bert, GC Smith, HJ French, PL Luu, ... Nature communications 11 (1), 54, 2020 | 89 | 2020 |
Temporal profiling of the breast tumour microenvironment reveals collagen XII as a driver of metastasis M Papanicolaou, AL Parker, M Yam, EC Filipe, SZ Wu, JL Chitty, K Wyllie, ... Nature communications 13 (1), 4587, 2022 | 87 | 2022 |
Acetylated histone variant H2A. Z is involved in the activation of neo-enhancers in prostate cancer F Valdés-Mora, CM Gould, Y Colino-Sanguino, W Qu, JZ Song, KM Taylor, ... Nature Communications 8 (1), 1346, 2017 | 85 | 2017 |
Single-cell transcriptomics in cancer immunobiology: the future of precision oncology F Valdes-Mora, K Handler, AMK Law, R Salomon, SR Oakes, ... Frontiers in immunology 9, 2582, 2018 | 79 | 2018 |
ELF5 drives lung metastasis in luminal breast cancer through recruitment of Gr1+ CD11b+ myeloid-derived suppressor cells D Gallego-Ortega, A Ledger, DL Roden, AMK Law, A Magenau, ... PLoS biology 13 (12), e1002330, 2015 | 79 | 2015 |
Methyl-CpG-binding protein MBD2 plays a key role in maintenance and spread of DNA methylation at CpG islands and shores in cancer C Stirzaker, JZ Song, W Ng, Q Du, NJ Armstrong, WJ Locke, AL Statham, ... Oncogene 36 (10), 1328-1338, 2017 | 77 | 2017 |
Tamoxifen-induced epigenetic silencing of oestrogen-regulated genes in anti-hormone resistant breast cancer A Stone, F Valdes-Mora, JMW Gee, L Farrow, RA McClelland, H Fiegl, ... Plos one 7 (7), e40466, 2012 | 75 | 2012 |
Involvement of human choline kinase alpha and beta in carcinogenesis: a different role in lipid metabolism and biological functions D Gallego-Ortega, TG del Pulgar, F Valdés-Mora, A Cebrián, JC Lacal Advances in enzyme regulation 51 (1), 183-194, 2011 | 64 | 2011 |
Prostate cancer epigenetic biomarkers: next-generation technologies F Valdes-Mora, SJ Clark Oncogene 34 (13), 1609-1618, 2015 | 61 | 2015 |
BCL-2 hypermethylation is a potential biomarker of sensitivity to antimitotic chemotherapy in endocrine-resistant breast cancer A Stone, MJ Cowley, F Valdes-Mora, RA McCloy, CM Sergio, ... Molecular cancer therapeutics 12 (9), 1874-1885, 2013 | 61* | 2013 |
Single-cell transcriptomics reveals involution mimicry during the specification of the basal breast cancer subtype F Valdes-Mora, R Salomon, BS Gloss, AMK Law, J Venhuizen, L Castillo, ... Cell Reports 35 (2), 2021 | 59* | 2021 |
Lineage Specific Methylation of the Elf5 Promoter in Mammary Epithelial Cells HJ Lee, RA Hinshelwood, T Bouras, D Gallego-Ortega, F Valdés-Mora, ... Stem cells 29 (10), 1611-1619, 2011 | 58 | 2011 |