The evolving modern management of brain metastasis PE Fecci, CD Champion, J Hoj, CM McKernan, CR Goodwin, ... Clinical Cancer Research 25 (22), 6570-6580, 2019 | 125 | 2019 |
A TAZ-AXL-ABL2 feed-forward signaling axis promotes lung adenocarcinoma brain metastasis JP Hoj, B Mayro, AM Pendergast Cell reports 29 (11), 3421-3434. e8, 2019 | 53 | 2019 |
The ABL2 kinase regulates an HSF1-dependent transcriptional program required for lung adenocarcinoma brain metastasis JP Hoj, B Mayro, AM Pendergast Proceedings of the National Academy of Sciences 117 (52), 33486-33495, 2020 | 28 | 2020 |
Mesenchymal stem cells promote metastasis through activation of an ABL-MMP9 signaling axis in lung cancer cells JJ Gu, J Hoj, C Rouse, AM Pendergast PLoS One 15 (10), e0241423, 2020 | 28 | 2020 |
P2RY2-AKT activation is a therapeutically actionable consequence of XPO1 inhibition in acute myeloid leukemia KH Lin, JC Rutter, A Xie, ST Killarney, C Vaganay, C Benaksas, F Ling, ... Nature cancer 3 (7), 837-851, 2022 | 23 | 2022 |
Pharmacology and in vivo efficacy of pyridine-pyrimidine amides that inhibit microtubule polymerization A Siddiqui-Jain, JP Hoj, DW Cescon, MD Hansen Bioorganic & medicinal chemistry letters 28 (5), 934-941, 2018 | 17 | 2018 |
Cellular contractility changes are sufficient to drive epithelial scattering JP Hoj, JA Davis, KE Fullmer, DJ Morrell, NE Saguibo, JT Schuler, ... Experimental cell research 326 (2), 187-200, 2014 | 16 | 2014 |
Executioner caspases restrict mitochondrial RNA-driven Type I IFN induction during chemotherapy-induced apoptosis ST Killarney, R Washart, RS Soderquist, JP Hoj, J Lebhar, KH Lin, ... Nature Communications 14 (1), 1399, 2023 | 14 | 2023 |
ABL allosteric inhibitors synergize with statins to enhance apoptosis of metastatic lung cancer cells JH Luttman, JP Hoj, KH Lin, J Lin, JJ Gu, C Rouse, AG Nichols, ... Cell reports 37 (4), 2021 | 9 | 2021 |
CBF-Beta Mitigates PI3K-Alpha–Specific Inhibitor Killing through PIM1 in PIK3CA-Mutant Gastric Cancer LJ Stanland, HX Ang, JP Hoj, Y Chu, P Tan, KC Wood, MA Luftig Molecular Cancer Research 21 (11), 1148-1162, 2023 | 6 | 2023 |
Pyridine-pyrimidine amides that prevent HGF-induced epithelial scattering by two distinct mechanisms A Siddiqui-Jain, JP Hoj, JB Hargiss, TH Hoj, CJ Payne, CA Ritchie, ... Bioorganic & Medicinal Chemistry Letters 27 (17), 3992-4000, 2017 | 6 | 2017 |
ABL1 and ABL2 promote medulloblastoma leptomeningeal dissemination JK Jones, H Zhang, AM Lyne, FMG Cavalli, WE Hassen, K Stevenson, ... Neuro-Oncology Advances 5 (1), vdad095, 2023 | 5 | 2023 |
ABL kinases regulate the stabilization of HIF-1α and MYC through CPSF1 B Mayro, JP Hoj, CG Cerda-Smith, HM Hutchinson, MW Caminear, ... Proceedings of the National Academy of Sciences 120 (16), e2210418120, 2023 | 4 | 2023 |
The Characterization of Tyrosine Kinase-Dependent Signaling Networks Required for Lung Cancer Brain Metastasis JP Hoj Duke University, 2020 | 1 | 2020 |
Activation of KrasG12D in Subset of Alveolar Type II Cells Enhances Cellular Plasticity in Lung Adenocarcinoma P Chaudhary, X Xu, G Wang, JP Hoj, RR Rampersad, ML Asselin-Labat, ... Cancer Research Communications 3 (11), 2400-2411, 2023 | | 2023 |
Identification of novel regulators of response to PI3Ka inhibition in PIK3CA mutant gastric cancer L Stanland, H Ang, J Hoj, Y Chu, P Tan, K Wood, M Luftig Cancer Research 83 (7_Supplement), 4949-4949, 2023 | | 2023 |
MCB-613 exploits a collateral sensitivity in drug resistant EGFR-mutant non-small cell lung cancer through covalent inhibition of KEAP1 CF Bassil, GR Anderson, B Mayro, KN Askin, PS Winter, S Gruber, ... bioRxiv, 2023 | | 2023 |
BSCI-05. ABL2-HSF1-E2F signaling axis promotes lung adenocarcinoma brain metastasis AM Pendergast, J Hoj, B Mayro Neuro-oncology Advances 3 (Suppl 3), iii2, 2021 | | 2021 |
An actionable AXL-ABL2-TAZ signaling axis promotes lung adenocarcinoma metastasis to the brain. JP Hoj, BJ Mayro, AM Pendergast MOLECULAR CANCER RESEARCH 18 (8), 53-53, 2020 | | 2020 |
Abstract B25: An actionable AXL-ABL2-TAZ signaling axis promotes lung adenocarcinoma metastasis to the brain JP Hoj, BJ Mayro, AM Pendergast Molecular Cancer Research 18 (8_Supplement), B25-B25, 2020 | | 2020 |