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Jacob Hoj
Jacob Hoj
Tavros Therapeutics
在 tavrostx.com 的电子邮件经过验证
标题
引用次数
引用次数
年份
The evolving modern management of brain metastasis
PE Fecci, CD Champion, J Hoj, CM McKernan, CR Goodwin, ...
Clinical Cancer Research 25 (22), 6570-6580, 2019
1252019
A TAZ-AXL-ABL2 feed-forward signaling axis promotes lung adenocarcinoma brain metastasis
JP Hoj, B Mayro, AM Pendergast
Cell reports 29 (11), 3421-3434. e8, 2019
532019
The ABL2 kinase regulates an HSF1-dependent transcriptional program required for lung adenocarcinoma brain metastasis
JP Hoj, B Mayro, AM Pendergast
Proceedings of the National Academy of Sciences 117 (52), 33486-33495, 2020
282020
Mesenchymal stem cells promote metastasis through activation of an ABL-MMP9 signaling axis in lung cancer cells
JJ Gu, J Hoj, C Rouse, AM Pendergast
PLoS One 15 (10), e0241423, 2020
282020
P2RY2-AKT activation is a therapeutically actionable consequence of XPO1 inhibition in acute myeloid leukemia
KH Lin, JC Rutter, A Xie, ST Killarney, C Vaganay, C Benaksas, F Ling, ...
Nature cancer 3 (7), 837-851, 2022
232022
Pharmacology and in vivo efficacy of pyridine-pyrimidine amides that inhibit microtubule polymerization
A Siddiqui-Jain, JP Hoj, DW Cescon, MD Hansen
Bioorganic & medicinal chemistry letters 28 (5), 934-941, 2018
172018
Cellular contractility changes are sufficient to drive epithelial scattering
JP Hoj, JA Davis, KE Fullmer, DJ Morrell, NE Saguibo, JT Schuler, ...
Experimental cell research 326 (2), 187-200, 2014
162014
Executioner caspases restrict mitochondrial RNA-driven Type I IFN induction during chemotherapy-induced apoptosis
ST Killarney, R Washart, RS Soderquist, JP Hoj, J Lebhar, KH Lin, ...
Nature Communications 14 (1), 1399, 2023
142023
ABL allosteric inhibitors synergize with statins to enhance apoptosis of metastatic lung cancer cells
JH Luttman, JP Hoj, KH Lin, J Lin, JJ Gu, C Rouse, AG Nichols, ...
Cell reports 37 (4), 2021
92021
CBF-Beta Mitigates PI3K-Alpha–Specific Inhibitor Killing through PIM1 in PIK3CA-Mutant Gastric Cancer
LJ Stanland, HX Ang, JP Hoj, Y Chu, P Tan, KC Wood, MA Luftig
Molecular Cancer Research 21 (11), 1148-1162, 2023
62023
Pyridine-pyrimidine amides that prevent HGF-induced epithelial scattering by two distinct mechanisms
A Siddiqui-Jain, JP Hoj, JB Hargiss, TH Hoj, CJ Payne, CA Ritchie, ...
Bioorganic & Medicinal Chemistry Letters 27 (17), 3992-4000, 2017
62017
ABL1 and ABL2 promote medulloblastoma leptomeningeal dissemination
JK Jones, H Zhang, AM Lyne, FMG Cavalli, WE Hassen, K Stevenson, ...
Neuro-Oncology Advances 5 (1), vdad095, 2023
52023
ABL kinases regulate the stabilization of HIF-1α and MYC through CPSF1
B Mayro, JP Hoj, CG Cerda-Smith, HM Hutchinson, MW Caminear, ...
Proceedings of the National Academy of Sciences 120 (16), e2210418120, 2023
42023
The Characterization of Tyrosine Kinase-Dependent Signaling Networks Required for Lung Cancer Brain Metastasis
JP Hoj
Duke University, 2020
12020
Activation of KrasG12D in Subset of Alveolar Type II Cells Enhances Cellular Plasticity in Lung Adenocarcinoma
P Chaudhary, X Xu, G Wang, JP Hoj, RR Rampersad, ML Asselin-Labat, ...
Cancer Research Communications 3 (11), 2400-2411, 2023
2023
Identification of novel regulators of response to PI3Ka inhibition in PIK3CA mutant gastric cancer
L Stanland, H Ang, J Hoj, Y Chu, P Tan, K Wood, M Luftig
Cancer Research 83 (7_Supplement), 4949-4949, 2023
2023
MCB-613 exploits a collateral sensitivity in drug resistant EGFR-mutant non-small cell lung cancer through covalent inhibition of KEAP1
CF Bassil, GR Anderson, B Mayro, KN Askin, PS Winter, S Gruber, ...
bioRxiv, 2023
2023
BSCI-05. ABL2-HSF1-E2F signaling axis promotes lung adenocarcinoma brain metastasis
AM Pendergast, J Hoj, B Mayro
Neuro-oncology Advances 3 (Suppl 3), iii2, 2021
2021
An actionable AXL-ABL2-TAZ signaling axis promotes lung adenocarcinoma metastasis to the brain.
JP Hoj, BJ Mayro, AM Pendergast
MOLECULAR CANCER RESEARCH 18 (8), 53-53, 2020
2020
Abstract B25: An actionable AXL-ABL2-TAZ signaling axis promotes lung adenocarcinoma metastasis to the brain
JP Hoj, BJ Mayro, AM Pendergast
Molecular Cancer Research 18 (8_Supplement), B25-B25, 2020
2020
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