关注
Pek Lum
Pek Lum
未知所在单位机构
在 auransa.com 的电子邮件经过验证
标题
引用次数
引用次数
年份
Functional discovery via a compendium of expression profiles
TR Hughes, MJ Marton, AR Jones, CJ Roberts, R Stoughton, CD Armour, ...
Cell 102 (1), 109-126, 2000
33122000
An integrative genomics approach to infer causal associations between gene expression and disease
EE Schadt, J Lamb, X Yang, J Zhu, S Edwards, D GuhaThakurta, ...
Nature genetics 37 (7), 710-717, 2005
12342005
Mapping the genetic architecture of gene expression in human liver
EE Schadt, C Molony, E Chudin, K Hao, X Yang, PY Lum, A Kasarskis, ...
PLoS biology 6 (5), e107, 2008
11932008
Variations in DNA elucidate molecular networks that cause disease
Y Chen, J Zhu, PY Lum, X Yang, S Pinto, DJ MacNeil, C Zhang, J Lamb, ...
Nature 452 (7186), 429-435, 2008
10692008
Extracting insights from the shape of complex data using topology
PY Lum, G Singh, A Lehman, T Ishkanov, M Vejdemo-Johansson, ...
Scientific reports 3 (1), 1236, 2013
6302013
Experimental annotation of the human genome using microarray technology
DD Shoemaker, EE Schadt, CD Armour, YD He, P Garrett-Engele, ...
Nature 409 (6822), 922-927, 2001
6252001
Discovering modes of action for therapeutic compounds using a genome-wide screen of yeast heterozygotes
PY Lum, CD Armour, SB Stepaniants, G Cavet, MK Wolf, JS Butler, ...
Cell 116 (1), 121-137, 2004
5802004
Clustering of hepatotoxins based on mechanism of toxicity using gene expression profiles
JF Waring, RA Jolly, R Ciurlionis, PY Lum, JT Praestgaard, DC Morfitt, ...
Toxicology and applied pharmacology 175 (1), 28-42, 2001
4772001
Validation of candidate causal genes for obesity that affect shared metabolic pathways and networks
X Yang, JL Deignan, H Qi, J Zhu, S Qian, J Zhong, G Torosyan, S Majid, ...
Nature genetics 41 (4), 415-423, 2009
3272009
Systematic genetic and genomic analysis of cytochrome P450 enzyme activities in human liver
X Yang, B Zhang, C Molony, E Chudin, K Hao, J Zhu, A Gaedigk, C Suver, ...
Genome research 20 (8), 1020-1036, 2010
3192010
An integrative genomics approach to the reconstruction of gene networks in segregating populations
J Zhu, PY Lum, J Lamb, D GuhaThakurta, SW Edwards, R Thieringer, ...
Cytogenetic and genome research 105 (2-4), 363-374, 2004
2892004
Increasing the power to detect causal associations by combining genotypic and expression data in segregating populations
J Zhu, MC Wiener, C Zhang, A Fridman, E Minch, PY Lum, JR Sachs, ...
PLoS computational biology 3 (4), e69, 2007
2612007
Integrating genotypic and expression data in a segregating mouse population to identify 5-lipoxygenase as a susceptibility gene for obesity and bone traits
M Mehrabian, H Allayee, J Stockton, PY Lum, TA Drake, LW Castellani, ...
Nature genetics 37 (11), 1224-1233, 2005
2452005
DiOC6 staining reveals organelle structure and dynamics in living yeast cells
AJ Koning, PY Lum, JM Williams, R Wright
Cell motility and the cytoskeleton 25 (2), 111-128, 1993
2341993
Topological data analysis for discovery in preclinical spinal cord injury and traumatic brain injury
JL Nielson, J Paquette, AW Liu, CF Guandique, CA Tovar, T Inoue, ...
Nature communications 6 (1), 8581, 2015
2252015
Innate and adaptive T cells in asthmatic patients: relationship to severity and disease mechanisms
TSC Hinks, X Zhou, KJ Staples, BD Dimitrov, A Manta, T Petrossian, ...
Journal of allergy and clinical immunology 136 (2), 323-333, 2015
2182015
A survey of the genetics of stomach, liver, and adipose gene expression from a morbidly obese cohort
DM Greenawalt, R Dobrin, E Chudin, IJ Hatoum, C Suver, J Beaulaurier, ...
Genome research 21 (7), 1008-1016, 2011
2132011
Liver and adipose expression associated SNPs are enriched for association to type 2 diabetes
H Zhong, J Beaulaurier, PY Lum, C Molony, X Yang, DJ MacNeil, ...
PLoS genetics 6 (5), e1000932, 2010
2072010
Obesity and genetics regulate microRNAs in islets, liver, and adipose of diabetic mice
E Zhao, MP Keller, ME Rabaglia, AT Oler, DS Stapleton, KL Schueler, ...
Mammalian Genome 20, 476-485, 2009
1682009
Integrating QTL and high-density SNP analyses in mice to identify Insig2 as a susceptibility gene for plasma cholesterol levels
AC Cervino, G Li, S Edwards, J Zhu, C Laurie, G Tokiwa, PY Lum, S Wang, ...
Genomics 86 (5), 505-517, 2005
1602005
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