Functional discovery via a compendium of expression profiles TR Hughes, MJ Marton, AR Jones, CJ Roberts, R Stoughton, CD Armour, ... Cell 102 (1), 109-126, 2000 | 3312 | 2000 |
An integrative genomics approach to infer causal associations between gene expression and disease EE Schadt, J Lamb, X Yang, J Zhu, S Edwards, D GuhaThakurta, ... Nature genetics 37 (7), 710-717, 2005 | 1234 | 2005 |
Mapping the genetic architecture of gene expression in human liver EE Schadt, C Molony, E Chudin, K Hao, X Yang, PY Lum, A Kasarskis, ... PLoS biology 6 (5), e107, 2008 | 1193 | 2008 |
Variations in DNA elucidate molecular networks that cause disease Y Chen, J Zhu, PY Lum, X Yang, S Pinto, DJ MacNeil, C Zhang, J Lamb, ... Nature 452 (7186), 429-435, 2008 | 1069 | 2008 |
Extracting insights from the shape of complex data using topology PY Lum, G Singh, A Lehman, T Ishkanov, M Vejdemo-Johansson, ... Scientific reports 3 (1), 1236, 2013 | 630 | 2013 |
Experimental annotation of the human genome using microarray technology DD Shoemaker, EE Schadt, CD Armour, YD He, P Garrett-Engele, ... Nature 409 (6822), 922-927, 2001 | 625 | 2001 |
Discovering modes of action for therapeutic compounds using a genome-wide screen of yeast heterozygotes PY Lum, CD Armour, SB Stepaniants, G Cavet, MK Wolf, JS Butler, ... Cell 116 (1), 121-137, 2004 | 580 | 2004 |
Clustering of hepatotoxins based on mechanism of toxicity using gene expression profiles JF Waring, RA Jolly, R Ciurlionis, PY Lum, JT Praestgaard, DC Morfitt, ... Toxicology and applied pharmacology 175 (1), 28-42, 2001 | 477 | 2001 |
Validation of candidate causal genes for obesity that affect shared metabolic pathways and networks X Yang, JL Deignan, H Qi, J Zhu, S Qian, J Zhong, G Torosyan, S Majid, ... Nature genetics 41 (4), 415-423, 2009 | 327 | 2009 |
Systematic genetic and genomic analysis of cytochrome P450 enzyme activities in human liver X Yang, B Zhang, C Molony, E Chudin, K Hao, J Zhu, A Gaedigk, C Suver, ... Genome research 20 (8), 1020-1036, 2010 | 319 | 2010 |
An integrative genomics approach to the reconstruction of gene networks in segregating populations J Zhu, PY Lum, J Lamb, D GuhaThakurta, SW Edwards, R Thieringer, ... Cytogenetic and genome research 105 (2-4), 363-374, 2004 | 289 | 2004 |
Increasing the power to detect causal associations by combining genotypic and expression data in segregating populations J Zhu, MC Wiener, C Zhang, A Fridman, E Minch, PY Lum, JR Sachs, ... PLoS computational biology 3 (4), e69, 2007 | 261 | 2007 |
Integrating genotypic and expression data in a segregating mouse population to identify 5-lipoxygenase as a susceptibility gene for obesity and bone traits M Mehrabian, H Allayee, J Stockton, PY Lum, TA Drake, LW Castellani, ... Nature genetics 37 (11), 1224-1233, 2005 | 245 | 2005 |
DiOC6 staining reveals organelle structure and dynamics in living yeast cells AJ Koning, PY Lum, JM Williams, R Wright Cell motility and the cytoskeleton 25 (2), 111-128, 1993 | 234 | 1993 |
Topological data analysis for discovery in preclinical spinal cord injury and traumatic brain injury JL Nielson, J Paquette, AW Liu, CF Guandique, CA Tovar, T Inoue, ... Nature communications 6 (1), 8581, 2015 | 225 | 2015 |
Innate and adaptive T cells in asthmatic patients: relationship to severity and disease mechanisms TSC Hinks, X Zhou, KJ Staples, BD Dimitrov, A Manta, T Petrossian, ... Journal of allergy and clinical immunology 136 (2), 323-333, 2015 | 218 | 2015 |
A survey of the genetics of stomach, liver, and adipose gene expression from a morbidly obese cohort DM Greenawalt, R Dobrin, E Chudin, IJ Hatoum, C Suver, J Beaulaurier, ... Genome research 21 (7), 1008-1016, 2011 | 213 | 2011 |
Liver and adipose expression associated SNPs are enriched for association to type 2 diabetes H Zhong, J Beaulaurier, PY Lum, C Molony, X Yang, DJ MacNeil, ... PLoS genetics 6 (5), e1000932, 2010 | 207 | 2010 |
Obesity and genetics regulate microRNAs in islets, liver, and adipose of diabetic mice E Zhao, MP Keller, ME Rabaglia, AT Oler, DS Stapleton, KL Schueler, ... Mammalian Genome 20, 476-485, 2009 | 168 | 2009 |
Integrating QTL and high-density SNP analyses in mice to identify Insig2 as a susceptibility gene for plasma cholesterol levels AC Cervino, G Li, S Edwards, J Zhu, C Laurie, G Tokiwa, PY Lum, S Wang, ... Genomics 86 (5), 505-517, 2005 | 160 | 2005 |