Oxidative stress in the tumor microenvironment and its relevance to cancer immunotherapy NS Aboelella, C Brandle, T Kim, ZC Ding, G Zhou Cancers 13 (5), 986, 2021 | 122 | 2021 |
Persistent STAT5 activation reprograms the epigenetic landscape in CD4+ T cells to drive polyfunctionality and antitumor immunity ZC Ding, H Shi, NS Aboelella, K Fesenkova, EJ Park, Z Liu, L Pei, J Li, ... Science immunology 5 (52), eaba5962, 2020 | 58 | 2020 |
PDE5 and PDE10 inhibition activates cGMP/PKG signaling to block Wnt/β-catenin transcription, cancer cell growth, and tumor immunity GA Piazza, A Ward, X Chen, Y Maxuitenko, A Coley, NS Aboelella, ... Drug discovery today 25 (8), 1521-1527, 2020 | 56 | 2020 |
The monocytes that repopulate in mice after cyclophosphamide treatment acquire a neutrophil precursor gene signature and immunosuppressive activity ZC Ding, NS Aboelella, L Bryan, H Shi, G Zhou Frontiers in immunology 11, 594540, 2021 | 9 | 2021 |
Indomethacin-induced oxidative stress enhances death receptor 5 signaling and sensitizes tumor cells to adoptive T-cell therapy NS Aboelella, C Brandle, O Okoko, MY Gazi, ZC Ding, H Xu, G Gorman, ... Journal for Immunotherapy of Cancer 10 (7), 2022 | 5 | 2022 |
Venetoclax Induces BCL-2–Dependent Treg to TH17 Plasticity to Enhance the Antitumor Efficacy of Anti–PD-1 Checkpoint Blockade R Liao, JY Hsu, NS Aboelella, JA McKeever, AT Thomas-Toth, AS Koh, ... Cancer Immunology Research, OF1-OF16, 2024 | | 2024 |
869 Venetoclax, a specific BCL-2 inhibitor, modulates CAR T cells genetically and functionally during production and augments their anti-tumor response NS Aboelella, R Park, T Pan, E Tang, J Huang, J LaBelle Journal for ImmunoTherapy of Cancer 11 (Suppl 1), 2023 | | 2023 |
795 STAT3 signaling as a checkpoint for TLR9-driven epigenetic reprogramming of acute myeloid leukemia into antigen-presenting cells D Wang, P Duttagupta, YL Su, H Li, M Feng, B Zhang, YH Kuo, ... Journal for ImmunoTherapy of Cancer 10 (Suppl 2), 2022 | | 2022 |
NSAIDs-induced oxidative stress sensitizes tumor cells to T cell cytotoxicity through the TRAIL-DR5 axis NS Aboelella, G Zhou The Journal of Immunology 208 (1_Supplement), 117.01-117.01, 2022 | | 2022 |
Indomethacin-Induced Oxidative Stress Sensitizes Tumor Cells to T Cell Cytotoxicity Through the Trail-DR5 Axis NS Aboelella Augusta University, 2021 | | 2021 |
Adding fuel to the fire: Augmenting the efficacy of adoptive T-cell therapy with pro-oxidants N Aboelella, G Zhou, K Fesenkova, Z Ding Cancer Research 79 (13_Supplement), 4095-4095, 2019 | | 2019 |