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Dirk A Lamprecht
Dirk A Lamprecht
Johnson & Johnson Innovative Medicines
在 its.jnj.com 的电子邮件经过验证
标题
引用次数
引用次数
年份
Turning the respiratory flexibility of Mycobacterium tuberculosis against itself
DA Lamprecht, PM Finin, MA Rahman, BM Cumming, SL Russell, ...
Nature communications 7 (1), 12393, 2016
2112016
Ergothioneine maintains redox and bioenergetic homeostasis essential for drug susceptibility and virulence of Mycobacterium tuberculosis
V Saini, BM Cumming, L Guidry, DA Lamprecht, JH Adamson, VP Reddy, ...
Cell reports 14 (3), 572-585, 2016
1482016
Hydrogen sulfide stimulates Mycobacterium tuberculosis respiration, growth and pathogenesis
V Saini, KC Chinta, VP Reddy, JN Glasgow, A Stein, DA Lamprecht, ...
Nature communications 11 (1), 557, 2020
872020
Compromised metabolic reprogramming is an early indicator of CD8+ T cell dysfunction during chronic Mycobacterium tuberculosis infection
SL Russell, DA Lamprecht, T Mandizvo, TT Jones, V Naidoo, KW Addicott, ...
Cell reports 29 (11), 3564-3579. e5, 2019
712019
Susceptibility of Mycobacterium tuberculosis Cytochrome bd Oxidase Mutants to Compounds Targeting the Terminal Respiratory Oxidase, Cytochrome c
A Moosa, DA Lamprecht, K Arora, CE Barry III, HIM Boshoff, TR Ioerger, ...
Antimicrobial agents and chemotherapy 61 (10), 10.1128/aac. 01338-17, 2017
632017
Arylvinylpiperazine amides, a new class of potent inhibitors targeting QcrB of Mycobacterium tuberculosis
CS Foo, A Lupien, M Kienle, A Vocat, A Benjak, R Sommer, ...
MBio 9 (5), 10.1128/mbio. 01276-18, 2018
622018
2-Mercapto-Quinazolinones as Inhibitors of Type II NADH Dehydrogenase and Mycobacterium tuberculosis: Structure–Activity Relationships, Mechanism of Action …
D Murugesan, PC Ray, T Bayliss, GA Prosser, JR Harrison, K Green, ...
ACS infectious diseases 4 (6), 954-969, 2018
592018
The physiology and genetics of oxidative stress in mycobacteria
BM Cumming, DA Lamprecht, RM Wells, V Saini, JH Mazorodze, ...
Molecular Genetics of Mycobacteria, 297-322, 2014
462014
Mycobacterium tuberculosis arrests host cycle at the G1/S transition to establish long term infection
BM Cumming, MA Rahman, DA Lamprecht, KH Rohde, V Saini, ...
PLoS pathogens 13 (5), e1006389, 2017
452017
New 2-Ethylthio-4-methylaminoquinazoline derivatives inhibiting two subunits of cytochrome bc1 in Mycobacterium tuberculosis
A Lupien, CSY Foo, S Savina, A Vocat, J Piton, N Monakhova, A Benjak, ...
PLoS pathogens 16 (1), e1008270, 2020
422020
Turning the respiratory flexibility of Mycobacterium tuberculosis against itself. Nat Commun 7: 12393
DA Lamprecht, PM Finin, MA Rahman, BM Cumming, SL Russell, ...
382016
Bedaquiline reprograms central metabolism to reveal glycolytic vulnerability in Mycobacterium tuberculosis
JS Mackenzie, DA Lamprecht, R Asmal, JH Adamson, K Borah, ...
Nature communications 11 (1), 6092, 2020
362020
Accessible and distinct decoquinate derivatives active against Mycobacterium tuberculosis and apicomplexan parasites
RM Beteck, R Seldon, D Coertzen, ME van der Watt, J Reader, ...
Communications Chemistry 1 (1), 62, 2018
342018
Mycobacterium tuberculosis H2S Functions as a Sink to Modulate Central Metabolism, Bioenergetics, and Drug Susceptibility
TTR Kunota, MA Rahman, BE Truebody, JS Mackenzie, V Saini, ...
Antioxidants 10 (8), 1285, 2021
122021
An enzyme-initiated Smiles rearrangement enables the development of an assay of MshB, the GlcNAc-Ins deacetylase of mycothiol biosynthesis
DA Lamprecht, NO Muneri, H Eastwood, KJ Naidoo, E Strauss, A Jardine
Organic & Biomolecular Chemistry 10 (27), 5278-5288, 2012
112012
The physiology and genetics of oxidative stress in mycobac teria. Microbiol Spectr 2
BM Cumming, DA Lamprecht, RM Wells, V Saini, JH Mazorodze, ...
MGM2-0019-2013, 2014
72014
667 Adamson JH, Steyn AJ. 2016
DA Lamprecht, PM Finin, MA Rahman, BM Cumming, SL Russell, ...
Turning the respiratory flexibility of Mycobacterium 668, 0
4
Correction: Mycobacterium tuberculosis arrests host cycle at the G1/S transition to establish long term infection
BM Cumming, MA Rahman, DA Lamprecht, KH Rohde, V Saini, ...
Plos Pathogens 13 (7), e1006490, 2017
32017
A high-throughput target-based screening approach for the identification and assessment of Mycobacterium tuberculosis mycothione reductase inhibitors
N Smiejkowska, L Oorts, K Van Calster, L De Vooght, R Geens, ...
Microbiology Spectrum 12 (3), e03723-23, 2024
22024
2-Mercapto-quinazolinones as inhibitors of NDH-2 and Mycobacterium tuberculosis: Structure-activity relationships, mechanism of action and ADME characterization.
D Murugesan, PC Ray, T Bayliss, GA Prosser, JR Harrison, K Green, ...
ACS Infect. Dis. 4, 954-969, 2018
12018
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