Turning the respiratory flexibility of Mycobacterium tuberculosis against itself DA Lamprecht, PM Finin, MA Rahman, BM Cumming, SL Russell, ... Nature communications 7 (1), 12393, 2016 | 211 | 2016 |
Ergothioneine maintains redox and bioenergetic homeostasis essential for drug susceptibility and virulence of Mycobacterium tuberculosis V Saini, BM Cumming, L Guidry, DA Lamprecht, JH Adamson, VP Reddy, ... Cell reports 14 (3), 572-585, 2016 | 148 | 2016 |
Hydrogen sulfide stimulates Mycobacterium tuberculosis respiration, growth and pathogenesis V Saini, KC Chinta, VP Reddy, JN Glasgow, A Stein, DA Lamprecht, ... Nature communications 11 (1), 557, 2020 | 87 | 2020 |
Compromised metabolic reprogramming is an early indicator of CD8+ T cell dysfunction during chronic Mycobacterium tuberculosis infection SL Russell, DA Lamprecht, T Mandizvo, TT Jones, V Naidoo, KW Addicott, ... Cell reports 29 (11), 3564-3579. e5, 2019 | 71 | 2019 |
Susceptibility of Mycobacterium tuberculosis Cytochrome bd Oxidase Mutants to Compounds Targeting the Terminal Respiratory Oxidase, Cytochrome c A Moosa, DA Lamprecht, K Arora, CE Barry III, HIM Boshoff, TR Ioerger, ... Antimicrobial agents and chemotherapy 61 (10), 10.1128/aac. 01338-17, 2017 | 63 | 2017 |
Arylvinylpiperazine amides, a new class of potent inhibitors targeting QcrB of Mycobacterium tuberculosis CS Foo, A Lupien, M Kienle, A Vocat, A Benjak, R Sommer, ... MBio 9 (5), 10.1128/mbio. 01276-18, 2018 | 62 | 2018 |
2-Mercapto-Quinazolinones as Inhibitors of Type II NADH Dehydrogenase and Mycobacterium tuberculosis: Structure–Activity Relationships, Mechanism of Action … D Murugesan, PC Ray, T Bayliss, GA Prosser, JR Harrison, K Green, ... ACS infectious diseases 4 (6), 954-969, 2018 | 59 | 2018 |
The physiology and genetics of oxidative stress in mycobacteria BM Cumming, DA Lamprecht, RM Wells, V Saini, JH Mazorodze, ... Molecular Genetics of Mycobacteria, 297-322, 2014 | 46 | 2014 |
Mycobacterium tuberculosis arrests host cycle at the G1/S transition to establish long term infection BM Cumming, MA Rahman, DA Lamprecht, KH Rohde, V Saini, ... PLoS pathogens 13 (5), e1006389, 2017 | 45 | 2017 |
New 2-Ethylthio-4-methylaminoquinazoline derivatives inhibiting two subunits of cytochrome bc1 in Mycobacterium tuberculosis A Lupien, CSY Foo, S Savina, A Vocat, J Piton, N Monakhova, A Benjak, ... PLoS pathogens 16 (1), e1008270, 2020 | 42 | 2020 |
Turning the respiratory flexibility of Mycobacterium tuberculosis against itself. Nat Commun 7: 12393 DA Lamprecht, PM Finin, MA Rahman, BM Cumming, SL Russell, ... | 38 | 2016 |
Bedaquiline reprograms central metabolism to reveal glycolytic vulnerability in Mycobacterium tuberculosis JS Mackenzie, DA Lamprecht, R Asmal, JH Adamson, K Borah, ... Nature communications 11 (1), 6092, 2020 | 36 | 2020 |
Accessible and distinct decoquinate derivatives active against Mycobacterium tuberculosis and apicomplexan parasites RM Beteck, R Seldon, D Coertzen, ME van der Watt, J Reader, ... Communications Chemistry 1 (1), 62, 2018 | 34 | 2018 |
Mycobacterium tuberculosis H2S Functions as a Sink to Modulate Central Metabolism, Bioenergetics, and Drug Susceptibility TTR Kunota, MA Rahman, BE Truebody, JS Mackenzie, V Saini, ... Antioxidants 10 (8), 1285, 2021 | 12 | 2021 |
An enzyme-initiated Smiles rearrangement enables the development of an assay of MshB, the GlcNAc-Ins deacetylase of mycothiol biosynthesis DA Lamprecht, NO Muneri, H Eastwood, KJ Naidoo, E Strauss, A Jardine Organic & Biomolecular Chemistry 10 (27), 5278-5288, 2012 | 11 | 2012 |
The physiology and genetics of oxidative stress in mycobac teria. Microbiol Spectr 2 BM Cumming, DA Lamprecht, RM Wells, V Saini, JH Mazorodze, ... MGM2-0019-2013, 2014 | 7 | 2014 |
667 Adamson JH, Steyn AJ. 2016 DA Lamprecht, PM Finin, MA Rahman, BM Cumming, SL Russell, ... Turning the respiratory flexibility of Mycobacterium 668, 0 | 4 | |
Correction: Mycobacterium tuberculosis arrests host cycle at the G1/S transition to establish long term infection BM Cumming, MA Rahman, DA Lamprecht, KH Rohde, V Saini, ... Plos Pathogens 13 (7), e1006490, 2017 | 3 | 2017 |
A high-throughput target-based screening approach for the identification and assessment of Mycobacterium tuberculosis mycothione reductase inhibitors N Smiejkowska, L Oorts, K Van Calster, L De Vooght, R Geens, ... Microbiology Spectrum 12 (3), e03723-23, 2024 | 2 | 2024 |
2-Mercapto-quinazolinones as inhibitors of NDH-2 and Mycobacterium tuberculosis: Structure-activity relationships, mechanism of action and ADME characterization. D Murugesan, PC Ray, T Bayliss, GA Prosser, JR Harrison, K Green, ... ACS Infect. Dis. 4, 954-969, 2018 | 1 | 2018 |