| Intrathecal delivery of frataxin mRNA encapsulated in lipid nanoparticles to dorsal root ganglia as a potential therapeutic for Friedreich's ataxia J Nabhan, K Wood, V Rao, J Morin, S Bhamidipaty, T LaBranche, ... Scientific Reports, 2016 | 136 | 2016 |
| In vivo overexpression of frataxin causes toxicity mediated by iron-sulfur cluster deficiency C Huichalaf, TL Perfitt, A Kuperman, R Gooch, RC Kovi, KA Brenneman, ... Molecular Therapy-Methods & Clinical Development 24, 367-378, 2022 | 33 | 2022 |
| 4′-Phosphopantetheine and long acyl chain-dependent interactions are integral to human mitochondrial acyl carrier protein function JD Majmudar, X Feng, NG Fox, JF Nabhan, T Towle, T Ma, R Gooch, ... MedChemComm 10 (2), 209-220, 2019 | 30 | 2019 |
| Defined, serum-free conditions for in vitro culture of primary human T-ALL blasts AJ Yost, OO Shevchuk, R Gooch, S Gusscott, MJ You, TA Ince, JC Aster, ... Leukemia 27 (6), 1437-1440, 2013 | 25 | 2013 |
| Mitigation of peroxynitrite‐mediated nitric oxide (NO) toxicity as a mechanism of induced adaptive NO resistance in the CNS A Bishop, R Gooch, A Eguchi, S Jeffrey, L Smallwood, J Anderson, ... Journal of neurochemistry 109 (1), 74-84, 2009 | 16 | 2009 |
| Perturbation of cellular proteostasis networks identifies pathways that modulate precursor and intermediate but not mature levels of frataxin JF Nabhan, RL Gooch, EL Piatnitski Chekler, B Pierce, CE Bulawa Scientific Reports 5, 18251, 2015 | 15 | 2015 |
| Induced adaptive resistance to nitrooxidative stress in the CNS: therapeutic implications A Bishop, R Gooch, J Anderson Central Nervous System Agents in Medicinal Chemistry (Formerly Current …, 2006 | 1 | 2006 |
| A modified mouse model of Friedreich’s ataxia with conditional Fxn allele homozygosity delays onset of cardiomyopathy TL Perfitt, C Huichalaf, R Gooch, A Kuperman, Y Ahn, X Chen, S Ullas, ... American Journal of Physiology-Heart and Circulatory Physiology 326 (2 …, 2024 | | 2024 |
| New Insights into the Toxicity of AAV-Mediated Overexpression of Frataxin C Huichalaf, TL Perfitt, A Kuperman, R Gooch, RC Kovi, K Brenneman, ... MOLECULAR THERAPY 30 (4), 365-365, 2022 | | 2022 |
| Transient Correction of the Phenotype in a Cardiac Mouse Model of Friedreich Ataxia Using AAV9-CAG-FXN: Toxic Effect of Supraphysiological Expression of the Frataxin Transgene A Martelli, X Chen, B Assaf, T Ma, T Franks, W Laurence, R Gooch, ... MOLECULAR THERAPY 28 (4), 264-264, 2020 | | 2020 |
| Preclinical Evaluation of an AAV-Based Gene Therapy Approach for the Treatment of Friedreich Ataxia Cardiomyopathy A Martelli, BT Assaf, R Gooch, T Ma, LO Whiteley, C Bulawa MOLECULAR THERAPY 27 (4), 51-51, 2019 | | 2019 |
| Defined, Serum-Free Conditions for in Vitro culture of Primary Human T-ALL Blasts OO Shevchuk, AJ Yost, R Gooch, SD Gusscott, JM You, TA Ince, JC Aster, ... Blood 120 (21), 3537, 2012 | | 2012 |
| Induced Adaptive Resistance to Nitrooxidative Stress in the CNS: Thera-peutic Implications R Gooch, J Anderson, A Bishop | | |
| NO sensitivity on motor neurons: Comparison between differentiated and less differentiated cells KG Hobbs, R Gooch, R Chodimella, J Anderson, Y Hong, A Bishop | | |
| A Possible Mechanism of Induced Adaptive Resistance in Motor Neurons: Implications for CNS Injury and Disease R Gooch, A Bishop | | |
