Activation of canonical WNT/β-catenin signaling enhances in vitro motility of glioblastoma cells by activation of ZEB1 and other activators of epithelial-to-mesenchymal transition UD Kahlert, D Maciaczyk, S Doostkam, BA Orr, B Simons, T Bogiel, ... Cancer letters 325 (1), 42-53, 2012 | 251 | 2012 |
Epithelial-to-mesenchymal (-like) transition as a relevant molecular event in malignant gliomas UD Kahlert, G Nikkhah, J Maciaczyk Cancer letters 331 (2), 131-138, 2013 | 238 | 2013 |
BRAF activation induces transformation and then senescence in human neural stem cells: a pilocytic astrocytoma model EH Raabe, KS Lim, JM Kim, A Meeker, X Mao, G Nikkhah, J Maciaczyk, ... Clinical Cancer Research 17 (11), 3590-3599, 2011 | 205 | 2011 |
Glycolysis is the primary bioenergetic pathway for cell motility and cytoskeletal remodeling in human prostate and breast cancer cells T Shiraishi, JE Verdone, J Huang, UD Kahlert, JR Hernandez, G Torga, ... Oncotarget 6 (1), 130, 2015 | 187 | 2015 |
EMT‐and MET‐related processes in nonepithelial tumors: importance for disease progression, prognosis, and therapeutic opportunities UD Kahlert, JV Joseph, FAE Kruyt Molecular oncology 11 (7), 860-877, 2017 | 138 | 2017 |
LIN28A facilitates the transformation of human neural stem cells and promotes glioblastoma tumorigenesis through a pro-invasive genetic program X Mao, M Hütt-Cabezas, BA Orr, M Weingart, I Taylor, AKD Rajan, Y Odia, ... Oncotarget 4 (7), 1050, 2013 | 78 | 2013 |
ZEB1 promotes invasion in human fetal neural stem cells and hypoxic glioma neurospheres UD Kahlert, AK Suwala, EH Raabe, FA Siebzehnrubl, MJ Suarez, BA Orr, ... Brain pathology 25 (6), 724-732, 2015 | 77 | 2015 |
Pharmacologic Wnt inhibition reduces proliferation, survival, and clonogenicity of glioblastoma cells UD Kahlert, AK Suwala, K Koch, M Natsumeda, BA Orr, M Hayashi, ... Journal of neuropathology and experimental neurology 74 (9), 889-900, 2015 | 77 | 2015 |
A comparative pharmaco-metabolomic study of glutaminase inhibitors in glioma stem-like cells confirms biological effectiveness but reveals differences in target-specificity K Koch, R Hartmann, J Tsiampali, C Uhlmann, AC Nickel, X He, MA Kamp, ... Cell death discovery 6 (1), 20, 2020 | 67 | 2020 |
Targeting cancer stem‐like cells in glioblastoma and colorectal cancer through metabolic pathways UD Kahlert, SM Mooney, M Natsumeda, HJ Steiger, J Maciaczyk International Journal of Cancer 140 (1), 10-22, 2017 | 67 | 2017 |
Inhibition of Wnt/beta-catenin signaling downregulates expression of aldehyde dehydrogenase isoform 3A1 (ALDH3A1) to reduce resistance against temozolomide in glioblastoma in vitro AK Suwala, K Koch, DH Rios, P Aretz, C Uhlmann, I Ogorek, J Felsberg, ... Oncotarget 9 (32), 22703, 2018 | 66 | 2018 |
DiSCoVERing Innovative Therapies for Rare Tumors: Combining Genetically Accurate Disease Models with In Silico Analysis to Identify Novel Therapeutic Targets AR Hanaford, TC Archer, A Price, UD Kahlert, J Maciaczyk, G Nikkhah, ... Clinical Cancer Research 22 (15), 3903-3914, 2016 | 63 | 2016 |
Isoflurane enhances the malignant potential of glioblastoma stem cells by promoting their viability, mobility in vitro and migratory capacity in vivo M Zhu, M Li, Y Zhou, S Dangelmajer, UD Kahlert, R Xie, Q Xi, ... British journal of anaesthesia 116 (6), 870-877, 2016 | 57 | 2016 |
Targeting notch signaling and autophagy increases cytotoxicity in glioblastoma neurospheres M Natsumeda, K Maitani, Y Liu, H Miyahara, H Kaur, Q Chu, H Zhang, ... Brain pathology 26 (6), 713-723, 2016 | 51 | 2016 |
Clipping the wings of glioblastoma: modulation of WNT as a novel therapeutic strategy AK Suwala, A Hanaford, UD Kahlert, J Maciaczyk Journal of Neuropathology & Experimental Neurology 75 (5), 388-396, 2016 | 50 | 2016 |
Systemic inflammatory index is a novel predictor of intubation requirement and mortality after SARS-CoV-2 infection S Muhammad, I Fischer, S Naderi, M Faghih Jouibari, S Abdolreza, ... Pathogens 10 (1), 58, 2021 | 45 | 2021 |
CD133/CD15 defines distinct cell subpopulations with differential in vitro clonogenic activity and stem cell-related gene expression profile in in vitro propagated … UD Kahlert, NO Bender, D Maciaczyk, T Bogiel, EE Bar, CG Eberhart, ... Folia neuropathologica 50 (4), 357-368, 2012 | 44 | 2012 |
ALDH1A3 induces mesenchymal differentiation and serves as a predictor for survival in glioblastoma G Li, Y Li, X Liu, Z Wang, C Zhang, F Wu, H Jiang, W Zhang, Z Bao, ... Cell Death & Disease 9 (12), 1190, 2018 | 42 | 2018 |
Clinical characterization and immunosuppressive regulation of CD161 (KLRB1) in glioma through 916 samples W Di, W Fan, F Wu, Z Shi, Z Wang, M Yu, Y Zhai, Y Chang, C Pan, G Li, ... Cancer science 113 (2), 756-769, 2022 | 41 | 2022 |
CBF1 is clinically prognostic and serves as a target to block cellular invasion and chemoresistance of EMT-like glioblastoma cells D Maciaczyk, D Picard, L Zhao, K Koch, D Herrera-Rios, G Li, ... British journal of cancer 117 (1), 102-112, 2017 | 41 | 2017 |