Implication of tumor microenvironment in chemoresistance: tumor-associated stromal cells protect tumor cells from cell death M Castells, B Thibault, JP Delord, B Couderc International journal of molecular sciences 13 (8), 9545-9571, 2012 | 327 | 2012 |
Ovarian cancer microenvironment: implications for cancer dissemination and chemoresistance acquisition B Thibault, M Castells, JP Delord, B Couderc Cancer and Metastasis Reviews 33, 17-39, 2014 | 215 | 2014 |
Targeting PI3K signaling in combination cancer therapy E Pons-Tostivint, B Thibault, J Guillermet-Guibert Trends in cancer 3 (6), 454-469, 2017 | 141 | 2017 |
Microenvironment mesenchymal cells protect ovarian cancer cell lines from apoptosis by inhibiting XIAP inactivation M Castells, D Milhas, C Gandy, B Thibault, A Rafii, JP Delord, B Couderc Cell death & disease 4 (10), e887-e887, 2013 | 75 | 2013 |
DEBIO 1143, an IAP inhibitor, reverses carboplatin resistance in ovarian cancer cells and triggers apoptotic or necroptotic cell death B Thibault, L Genre, A Le Naour, C Broca, E Mery, G Vuagniaux, ... Scientific Reports 8 (1), 17862, 2018 | 58 | 2018 |
Tumor cells educate mesenchymal stromal cells to release chemoprotective and immunomodulatory factors A Le Naour, M Prat, B Thibault, R Mével, L Lemaitre, H Leray, MV Joubert, ... Journal of molecular cell biology 12 (3), 202-215, 2020 | 46 | 2020 |
Ovarian ascites-derived Hospicells promote angiogenesis via activation of macrophages M Castells, B Thibault, E Mery, M Golzio, M Pasquet, I Hennebelle, ... Cancer letters 326 (1), 59-68, 2012 | 45 | 2012 |
Evaluation of the effects of hyaluronic acid-carboxymethyl cellulose barrier on ovarian tumor progression L Picaud, B Thibault, E Mery, M Ouali, A Martinez, JP Delord, B Couderc, ... Journal of ovarian research 7, 1-12, 2014 | 32 | 2014 |
F14512, a polyamine-vectorized inhibitor of topoisomerase II, exhibits a marked anti-tumor activity in ovarian cancer B Thibault, E Clement, G Zorza, S Meignan, JP Delord, B Couderc, ... Cancer Letters 370 (1), 10-18, 2016 | 29 | 2016 |
Pancreatic cancer intrinsic PI3Kα activity accelerates metastasis and rewires macrophage component B Thibault, F Ramos‐Delgado, E Pons‐Tostivint, N Therville, C Cintas, ... EMBO molecular medicine 13 (7), e13502, 2021 | 27 | 2021 |
Fluorescence-guided surgery for cancer patients: a proof of concept study on human xenografts in mice and spontaneous tumors in pets E Mery, M Golzio, S Guillermet, D Lanore, A Le Naour, B Thibault, ... Oncotarget 8 (65), 109559, 2017 | 20 | 2017 |
Dasatinib+ Gefitinib, a non platinum-based combination with enhanced growth inhibitory, anti-migratory and anti-invasive potency against human ovarian cancer cells B Thibault, B Jean-Claude Journal of ovarian research 10, 1-12, 2017 | 19 | 2017 |
Organismal roles for the PI3Kα and β isoforms: Their specificity, redundancy or cooperation is context-dependent S Arcucci, F Ramos-Delgado, C Cayron, N Therville, MP Gratacap, ... Biochemical Journal 478 (6), 1199-1225, 2021 | 15 | 2021 |
Signal-targeted therapies and resistance mechanisms in pancreatic cancer: future developments reside in proteomics C Cintas, T Douché, N Therville, S Arcucci, F Ramos-Delgado, C Basset, ... Cancers 10 (6), 174, 2018 | 15 | 2018 |
Effect of combined inhibition of p110 alpha PI3K isoform and STAT3 pathway in ovarian cancer platinum-based resistance A Le Naour, R Mevel, B Thibault, E Courtais, E Chantalat, JP Delord, ... Oncotarget 9 (43), 27220, 2018 | 8 | 2018 |
Targeting class I-II-III PI3Ks in cancer therapy: recent advances in tumor biology and preclinical research B Thibault, F Ramos-Delgado, J Guillermet-Guibert Cancers 15 (3), 784, 2023 | 7 | 2023 |
Phosphoproteomics Identifies PI3K Inhibitor–Selective Adaptive Responses in Pancreatic Cancer Cell Therapy and Resistance C Cintas, T Douche, Z Dantes, E Mouton-Barbosa, MP Bousquet, ... Molecular Cancer Therapeutics 20 (12), 2433-2445, 2021 | 6 | 2021 |
Compressive constraint promotes the cytotoxicity of PI3K signal targeted therapies in breast and pancreatic cancer cells M Di-Luoffo, C Schmitter, EC Barrere, N Therville, M Chaouki, R D'Angelo, ... bioRxiv, 2023 | 4 | 2023 |
Mesenchymal stromal cells release CXCL1/2/8 and induce chemoresistance and macrophage polarization AL Naour, M Prat, B Thibault, R Mével, L Lemaitre, H Leray, M Golzio, ... bioRxiv, 482513, 2018 | 3 | 2018 |
Quantitative analysis of the potency of equimolar two-drug combinations and Combi-molecules involving kinase inhibitors in vitro: The concept of balanced targeting S Rao, B Thibault, L Peyrard, AL Larroque-Lombard, M Rupp, C Thauvin, ... International Journal of Molecular Sciences 22 (17), 9569, 2021 | 2 | 2021 |