Exploiting the enhanced permeability and retention effect for tumor targeting AK Iyer, G Khaled, J Fang, H Maeda Drug discovery today 11 (17-18), 812-818, 2006 | 2229 | 2006 |
Enhanced permeability and retention (EPR) effect for anticancer nanomedicine drug targeting K Greish Cancer nanotechnology: Methods and protocols, 25-37, 2010 | 981 | 2010 |
Enhanced permeability and retention of macromolecular drugs in solid tumors: a royal gate for targeted anticancer nanomedicines K Greish Journal of drug targeting 15 (7-8), 457-464, 2007 | 764 | 2007 |
Macromolecular therapeutics: advantages and prospects with special emphasis on solid tumour targeting K Greish, J Fang, T Inutsuka, A Nagamitsu, H Maeda Clinical pharmacokinetics 42 (13), 1089-1105, 2003 | 369 | 2003 |
Anticancer nanomedicine and tumor vascular permeability; Where is the missing link? S Taurin, H Nehoff, K Greish Journal of controlled release 164 (3), 265-275, 2012 | 356 | 2012 |
PEGylated PAMAM dendrimers: Enhancing efficacy and mitigating toxicity for effective anticancer drug and gene delivery D Luong, P Kesharwani, R Deshmukh, MCIM Amin, U Gupta, K Greish, ... Acta biomaterialia 43, 14-29, 2016 | 351 | 2016 |
Nanomedicine for drug targeting: strategies beyond the enhanced permeability and retention effect H Nehoff, NN Parayath, L Domanovitch, S Taurin, K Greish International journal of nanomedicine, 2539-2555, 2014 | 309 | 2014 |
In Vivo Antitumor Activity of Pegylated Zinc Protoporphyrin J Fang, T Sawa, T Akaike, T Akuta, SK Sahoo, G Khaled, A Hamada, ... Cancer research 63 (13), 3567, 2003 | 299 | 2003 |
SMA–doxorubicin, a new polymeric micellar drug for effective targeting to solid tumours K Greish, T Sawa, J Fang, T Akaike, H Maeda Journal of Controlled Release 97 (2), 219-230, 2004 | 244 | 2004 |
The EPR effect and polymeric drugs: a paradigm shift for cancer chemotherapy in the 21st century H Maeda, K Greish, J Fang Polymer therapeutics II, 103-121, 2006 | 235 | 2006 |
Influence of geometry, porosity, and surface characteristics of silica nanoparticles on acute toxicity: their vasculature effect and tolerance threshold T Yu, K Greish, LD McGill, A Ray, H Ghandehari ACS nano 6 (3), 2289-2301, 2012 | 229 | 2012 |
Enhancement of chemotherapeutic response of tumor cells by a heme oxygenase inhibitor, pegylated zinc protoporphyrin J Fang, T Sawa, T Akaike, K Greish, H Maeda International journal of cancer 109 (1), 1-8, 2004 | 224 | 2004 |
Elevating blood pressure as a strategy to increase tumor-targeted delivery of macromolecular drug SMANCS: cases of advanced solid tumors A Nagamitsu, K Greish, H Maeda Japanese journal of clinical oncology 39 (11), 756-766, 2009 | 214 | 2009 |
Size and surface charge significantly influence the toxicity of silica and dendritic nanoparticles K Greish, G Thiagarajan, H Herd, R Price, H Bauer, D Hubbard, A Burckle, ... Nanotoxicology 6 (7), 713-723, 2012 | 192 | 2012 |
Subchronic and chronic toxicity evaluation of inorganic nanoparticles for delivery applications R Mohammadpour, MA Dobrovolskaia, DL Cheney, KF Greish, ... Advanced drug delivery reviews 144, 112-132, 2019 | 164 | 2019 |
Polymeric micelles of zinc protoporphyrin for tumor targeted delivery based on EPR effect and singlet oxygen generation AK Iyer, K Greish, T Seki, S Okazaki, J Fang, K Takeshita, H Maeda Journal of drug targeting 15 (7-8), 496-506, 2007 | 145 | 2007 |
High-loading nanosized micelles of copoly (styrene–maleic acid)–zinc protoporphyrin for targeted delivery of a potent heme oxygenase inhibitor AK Iyer, K Greish, J Fang, R Murakami, H Maeda Biomaterials 28 (10), 1871-1881, 2007 | 123 | 2007 |
Copoly(styrene-maleic acid)−Pirarubicin Micelles: High Tumor-Targeting Efficiency with Little Toxicity1 K Greish, A Nagamitsu, J Fang, H Maeda Bioconjugate chemistry 16 (1), 230-236, 2005 | 121 | 2005 |
Charge affects the oral toxicity of poly (amidoamine) dendrimers G Thiagarajan, K Greish, H Ghandehari European Journal of Pharmaceutics and Biopharmaceutics 84 (2), 330-334, 2013 | 119 | 2013 |
Water-soluble polymer conjugates of ZnPP for photodynamic tumor therapy M Regehly, K Greish, F Rancan, H Maeda, F Böhm, B Röder Bioconjugate chemistry 18 (2), 494-499, 2007 | 112 | 2007 |