Single-cell transcriptomics of pancreatic cancer precursors demonstrates epithelial and microenvironmental heterogeneity as an early event in neoplastic progression V Bernard, A Semaan, J Huang, FA San Lucas, FC Mulu, BM Stephens, ... Clinical Cancer Research 25 (7), 2194-2205, 2019 | 312 | 2019 |
Hypoxia inducible factor (HIF) in the tumor microenvironment: friend or foe? Y Huang, D Lin, CM Taniguchi Science China Life Sciences 60, 1114-1124, 2017 | 142 | 2017 |
Mitochondrial fusion exploits a therapeutic vulnerability of pancreatic cancer M Yu, ND Nguyen, Y Huang, D Lin, TN Fujimoto, JM Molkentine, ... Jci Insight 4 (16), 2019 | 139 | 2019 |
Activation of Liver FGF21 in hepatocarcinogenesis and during hepatic stress C Yang, W Lu, T Lin, P You, M Ye, Y Huang, X Jiang, C Wang, F Wang, ... BMC gastroenterology 13, 1-14, 2013 | 125 | 2013 |
FRS2α-mediated FGF signals suppress premature differentiation of cardiac stem cells through regulating autophagy activity J Zhang, J Liu, Y Huang, JYF Chang, L Liu, WL McKeehan, JF Martin, ... Circulation research 110 (4), e29-e39, 2012 | 98 | 2012 |
Stromal HIF2 regulates immune suppression in the pancreatic cancer microenvironment CJG Garcia, Y Huang, NR Fuentes, MC Turner, ME Monberg, D Lin, ... Gastroenterology 162 (7), 2018-2031, 2022 | 84 | 2022 |
Type 1 fibroblast growth factor receptor in cranial neural crest cell-derived mesenchyme is required for palatogenesis C Wang, JYF Chang, C Yang, Y Huang, J Liu, P You, WL McKeehan, ... Journal of Biological Chemistry 288 (30), 22174-22183, 2013 | 66 | 2013 |
The FGF-BMP signaling axis regulates outflow tract valve primordium formation by promoting cushion neural crest cell differentiation J Zhang, JYF Chang, Y Huang, X Lin, Y Luo, RJ Schwartz, JF Martin, ... Circulation research 107 (10), 1209-1219, 2010 | 57 | 2010 |
Self-renewal and multilineage differentiation of mouse dental epithelial stem cells JYF Chang, C Wang, C Jin, C Yang, Y Huang, J Liu, WL McKeehan, ... Stem cell research 11 (3), 990-1002, 2013 | 49 | 2013 |
Selective EGLN inhibition enables ablative radiotherapy and improves survival in unresectable pancreatic cancer TN Fujimoto, LE Colbert, Y Huang, JM Molkentine, A Deorukhkar, ... Cancer research 79 (9), 2327-2338, 2019 | 39 | 2019 |
Hyperactivated FRS2α-mediated signaling in prostate cancer cells promotes tumor angiogenesis and predicts poor clinical outcome of patients J Liu, P You, G Chen, X Fu, X Zeng, C Wang, Y Huang, L An, X Wan, ... Oncogene 35 (14), 1750-1759, 2016 | 39 | 2016 |
Overexpression of FGF9 in Prostate Epithelial Cells Augments Reactive Stroma Formation and Promotes Prostate Cancer Progression. WF Huang Y, Jin C, Hamana T, Liu J, Wang C, An L, McKeehan WL Int J Biol Sci. 11 (8), 948-60., 2015 | 37 | 2015 |
Type 2 fibroblast growth factor receptor signaling preserves stemness and prevents differentiation of prostate stem cells from the basal compartment Y Huang, T Hamana, J Liu, C Wang, L An, P You, JYF Chang, J Xu, C Jin, ... Journal of Biological Chemistry 290 (29), 17753-17761, 2015 | 31 | 2015 |
Prostate sphere-forming stem cells are derived from the P63-expressing basal compartment Y Huang, T Hamana, J Liu, C Wang, L An, P You, JYF Chang, J Xu, ... Journal of Biological Chemistry 290 (29), 17745-17752, 2015 | 30 | 2015 |
Fibroblast growth factor signaling is essential for self-renewal of dental epithelial stem cells JYF Chang, C Wang, J Liu, Y Huang, C Jin, C Yang, B Hai, F Liu, ... Journal of Biological Chemistry 288 (40), 28952-28961, 2013 | 30 | 2013 |
The impact of FGFR1 and FRS2α expression on sorafenib treatment in metastatic renal cell carcinoma TH Ho, XD Liu, Y Huang, CL Warneke, MM Johnson, A Hoang, P Tamboli, ... BMC cancer 15, 1-7, 2015 | 22 | 2015 |
Overexpression of CD73 in pancreatic ductal adenocarcinoma is associated with immunosuppressive tumor microenvironment and poor survival J Zhao, LMS Soto, H Wang, MH Katz, LR Prakash, M Kim, CWD Tzeng, ... Pancreatology 21 (5), 942-949, 2021 | 21 | 2021 |
Resolving the HIF paradox in pancreatic cancer NR Fuentes, J Phan, Y Huang, D Lin, CM Taniguchi Cancer letters 489, 50-55, 2020 | 11 | 2020 |
FGFR1 abrogates inhibitory effect of androgen receptor concurrent with induction of androgen‐receptor variants in androgen receptor‐negative prostate tumor epithelial cells M Kobayashi, Y Huang, C Jin, Y Luo, T Okamoto, F Wang, WL McKeehan The Prostate 71 (15), 1691-1700, 2011 | 4 | 2011 |