Erythroferrone inhibits the induction of hepcidin by BMP6 J Arezes, N Foy, K McHugh, A Sawant, D Quinkert, V Terraube, A Brinth, ... Blood, The Journal of the American Society of Hematology 132 (14), 1473-1477, 2018 | 260 | 2018 |
Hepcidin-induced hypoferremia is a critical host defense mechanism against the siderophilic bacterium Vibrio vulnificus J Arezes, G Jung, V Gabayan, E Valore, P Ruchala, PA Gulig, T Ganz, ... Cell host & microbe 17 (1), 47-57, 2015 | 236 | 2015 |
Hepcidin and iron disorders: new biology and clinical approaches J Arezes, E Nemeth International journal of laboratory hematology 37, 92-98, 2015 | 143 | 2015 |
Endogenous hepcidin and its agonist mediate resistance to selected infections by clearing non–transferrin-bound iron D Stefanova, A Raychev, J Arezes, P Ruchala, V Gabayan, M Skurnik, ... Blood, The Journal of the American Society of Hematology 130 (3), 245-257, 2017 | 139 | 2017 |
Nrf2 controls iron homoeostasis in haemochromatosis and thalassaemia via Bmp6 and hepcidin PJ Lim, TL Duarte, J Arezes, D Garcia-Santos, A Hamdi, SR Pasricha, ... Nature Metabolism 1 (5), 519-531, 2019 | 112 | 2019 |
Hepcidin-mediated hypoferremia disrupts immune responses to vaccination and infection JN Frost, TK Tan, M Abbas, SK Wideman, M Bonadonna, NU Stoffel, ... Med 2 (2), 164-179. e12, 2021 | 92 | 2021 |
Hepcidin is regulated by promoter-associated histone acetylation and HDAC3 SR Pasricha, PJ Lim, TL Duarte, C Casu, D Oosterhuis, ... Nature communications 8 (1), 403, 2017 | 63 | 2017 |
Antibodies against the erythroferrone N-terminal domain prevent hepcidin suppression and ameliorate murine thalassemia J Arezes, N Foy, K McHugh, D Quinkert, S Benard, A Sawant, JN Frost, ... Blood, The Journal of the American Society of Hematology 135 (8), 547-557, 2020 | 58 | 2020 |
Transcriptomic profiling of the myeloma bone-lining niche reveals BMP signalling inhibition to improve bone disease S Gooding, SWZ Olechnowicz, EV Morris, AE Armitage, J Arezes, J Frost, ... Nature communications 10 (1), 4533, 2019 | 48 | 2019 |
Physiological implications of NTBI uptake by T lymphocytes JP Pinto, J Arezes, V Dias, S Oliveira, I Vieira, M Costa, M Vos, A Carlsson, ... Frontiers in pharmacology 5, 24, 2014 | 46 | 2014 |
Non-transferrin-bound iron (NTBI) uptake by T lymphocytes: evidence for the selective acquisition of oligomeric ferric citrate species J Arezes, M Costa, I Vieira, V Dias, XL Kong, R Fernandes, M Vos, ... PLoS One 8 (11), e79870, 2013 | 44 | 2013 |
Antiviral activity of bone morphogenetic proteins and activins LA Eddowes, K Al-Hourani, N Ramamurthy, J Frankish, HT Baddock, ... Nature microbiology 4 (2), 339-351, 2019 | 33 | 2019 |
Hepcidin-induced hypoferremia is a host-defense mechanism against siderophilic bacteria J Arezes, G Jung, V Gabayan, E Valore, T Ganz, Y Bulut, E Nemeth Blood 122 (21), 176, 2013 | 2 | 2013 |
Hepcidin Mediates Host Defense against Gram-Negative Pathogens by Controlling Non-Transferrin-Bound Iron D Stefanova, A Raychev, J Arezes, K Michels, B Dillon, M Horwitz, ... American Journal of Hematology 92 (8), E207-E207, 2017 | 1 | 2017 |
Methods of Treating Metabolic Disease AH Drakesmith, JAT Arezes, SJ Draper, KA McHugh, F Karpe, N Denton, ... US Patent App. 17/250,083, 2021 | | 2021 |
Antibodies Against the Erythroferrone N-Terminal Domain Prevent Hepcidin Suppression and Ameliorate Murine Thalassemia J Arezes, N Foy, S Benard, A Sawant, MS Tam, Z Maben, K McHugh, ... Blood 134, 964, 2019 | | 2019 |
THE HIGH-RESOLUTION CRYSTAL STRUCTURE OF THE GLOBULAR DOMAIN OF MOUSE ERFE K McHugh, J Jin, J Arezes, R Jasuja, A Drakesmith, S Draper, M Higgins AMERICAN JOURNAL OF HEMATOLOGY 92 (8), E425-E425, 2017 | | 2017 |
Red Cells, Iron, and Erythropoiesis: Endogenous hepcidin and its agonist mediate resistance to selected infections by clearing non–transferrin-bound iron D Stefanova, A Raychev, J Arezes, P Ruchala, V Gabayan, M Skurnik, ... Blood 130 (3), 245, 2017 | | 2017 |
Hepcidin Protects Against Extracellular Infections By Eliminating Non-Transferrin-Bound Iron D Stefanova, J Arezes, K Michels, B Dillon, M Horwitz, B Mehrad, Y Bulut, ... Blood 128 (22), 260, 2016 | | 2016 |
NON-TRANSFERRIN-BOUND IRON (NTBI) IS ESSENTIAL FOR RAPID GROWTH AND VIRULENCE OF VIBRIO VULNIFICUS J Arezes, D Stefanova, V Gabayan, Y Bulut, E Nemeth, T Ganz AMERICAN JOURNAL OF HEMATOLOGY 91 (3), E250-E250, 2016 | | 2016 |