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Joao Arezes
Joao Arezes
Senior Group Leader, UCB
在 ucb.com 的电子邮件经过验证 - 首页
标题
引用次数
引用次数
年份
Erythroferrone inhibits the induction of hepcidin by BMP6
J Arezes, N Foy, K McHugh, A Sawant, D Quinkert, V Terraube, A Brinth, ...
Blood, The Journal of the American Society of Hematology 132 (14), 1473-1477, 2018
2602018
Hepcidin-induced hypoferremia is a critical host defense mechanism against the siderophilic bacterium Vibrio vulnificus
J Arezes, G Jung, V Gabayan, E Valore, P Ruchala, PA Gulig, T Ganz, ...
Cell host & microbe 17 (1), 47-57, 2015
2362015
Hepcidin and iron disorders: new biology and clinical approaches
J Arezes, E Nemeth
International journal of laboratory hematology 37, 92-98, 2015
1432015
Endogenous hepcidin and its agonist mediate resistance to selected infections by clearing non–transferrin-bound iron
D Stefanova, A Raychev, J Arezes, P Ruchala, V Gabayan, M Skurnik, ...
Blood, The Journal of the American Society of Hematology 130 (3), 245-257, 2017
1392017
Nrf2 controls iron homoeostasis in haemochromatosis and thalassaemia via Bmp6 and hepcidin
PJ Lim, TL Duarte, J Arezes, D Garcia-Santos, A Hamdi, SR Pasricha, ...
Nature Metabolism 1 (5), 519-531, 2019
1122019
Hepcidin-mediated hypoferremia disrupts immune responses to vaccination and infection
JN Frost, TK Tan, M Abbas, SK Wideman, M Bonadonna, NU Stoffel, ...
Med 2 (2), 164-179. e12, 2021
922021
Hepcidin is regulated by promoter-associated histone acetylation and HDAC3
SR Pasricha, PJ Lim, TL Duarte, C Casu, D Oosterhuis, ...
Nature communications 8 (1), 403, 2017
632017
Antibodies against the erythroferrone N-terminal domain prevent hepcidin suppression and ameliorate murine thalassemia
J Arezes, N Foy, K McHugh, D Quinkert, S Benard, A Sawant, JN Frost, ...
Blood, The Journal of the American Society of Hematology 135 (8), 547-557, 2020
582020
Transcriptomic profiling of the myeloma bone-lining niche reveals BMP signalling inhibition to improve bone disease
S Gooding, SWZ Olechnowicz, EV Morris, AE Armitage, J Arezes, J Frost, ...
Nature communications 10 (1), 4533, 2019
482019
Physiological implications of NTBI uptake by T lymphocytes
JP Pinto, J Arezes, V Dias, S Oliveira, I Vieira, M Costa, M Vos, A Carlsson, ...
Frontiers in pharmacology 5, 24, 2014
462014
Non-transferrin-bound iron (NTBI) uptake by T lymphocytes: evidence for the selective acquisition of oligomeric ferric citrate species
J Arezes, M Costa, I Vieira, V Dias, XL Kong, R Fernandes, M Vos, ...
PLoS One 8 (11), e79870, 2013
442013
Antiviral activity of bone morphogenetic proteins and activins
LA Eddowes, K Al-Hourani, N Ramamurthy, J Frankish, HT Baddock, ...
Nature microbiology 4 (2), 339-351, 2019
332019
Hepcidin-induced hypoferremia is a host-defense mechanism against siderophilic bacteria
J Arezes, G Jung, V Gabayan, E Valore, T Ganz, Y Bulut, E Nemeth
Blood 122 (21), 176, 2013
22013
Hepcidin Mediates Host Defense against Gram-Negative Pathogens by Controlling Non-Transferrin-Bound Iron
D Stefanova, A Raychev, J Arezes, K Michels, B Dillon, M Horwitz, ...
American Journal of Hematology 92 (8), E207-E207, 2017
12017
Methods of Treating Metabolic Disease
AH Drakesmith, JAT Arezes, SJ Draper, KA McHugh, F Karpe, N Denton, ...
US Patent App. 17/250,083, 2021
2021
Antibodies Against the Erythroferrone N-Terminal Domain Prevent Hepcidin Suppression and Ameliorate Murine Thalassemia
J Arezes, N Foy, S Benard, A Sawant, MS Tam, Z Maben, K McHugh, ...
Blood 134, 964, 2019
2019
THE HIGH-RESOLUTION CRYSTAL STRUCTURE OF THE GLOBULAR DOMAIN OF MOUSE ERFE
K McHugh, J Jin, J Arezes, R Jasuja, A Drakesmith, S Draper, M Higgins
AMERICAN JOURNAL OF HEMATOLOGY 92 (8), E425-E425, 2017
2017
Red Cells, Iron, and Erythropoiesis: Endogenous hepcidin and its agonist mediate resistance to selected infections by clearing non–transferrin-bound iron
D Stefanova, A Raychev, J Arezes, P Ruchala, V Gabayan, M Skurnik, ...
Blood 130 (3), 245, 2017
2017
Hepcidin Protects Against Extracellular Infections By Eliminating Non-Transferrin-Bound Iron
D Stefanova, J Arezes, K Michels, B Dillon, M Horwitz, B Mehrad, Y Bulut, ...
Blood 128 (22), 260, 2016
2016
NON-TRANSFERRIN-BOUND IRON (NTBI) IS ESSENTIAL FOR RAPID GROWTH AND VIRULENCE OF VIBRIO VULNIFICUS
J Arezes, D Stefanova, V Gabayan, Y Bulut, E Nemeth, T Ganz
AMERICAN JOURNAL OF HEMATOLOGY 91 (3), E250-E250, 2016
2016
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