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Mridula Nambiar
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An inhibitor of nonhomologous end-joining abrogates double-strand break repair and impedes cancer progression
M Srivastava, M Nambiar, S Sharma, SS Karki, G Goldsmith, M Hegde, ...
Cell 151 (7), 1474-1487, 2012
4182012
Chromosomal translocations in cancer
M Nambiar, V Kari, SC Raghavan
Biochimica et Biophysica Acta (BBA)-Reviews on Cancer 1786 (2), 139-152, 2008
2342008
Novel derivatives of spirohydantoin induce growth inhibition followed by apoptosis in leukemia cells
CV Kavitha, M Nambiar, CSA Kumar, B Choudhary, K Muniyappa, ...
Biochemical pharmacology 77 (3), 348-363, 2009
1742009
How does DNA break during chromosomal translocations?
M Nambiar, SC Raghavan
Nucleic acids research 39 (14), 5813-5825, 2011
1592011
Formation of a G-quadruplex at the BCL2 major breakpoint region of the t(14;18) translocation in follicular lymphoma
M Nambiar, G Goldsmith, BT Moorthy, MR Lieber, MV Joshi, B Choudhary, ...
Nucleic acids research 39 (3), 936-948, 2011
1352011
Synthesis and biological evaluation of novel 2-aralkyl-5-substituted-6-(4′-fluorophenyl)-imidazo [2, 1-b][1, 3, 4] thiadiazole derivatives as potent anticancer agents
SS Karki, K Panjamurthy, S Kumar, M Nambiar, SA Ramareddy, ...
European journal of medicinal chemistry 46 (6), 2109-2116, 2011
1312011
Methyl angolensate, a natural tetranortriterpenoid induces intrinsic apoptotic pathway in leukemic cells
KK Chiruvella, V Kari, B Choudhary, M Nambiar, RG Ghanta, ...
FEBS letters 582 (29), 4066-4076, 2008
952008
Repression of harmful meiotic recombination in centromeric regions
M Nambiar, GR Smith
Seminars in cell & developmental biology 54, 188-197, 2016
922016
Potential G-quadruplex formation at breakpoint regions of chromosomal translocations in cancer may explain their fragility
VK Katapadi, M Nambiar, SC Raghavan
Genomics 100 (2), 72-80, 2012
902012
Anti-apoptotic protein BCL2 down-regulates DNA end joining in cancer cells
TS Kumar, V Kari, B Choudhary, M Nambiar, TS Akila, SC Raghavan
Journal of biological chemistry 285 (42), 32657-32670, 2010
602010
G-Quadruplex Structures Formed at the HOX11 Breakpoint Region Contribute to Its Fragility during t(10;14) Translocation in T-Cell Leukemia
M Nambiar, M Srivastava, V Gopalakrishnan, SK Sankaran, ...
Molecular and cellular biology 33 (21), 4266-4281, 2013
582013
A novel DNA intercalator, butylamino-pyrimido [4′, 5′: 4, 5] selenolo (2, 3-b) quinoline, induces cell cycle arrest and apoptosis in leukemic cells
MS Shahabuddin, M Nambiar, B Choudhary, GM Advirao, SC Raghavan
Investigational new drugs 28, 35-48, 2010
582010
Autocyclized and oxidized forms of SCR 7 induce cancer cell death by inhibiting nonhomologous DNA end joining in a Ligase IV dependent manner
SV Vartak, HA Swarup, V Gopalakrishnan, VK Gopinatha, V Ropars, ...
The FEBS journal 285 (21), 3959-3976, 2018
452018
Propyl-2-(8-(3, 4-difluorobenzyl)-2′, 5′-dioxo-8-azaspiro [bicyclo [3.2. 1] octane-3, 4′-imidazolidine]-1′-yl) acetate induces apoptosis in human leukemia cells through …
CV Kavitha, M Nambiar, PB Narayanaswamy, E Thomas, U Rathore, ...
PLoS One 8 (7), e69103, 2013
432013
Mechanism of fragility at BCL2 gene minor breakpoint cluster region during t (14; 18) chromosomal translocation
M Nambiar, SC Raghavan
Journal of Biological Chemistry 287 (12), 8688-8701, 2012
412012
Chromosomal translocations among the healthy human population: implications in oncogenesis
M Nambiar, SC Raghavan
Cellular and Molecular Life Sciences 70, 1381-1392, 2013
392013
Pericentromere-specific cohesin complex prevents meiotic pericentric DNA double-strand breaks and lethal crossovers
M Nambiar, GR Smith
Molecular cell 71 (4), 540-553. e4, 2018
362018
Detection of G-quadruplex DNA using primer extension as a tool
R Kumari, M Nambiar, S Shanbagh, SC Raghavan
PloS one 10 (3), e0119722, 2015
272015
A novel structural derivative of natural alkaloid ellipticine, MDPSQ, induces necrosis in leukemic cells
MS Shahabuddin, M Nambiar, BT Moorthy, PL Naik, B Choudhary, ...
Investigational new drugs 29, 523-533, 2011
242011
Prevalence and analysis of t (14; 18) and t (11; 14) chromosomal translocations in healthy Indian population
M Nambiar, SC Raghavan
Annals of hematology 89, 35-43, 2010
242010
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