| An Expanded Plasmid-Based Genetic Toolbox Enables Cas9 Genome Editing and Stable Maintenance of Synthetic Pathways in Phaeodactylum tricornutum SS Slattery, A Diamond, H Wang, JA Therrien, JT Lant, T Jazey, K Lee, ... ACS synthetic biology 7 (2), 328-338, 2018 | 151 | 2018 |
| Pathways to disease from natural variations in human cytoplasmic tRNAs JT Lant, MD Berg, IU Heinemann, CJ Brandl, P O’Donoghue Journal of Biological Chemistry 294 (14), 5294-5308, 2019 | 79 | 2019 |
| Biasing genome-editing events toward precise length deletions with an RNA-guided TevCas9 dual nuclease JM Wolfs, TA Hamilton, JT Lant, M Laforet, J Zhang, LM Salemi, GB Gloor, ... Proceedings of the National Academy of Sciences 113 (52), 14988-14993, 2016 | 51 | 2016 |
| Visualizing tRNA-dependent mistranslation in human cells JT Lant, MD Berg, DHW Sze, KS Hoffman, IC Akinpelu, MA Turk, ... RNA biology 15 (4-5), 567-575, 2018 | 45 | 2018 |
| Targeted sequencing reveals expanded genetic diversity of human transfer RNAs MD Berg, DJ Giguere, JS Dron, JT Lant, J Genereaux, C Liao, J Wang, ... RNA biology 16 (11), 1574-1585, 2019 | 35 | 2019 |
| Formation and persistence of polyglutamine aggregates in mistranslating cells JT Lant, R Kiri, ML Duennwald, P O’Donoghue Nucleic Acids Research 49 (20), 11883-11899, 2021 | 25 | 2021 |
| Phosphate-regulated expression of the SARS-CoV-2 receptor-binding domain in the diatom Phaeodactylum tricornutum for pandemic diagnostics SS Slattery, DJ Giguere, EE Stuckless, A Shrestha, LAK Briere, ... Scientific reports 12 (1), 7010, 2022 | 21 | 2022 |
| Energy/electron transfer switch for controlling optical properties of silicon quantum dots M Abdelhameed, S Aly, JT Lant, X Zhang, P Charpentier Scientific Reports 8 (1), 17068, 2018 | 17 | 2018 |
| Perseverance of protein homeostasis despite mistranslation of glycine codons with alanine F Hasan, JT Lant, P O'Donoghue Philosophical Transactions of the Royal Society B 378 (1871), 20220029, 2023 | 13 | 2023 |
| A novel fluorescent reporter sensitive to serine mis-incorporation P Rozik, R Szabla, JT Lant, R Kiri, DE Wright, M Junop, P O’Donoghue RNA biology 19 (1), 220-232, 2022 | 12 | 2022 |
| An expanded plas‑mid‑based genetic toolbox enables Cas9 genome editing and stable maintenance of synthetic pathways in Phaeodactylum tricornutum. ACS Synth Biol. 2018 SS Slattery, A Diamond, H Wang, JA Therrien, JT Lant, T Jazey, K Lee, ... | 8 | |
| Genetic interaction of tRNA-dependent mistranslation with fused in sarcoma protein aggregates JT Lant, F Hasan, J Briggs, IU Heinemann, P O’Donoghue Genes 14 (2), 518, 2023 | 3 | 2023 |
| P-TDHM: Open-source portable telecentric digital holographic microscope L Jin, Z Yu, A Au, P Serles, N Wang, JT Lant, T Filleter, CM Yip HardwareX 17, e00508, 2024 | | 2024 |
| Illuminating Transfer RNA Variants as Genetic Modifiers in Models of Human Disease JT Lant The University of Western Ontario (Canada), 2022 | | 2022 |
