Altered levels of cytokines and inflammatory mediators in plasma and leukocytes of sickle cell anemia patients and effects of hydroxyurea therapy C Lanaro, CF Franco-Penteado, DM Albuqueque, STO Saad, N Conran, ... Journal of Leucocyte Biology 85 (2), 235-242, 2009 | 239 | 2009 |
Inflammation in sickle cell disease N Conran, JD Belcher Clinical hemorheology and microcirculation 68 (2-3), 263-299, 2018 | 221 | 2018 |
Newer aspects of the pathophysiology of sickle cell disease vaso-occlusion N Conran, CF Franco-Penteado, FF Costa Hemoglobin 33 (1), 1-16, 2009 | 192 | 2009 |
Red cell DAMPs and inflammation R Mendonça, AAA Silveira, N Conran Inflammation Research 65, 665-678, 2016 | 156 | 2016 |
Hydroxyurea and a cGMP-amplifying agent have immediate benefits on acute vaso-occlusive events in sickle cell disease mice CB Almeida, C Scheiermann, JE Jang, C Prophete, FF Costa, N Conran, ... Blood, The Journal of the American Society of Hematology 120 (14), 2879-2888, 2012 | 127 | 2012 |
Increased adhesive properties of neutrophils in sickle cell disease may be reversed by pharmacological nitric oxide donation AA Canalli, CF Franco-Penteado, STO Saad, N Conran, FF Costa haematologica 93 (4), 605-609, 2008 | 93 | 2008 |
Acute hemolytic vascular inflammatory processes are prevented by nitric oxide replacement or a single dose of hydroxyurea CB Almeida, LEB Souza, FC Leonardo, FTM Costa, CC Werneck, ... Blood, The Journal of the American Society of Hematology 126 (6), 711-720, 2015 | 86 | 2015 |
Anemia falciforme FF Costa, N Conran, KY Fertrin Zago MA, Falcão RP, Pasquini R. Hematologia. Fundamentos e Prática. 1ª ed …, 2001 | 84 | 2001 |
Hemoglobin disorders and endothelial cell interactions N Conran, FF Costa Clinical biochemistry 42 (18), 1824-1838, 2009 | 77 | 2009 |
Increased soluble guanylate cyclase activity in the red blood cells of sickle cell patients N Conran, C Oresco‐Santos, HC Acosta, A Fattori, STO Saad, FF Costa British journal of haematology 124 (4), 547-554, 2004 | 76 | 2004 |
Increased levels of soluble ICAM‐1 in the plasma of sickle cell patients are reversed by hydroxyurea N Conran, A Fattori, STO Saad, FF Costa American journal of hematology 76 (4), 343-347, 2004 | 72 | 2004 |
Thromboinflammatory mechanisms in sickle cell disease–challenging the hemostatic balance N Conran, EV De Paula Haematologica 105 (10), 2380, 2020 | 65 | 2020 |
Effect of cytokines and chemokines on sickle neutrophil adhesion to fibronectin A Assis, N Conran, AA Canalli, I Lorand-Metze, STO Saad, FF Costa Acta haematologica 113 (2), 130-136, 2005 | 65 | 2005 |
Therapy with hydroxyurea is associated with reduced adhesion molecule gene and protein expression in sickle red cells with a concomitant reduction in adhesive properties S Gambero, AA Canalli, F Traina, DM Albuquerque, STO Saad, FF Costa, ... European journal of haematology 78 (2), 144-151, 2007 | 62 | 2007 |
Endothelial activation by platelets from sickle cell anemia patients R Proenca-Ferreira, AF Brugnerotto, VT Garrido, VM Dominical, DM Vital, ... PloS one 9 (2), e89012, 2014 | 61 | 2014 |
Leukocyte numbers correlate with plasma levels of granulocyte–macrophage colony-stimulating factor in sickle cell disease N Conran, STO Saad, FF Costa, T Ikuta Annals of Hematology 86, 255-261, 2007 | 59 | 2007 |
Hydroxyurea is associated with reductions in hypercoagulability markers in sickle cell anemia MP Colella, EV De Paula, N Conran, JA Machado‐Neto, ... Journal of Thrombosis and Haemostasis 10 (9), 1967-1970, 2012 | 56 | 2012 |
Nitric oxide has a role in regulating VLA-4-integrin expression on the human neutrophil cell surface N Conran, A Gambero, HHA Ferreira, E Antunes, G de Nucci Biochemical pharmacology 66 (1), 43-50, 2003 | 53 | 2003 |
Nitric oxide regulates human eosinophil adhesion mechanisms in vitro by changing integrin expression and activity on the eosinophil cell surface N Conran, HHA Ferreira, I Lorand‐Metze, SM Thomazzi, E Antunes, ... British journal of pharmacology 134 (3), 632-638, 2001 | 52 | 2001 |
Participation of Mac-1, LFA-1 and VLA-4 integrins in the in vitro adhesion of sickle cell disease neutrophils to endothelial layers, and reversal of adhesion by simvastatin AA Canalli, RF Proença, CF Franco-Penteado, F Traina, TM Sakamoto, ... Haematologica 96 (4), 526, 2011 | 49 | 2011 |