A structural basis for recognition of A· T and T· A base pairs in the minor groove of B-DNA CL Kielkopf, S White, JW Szewczyk, JM Turner, EE Baird, PB Dervan, ... Science 282 (5386), 111-115, 1998 | 447 | 1998 |
Structural basis for G• C recognition in the DNA minor groove CL Kielkopf, EE Baird, PB Dervan, DC Rees Nature structural biology 5 (2), 104-109, 1998 | 346 | 1998 |
U2AF homology motifs: protein recognition in the RRM world CL Kielkopf, S Lücke, MR Green Genes & development 18 (13), 1513-1526, 2004 | 302 | 2004 |
Bradford assay for determining protein concentration CL Kielkopf, W Bauer, IL Urbatsch Cold Spring Harbor Protocols 2020 (4), pdb. prot102269, 2020 | 280 | 2020 |
A novel peptide recognition mode revealed by the X-ray structure of a core U2AF35/U2AF65 heterodimer CL Kielkopf, NA Rodionova, MR Green, SK Burley Cell 106 (5), 595-605, 2001 | 246 | 2001 |
Structural basis for polypyrimidine tract recognition by the essential pre-mRNA splicing factor U2AF65 EA Sickmier, KE Frato, H Shen, SR Paranawithana, MR Green, ... Molecular cell 23 (1), 49-59, 2006 | 213 | 2006 |
Structure of a photoactive rhodium complex intercalated into DNA CL Kielkopf, KE Erkkila, BP Hudson, JK Barton, DC Rees Nature structural biology 7 (2), 117-121, 2000 | 168 | 2000 |
U2AF1 mutations alter sequence specificity of pre-mRNA binding and splicing T Okeyo-Owuor, BS White, R Chatrikhi, DR Mohan, S Kim, M Griffith, ... Leukemia 29 (4), 909-917, 2015 | 140 | 2015 |
Conformational flexibility of B-DNA at 0.74 Å resolution: d (CCAGTACTGG) 2 CL Kielkopf, S Ding, P Kuhn, DC Rees Journal of molecular biology 296 (3), 787-801, 2000 | 124 | 2000 |
Structural effects of DNA sequence on T· A recognition by hydroxypyrrole/pyrrole pairs in the minor groove CL Kielkopf, RE Bremer, S White, JW Szewczyk, JM Turner, EE Baird, ... Journal of molecular biology 295 (3), 557-567, 2000 | 118 | 2000 |
Structural basis for NADH/NAD+ redox sensing by a Rex family repressor KJ McLaughlin, CM Strain-Damerell, K Xie, D Brekasis, AS Soares, ... Molecular cell 38 (4), 563-575, 2010 | 117 | 2010 |
X-ray structure of a Rex-family repressor/NADH complex insights into the mechanism of redox sensing EA Sickmier, D Brekasis, S Paranawithana, JB Bonanno, MSB Paget, ... Structure 13 (1), 43-54, 2005 | 105 | 2005 |
Wild-type U2AF1 antagonizes the splicing program characteristic of U2AF1-mutant tumors and is required for cell survival DL Fei, H Motowski, R Chatrikhi, S Prasad, J Yu, S Gao, CL Kielkopf, ... PLoS Genetics 12 (10), e1006384, 2016 | 98 | 2016 |
Multiple U2AF65 binding sites within SF3b155: thermodynamic and spectroscopic characterization of protein–protein interactions among pre-mRNA splicing factors KR Thickman, MC Swenson, JM Kabogo, Z Gryczynski, CL Kielkopf Journal of molecular biology 356 (3), 664-683, 2006 | 75 | 2006 |
An extended U2AF65–RNA-binding domain recognizes the 3′ splice site signal AA Agrawal, E Salsi, R Chatrikhi, S Henderson, JL Jenkins, MR Green, ... Nature communications 7 (1), 10950, 2016 | 71 | 2016 |
Staufen1 dimerizes through a conserved motif and a degenerate dsRNA-binding domain to promote mRNA decay ML Gleghorn, C Gong, CL Kielkopf, LE Maquat Nature structural & molecular biology 20 (4), 515-524, 2013 | 69 | 2013 |
Major phosphorylation of SF1 on adjacent Ser‐Pro motifs enhances interaction with U2AF65 V Manceau, M Swenson, JP Le Caer, A Sobel, CL Kielkopf, A Maucuer The FEBS journal 273 (3), 577-587, 2006 | 69 | 2006 |
Splicing factor mutations in myelodysplasias: insights from spliceosome structures JL Jenkins, CL Kielkopf Trends in Genetics 33 (5), 336-348, 2017 | 60 | 2017 |
X-ray Structures of Threonine Aldolase Complexes: Structural Basis of Substrate Recognition, CL Kielkopf, SK Burley Biochemistry 41 (39), 11711-11720, 2002 | 60 | 2002 |
Cancer-relevant splicing factor CAPERα engages the essential splicing factor SF3b155 in a specific ternary complex S Loerch, A Maucuer, V Manceau, MR Green, CL Kielkopf Journal of Biological Chemistry 289 (25), 17325-17337, 2014 | 55 | 2014 |