| Commensals suppress intestinal epithelial cell retinoic acid synthesis to regulate interleukin-22 activity and prevent microbial dysbiosis M Grizotte-Lake, G Zhong, K Duncan, J Kirkwood, N Iyer, I Smolenski, ... Immunity 49 (6), 1103-1115. e6, 2018 | 168 | 2018 |
| Therapeutic applications of dichloroacetate and the role of glutathione transferase zeta-1 MO James, SC Jahn, G Zhong, MG Smeltz, Z Hu, PW Stacpoole Pharmacology & therapeutics 170, 166-180, 2017 | 134 | 2017 |
| Biochemical and physiological importance of the CYP26 retinoic acid hydroxylases N Isoherranen, G Zhong Pharmacology & therapeutics 204, 107400, 2019 | 81 | 2019 |
| Characterization of vitamin A metabolome in human livers with and without nonalcoholic fatty liver disease G Zhong, J Kirkwood, KJ Won, N Tjota, H Jeong, N Isoherranen Journal of Pharmacology and Experimental Therapeutics 370 (1), 92-103, 2019 | 50 | 2019 |
| CYP26C1 is a hydroxylase of multiple active retinoids and interacts with cellular retinoic acid binding proteins G Zhong, D Ortiz, A Zelter, A Nath, N Isoherranen Molecular pharmacology 93 (5), 489-503, 2018 | 35 | 2018 |
| The retinoic acid hydroxylase Cyp26a1 has minor effects on postnatal vitamin A homeostasis, but is required for exogenous atRA clearance G Zhong, C Hogarth, JM Snyder, L Palau, T Topping, W Huang, LC Czuba, ... Journal of Biological Chemistry 294 (29), 11166-11179, 2019 | 26 | 2019 |
| Gut commensals expand vitamin A metabolic capacity of the mammalian host M Bonakdar, LC Czuba, G Han, G Zhong, H Luong, N Isoherranen, ... Cell host & microbe 30 (8), 1084-1092. e5, 2022 | 25 | 2022 |
| Epithelium intrinsic vitamin A signaling co-ordinates pathogen clearance in the gut via IL-18 N Iyer, M Grizotte-Lake, K Duncan, SR Gordon, ACS Palmer, C Calvin, ... PLoS Pathogens 16 (4), e1008360, 2020 | 23 | 2020 |
| Sources of all-trans retinal oxidation independent of the aldehyde dehydrogenase 1A isozymes exist in the postnatal testis MT Beedle, F Stevison, G Zhong, T Topping, C Hogarth, N Isoherranen, ... Biology of reproduction 100 (2), 547-560, 2019 | 23 | 2019 |
| The influence of human GSTZ1 gene haplotype variations on GSTZ1 expression TY Langaee, G Zhong, W Li, I Hamadeh, MHM Solayman, ... Pharmacogenetics and genomics 25 (5), 239-245, 2015 | 22 | 2015 |
| Knockout of Cyp26a1 and Cyp26b1 during post-natal life causes reduced lifespan, dermatitis, splenomegaly and systemic inflammation in mice JM Snyder, G Zhong, C Hogarth, W Huang, T Topping, J LaFrance, ... FASEB journal: official publication of the Federation of American Societies …, 2020 | 21 | 2020 |
| Chloride and other anions inhibit dichloroacetate-induced inactivation of human liver GSTZ1 in a haplotype-dependent manner G Zhong, W Li, Y Gu, T Langaee, PW Stacpoole, MO James Chemico-biological interactions 215, 33-39, 2014 | 21 | 2014 |
| Pharmacokinetics of oral dichloroacetate in dogs HW Maisenbacher III, AL Shroads III, G Zhong, AD Daigle, ... Journal of biochemical and molecular toxicology 27 (12), 522-525, 2013 | 21 | 2013 |
| Aldehyde oxidase contributes to all-trans-retinoic acid biosynthesis in human liver G Zhong, CJ Seaman, EM Paragas, H Xi, KL Herpoldt, NP King, JP Jones, ... Drug Metabolism and Disposition 49 (3), 202-211, 2021 | 20 | 2021 |
| Discovery and Visualization of Uncharacterized Drug–Protein Adducts Using Mass Spectrometry M Riffle, MR Hoopmann, D Jaschob, G Zhong, RL Moritz, MJ MacCoss, ... Analytical chemistry 94 (8), 3501-3509, 2022 | 14 | 2022 |
| Impact of vitamin A transport and storage on intestinal retinoid homeostasis and functions M Honarbakhsh, A Ericsson, G Zhong, N Isoherranen, C Zhu, Y Bromberg, ... Journal of lipid research 62, 2021 | 14 | 2021 |
| Scaling in vitro activity of CYP3A7 suggests human fetal livers do not clear retinoic acid entering from maternal circulation AR Topletz, G Zhong, N Isoherranen Scientific Reports 9 (1), 4620, 2019 | 14 | 2019 |
| Analysis of vitamin A and retinoids in biological matrices LC Czuba, G Zhong, KC Yabut, N Isoherranen Methods in enzymology 637, 309-340, 2020 | 13 | 2020 |
| Regulation of dichloroacetate biotransformation in rat liver and extrahepatic tissues by GSTZ1 expression and chloride concentration SC Jahn, MG Smeltz, Z Hu, L Rowland-Faux, G Zhong, RJ Lorenzo, ... Biochemical pharmacology 152, 236-243, 2018 | 7 | 2018 |
| Age-Related Changes in Expression and Activity of Human Hepatic Mitochondrial Glutathione Transferase Zeta1 G Zhong, MO James, MG Smeltz, SC Jahn, TY Langaee, P Simpson, ... Drug Metabolism and Disposition 46 (8), 1118-1128, 2018 | 7 | 2018 |
