Interplay of IKK/NF-κB signaling in macrophages and myofibers promotes muscle degeneration in Duchenne muscular dystrophy S Acharyya, SA Villalta, N Bakkar, T Bupha-Intr, PML Janssen, ... The Journal of clinical investigation 117 (4), 889-901, 2007 | 534 | 2007 |
NF-κB regulation of YY1 inhibits skeletal myogenesis through transcriptional silencing of myofibrillar genes H Wang, E Hertlein, N Bakkar, H Sun, S Acharyya, J Wang, M Carathers, ... Molecular and cellular biology 27 (12), 4374-4387, 2007 | 292 | 2007 |
IKK/NF-κB regulates skeletal myogenesis via a signaling switch to inhibit differentiation and promote mitochondrial biogenesis N Bakkar, J Wang, KJ Ladner, H Wang, JM Dahlman, M Carathers, ... The Journal of cell biology 180 (4), 787-802, 2008 | 255 | 2008 |
NF-κB signaling: a tale of two pathways in skeletal myogenesis N Bakkar, DC Guttridge Physiological reviews 90 (2), 495-511, 2010 | 245 | 2010 |
Artificial intelligence in neurodegenerative disease research: use of IBM Watson to identify additional RNA-binding proteins altered in amyotrophic lateral sclerosis N Bakkar, T Kovalik, I Lorenzini, S Spangler, A Lacoste, K Sponaugle, ... Acta neuropathologica 135, 227-247, 2018 | 175 | 2018 |
NF-kB Signaling in Skeletal Muscle Health and Disease JM Peterson, N Bakkar, DC Guttridge Current topics in developmental biology 96, 85, 2011 | 170 | 2011 |
Tau aggregates are RNA-protein assemblies that mislocalize multiple nuclear speckle components E Lester, FK Ooi, N Bakkar, J Ayers, AL Woerman, J Wheeler, R Bowser, ... Neuron 109 (10), 1675-1691. e9, 2021 | 129 | 2021 |
Modulating cell cycle: current applications and prospects for future drug development. H Gali-Muhtasib, N Bakkar Curr Cancer Drug Targets 2 (4), 309-336, 2002 | 114 | 2002 |
ALS associated mutations in Matrin 3 alter protein-protein interactions and impede mRNA nuclear export A Boehringer, K Garcia-Mansfield, G Singh, N Bakkar, P Pirrotte, ... Scientific reports 7 (1), 14529, 2017 | 102 | 2017 |
miR-29 acts as a decoy in sarcomas to protect the tumor suppressor A20 mRNA from degradation by HuR MY Balkhi, OH Iwenofu, N Bakkar, KJ Ladner, DS Chandler, PJ Houghton, ... Science signaling 6 (286), ra63-ra63, 2013 | 97 | 2013 |
IKKα and alternative NF-κB regulate PGC-1β to promote oxidative muscle metabolism N Bakkar, K Ladner, BD Canan, S Liyanarachchi, NC Bal, M Pant, ... Journal of Cell Biology 196 (4), 497-511, 2012 | 89 | 2012 |
The RelA/p65 subunit of NF‐κB specifically regulates cyclin D1 protein stability: Implications for cell cycle withdrawal and skeletal myogenesis JM Dahlman, J Wang, N Bakkar, DC Guttridge Journal of cellular biochemistry 106 (1), 42-51, 2009 | 58 | 2009 |
Use of biomarkers in ALS drug development and clinical trials. N Bakkar, A Boehringer, R Bowser Brain Research 1607, 94-107, 2015 | 51 | 2015 |
RelA/p65 regulation of IκBβ E Hertlein, J Wang, KJ Ladner, N Bakkar, DC Guttridge Molecular and cellular biology 25 (12), 4956-4968, 2005 | 48 | 2005 |
Global alterations to the choroid plexus blood-CSF barrier in amyotrophic lateral sclerosis J Saul, E Hutchins, R Reiman, M Saul, LW Ostrow, BT Harris, ... Acta Neuropathologica Communications 8, 1-21, 2020 | 46 | 2020 |
NF-κB inhibition rescues cardiac function by remodeling calcium genes in a Duchenne muscular dystrophy model JM Peterson, DJ Wang, V Shettigar, SR Roof, BD Canan, N Bakkar, ... Nature communications 9 (1), 3431, 2018 | 38 | 2018 |
RBM45 homo-oligomerization mediates association with ALS-linked proteins and stress granules Y Li, M Collins, R Geiser, N Bakkar, D Riascos, R Bowser Scientific reports 5 (1), 14262, 2015 | 35 | 2015 |
NF-κB functions in stromal fibroblasts to regulate early postnatal muscle development JM Dahlman, N Bakkar, W He, DC Guttridge Journal of Biological Chemistry 285 (8), 5479-5487, 2010 | 35 | 2010 |
RBM45 modulates the antioxidant response in ALS through interactions with KEAP1. N Bakkar, A Kousari, T Kovalik, Y Li, R Bowser Mol Cell Biol, 2015 | 29 | 2015 |
Effects of nimodipine on the behavioral sequalae of experimental status epilepticus in prepubescent rats. MA Mikati, GL Holmes, Werner, S, N Bakkar, L Carmant, Z Liu, ... Epilepsy & Behavior 5 (2), 168-174, 2004 | 28 | 2004 |