Forelimb treatment in a large cohort of dystrophic dogs supports delivery of a recombinant AAV for exon skipping in Duchenne patients C Le Guiner, M Montus, L Servais, Y Cherel, V Francois, JL Thibaud, ... Molecular Therapy 22 (11), 1923-1935, 2014 | 134 | 2014 |
Safety and efficacy of regional intravenous (ri) versus intramuscular (im) delivery of rAAV1 and rAAV8 to nonhuman primate skeletal muscle A Toromanoff, Y Chérel, M Guilbaud, M Penaud-Budloo, RO Snyder, ... Molecular Therapy 16 (7), 1291-1299, 2008 | 102 | 2008 |
Chemical modification of the adeno-associated virus capsid to improve gene delivery M Mével, M Bouzelha, A Leray, S Pacouret, M Guilbaud, ... Chemical science 11 (4), 1122-1131, 2020 | 65 | 2020 |
Transgene regulation using the tetracycline-inducible TetR-KRAB system after AAV-mediated gene transfer in rodents and nonhuman primates C Le Guiner, K Stieger, A Toromanoff, M Guilbaud, A Mendes-Madeira, ... PloS one 9 (9), e102538, 2014 | 45 | 2014 |
Five years of successful inducible transgene expression following locoregional adeno-associated virus delivery in nonhuman primates with no detectable immunity M Guilbaud, M Devaux, C Couzinie, J Le Duff, A Toromanoff, ... Human Gene Therapy 30 (7), 802-813, 2019 | 40 | 2019 |
The cellular TATA binding protein is required for rep-dependent replication of a minimal adeno-associated virus type 2 p5 element A François, M Guilbaud, R Awedikian, G Chadeuf, P Moullier, A Salvetti Journal of virology 79 (17), 11082-11094, 2005 | 35 | 2005 |
Tetramer-Based Enrichment of Preexisting Anti-AAV8 CD8+ T Cells in Human Donors Allows the Detection of a TEMRA Subpopulation C Vandamme, R Xicluna, L Hesnard, M Devaux, N Jaulin, M Guilbaud, ... Frontiers in immunology 10, 3110, 2020 | 23 | 2020 |
Generation and in vivo evaluation of IL10-treated dendritic cells in a nonhuman primate model of AAV-based gene transfer A Moreau, C Vandamme, M Segovia, M Devaux, M Guilbaud, G Tilly, ... Molecular therapy Methods & clinical development 1, 2014 | 21 | 2014 |
Early interaction of adeno-associated virus serotype 8 vector with the host immune system following intramuscular delivery results in weak but detectable lymphocyte and … G Gernoux, M Guilbaud, L Dubreil, T Larcher, C Babarit, M Ledevin, ... Human gene therapy 26 (1), 1-13, 2015 | 17 | 2015 |
Intrathymic adeno-associated virus gene transfer rapidly restores thymic function and long-term persistence of gene-corrected T cells M Pouzolles, A Machado, M Guilbaud, M Irla, S Gailhac, P Barennes, ... Journal of Allergy and Clinical Immunology 145 (2), 679-697. e5, 2020 | 12 | 2020 |
Intracellular route and biological activity of exogenously delivered Rep proteins from the adeno-associated virus type 2 R Awedikian, A François, M Guilbaud, P Moullier, A Salvetti Virology 335 (2), 252-263, 2005 | 10 | 2005 |
Relative influence of the adeno-associated virus (AAV) type 2 p5 element for recombinant AAV vector site-specific integration M Guilbaud, G Chadeuf, F Avolio, A François, P Moullier, A Recchia, ... Journal of virology 82 (5), 2590-2593, 2008 | 9 | 2008 |
Novel chemical tyrosine functionalization of adeno-associated virus improves gene transfer efficiency in liver and retina A Leray, PA Lalys, J Varin, M Bouzelha, A Bourdon, D Alvarez-Dorta, ... Biomedicine & Pharmacotherapy 171, 116148, 2024 | 6 | 2024 |
Intrathymic AAV delivery results in therapeutic site-specific integration at TCR loci in mice A Calabria, C Cipriani, G Spinozzi, L Rudilosso, S Esposito, F Benedicenti, ... Blood, The Journal of the American Society of Hematology 141 (19), 2316-2329, 2023 | 6 | 2023 |
AAV8 locoregional delivery induces long-term expression of an immunogenic transgene in macaques despite persisting local inflammation G Gernoux, M Guilbaud, M Devaux, M Journou, V Pichard, N Jaulin, ... Molecular Therapy-Methods & Clinical Development 20, 660-674, 2021 | 6 | 2021 |
Prevalence Study of Cellular Capsid-Specific Immune Responses to AAV2, 4, 5, 8, 9, and rh10 in Healthy Donors R Xicluna, A Avenel, C Vandamme, M Devaux, N Jaulin, C Couzinie, ... Human Gene Therapy 35 (9-10), 355-364, 2024 | 1 | 2024 |
Transcriptomic Analysis Reveals the Inability of Recombinant AAV8 to Activate Human Monocyte-Derived Dendritic Cells S Masri, L Carré, N Jaulin, C Vandamme, C Couzinié, A Guy-Duché, ... International Journal of Molecular Sciences 24 (13), 10447, 2023 | 1 | 2023 |
Phenotypic and functional characterisation of human anti-AAV CD8+ T cells using MHC class I tetramer-associated magnetic enrichment C Vandamme, M Devaux, N Jaulin, M Guilbaud, J Le Duff, L Hesnard, ... MOLECULAR THERAPY 24, S275-S276, 2016 | 1 | 2016 |
697. Phenotypic and Functional Characterisation of Human Anti-AAV CD8+ T Cells Using MHC Class I Tetramer-Associated Magnetic Enrichment C Vandamme, M Devaux, N Jaulin, M Guilbaud, J Le Duff, L Hesnard, ... Molecular Therapy 24, S275-S276, 2016 | 1 | 2016 |
GP 92: Persistence and stability at 6 months of AAV genome and dystrophin expression in GRMD dogs after forelimb delivery of a recombinant AAV carrying an exon skipping sequence L Servais, C Le Guiner, M Montus, Y Cherel, V Francois, JL Thibaud, ... Neuromuscular Disorders 24 (9), 822, 2014 | 1 | 2014 |