Oncogenic KRAS signalling in pancreatic cancer S Eser, A Schnieke, G Schneider, D Saur British journal of cancer 111 (5), 817-822, 2014 | 629 | 2014 |
Pancreatic ductal adenocarcinoma: biological hallmarks, current status, and future perspectives of combined modality treatment approaches M Orth, P Metzger, S Gerum, J Mayerle, G Schneider, C Belka, M Schnurr, ... Radiation Oncology 14 (1), 1-20, 2019 | 473 | 2019 |
E-cadherin regulates metastasis of pancreatic cancer in vivo and is suppressed by a SNAIL/HDAC1/HDAC2 repressor complex J Von Burstin, S Eser, MC Paul, B Seidler, M Brandl, M Messer, ... Gastroenterology 137 (1), 361-371. e5, 2009 | 432 | 2009 |
Pancreatic cancer: basic and clinical aspects G Schneider, JT Siveke, F Eckel, RM Schmid Gastroenterology 128 (6), 1606-1625, 2005 | 399 | 2005 |
Selective requirement of PI3K/PDK1 signaling for Kras oncogene-driven pancreatic cell plasticity and cancer S Eser, N Reiff, M Messer, B Seidler, K Gottschalk, M Dobler, M Hieber, ... Cancer cell 23 (3), 406-420, 2013 | 396 | 2013 |
Evolutionary routes and KRAS dosage define pancreatic cancer phenotypes S Mueller, T Engleitner, R Maresch, M Zukowska, S Lange, ... Nature 554 (7690), 62-68, 2018 | 387 | 2018 |
Combined inhibition of BET family proteins and histone deacetylases as a potential epigenetics-based therapy for pancreatic ductal adenocarcinoma PK Mazur, A Herner, SS Mello, M Wirth, S Hausmann, FJ Sánchez-Rivera, ... Nature medicine 21 (10), 1163-1171, 2015 | 379 | 2015 |
Tissue-specific tumorigenesis: context matters G Schneider, M Schmidt-Supprian, R Rad, D Saur Nature Reviews Cancer 17 (4), 239-253, 2017 | 287 | 2017 |
CXCR4 expression increases liver and lung metastasis in a mouse model of pancreatic cancer D Saur, B Seidler, G Schneider, H Algül, R Beck, ... Gastroenterology 129 (4), 1237-1250, 2005 | 282 | 2005 |
A next-generation dual-recombinase system for time-and host-specific targeting of pancreatic cancer N Schönhuber, B Seidler, K Schuck, C Veltkamp, C Schachtler, ... Nature medicine 20 (11), 1340-1347, 2014 | 247 | 2014 |
A genetic progression model of BrafV600E-induced intestinal tumorigenesis reveals targets for therapeutic intervention R Rad, J Cadiñanos, L Rad, I Varela, A Strong, L Kriegl, ... Cancer cell 24 (1), 15-29, 2013 | 245 | 2013 |
Interstitial cells of Cajal integrate excitatory and inhibitory neurotransmission with intestinal slow-wave activity S Klein, B Seidler, A Kettenberger, A Sibaev, M Rohn, R Feil, ... Nature communications 4 (1), 1630, 2013 | 219 | 2013 |
CRISPR/Cas9 somatic multiplex-mutagenesis for high-throughput functional cancer genomics in mice J Weber, R Öllinger, M Friedrich, U Ehmer, M Barenboim, K Steiger, I Heid, ... Proceedings of the National Academy of Sciences 112 (45), 13982-13987, 2015 | 218 | 2015 |
Stat3 and NF-κB activation prevents apoptosis in pancreatic carcinogenesis FR Greten, CK Weber, TF Greten, G Schneider, M Wagner, G Adler, ... Gastroenterology 123 (6), 2052-2063, 2002 | 206 | 2002 |
Genetic alterations in pancreatic carcinoma G Schneider, RM Schmid Molecular cancer 2, 1-7, 2003 | 200 | 2003 |
Multiplexed pancreatic genome engineering and cancer induction by transfection-based CRISPR/Cas9 delivery in mice R Maresch, S Mueller, C Veltkamp, R Öllinger, M Friedrich, I Heid, ... Nature communications 7 (1), 10770, 2016 | 199 | 2016 |
HDAC2 mediates therapeutic resistance of pancreatic cancer cells via the BH3-only protein NOXA P Fritsche, B Seidler, S Schüler, A Schnieke, M Göttlicher, RM Schmid, ... Gut 58 (10), 1399-1409, 2009 | 199 | 2009 |
Cross talk between stimulated NF-κB and the tumor suppressor p53 G Schneider, A Henrich, G Greiner, V Wolf, A Lovas, M Wieczorek, ... Oncogene 29 (19), 2795-2806, 2010 | 185 | 2010 |
Apoptotic pathways in pancreatic ductal adenocarcinoma R Hamacher, RM Schmid, D Saur, G Schneider Molecular cancer 7, 1-10, 2008 | 182 | 2008 |
A Cre-loxP-based mouse model for conditional somatic gene expression and knockdown in vivo by using avian retroviral vectors B Seidler, A Schmidt, U Mayr, H Nakhai, RM Schmid, G Schneider, D Saur Proceedings of the National Academy of Sciences 105 (29), 10137-10142, 2008 | 170 | 2008 |