Neurotoxicity of a prion protein fragment G Forloni, N Angeretti, R Chiesa, E Monzani, M Salmona, O Bugiani, ... Nature 362 (6420), 543-546, 1993 | 1152 | 1993 |
Synthetic amyloid-β oligomers impair long-term memory independently of cellular prion protein C Balducci, M Beeg, M Stravalaci, A Bastone, A Sclip, E Biasini, L Tapella, ... Proceedings of the National Academy of Sciences 107 (5), 2295-2300, 2010 | 593 | 2010 |
Apoptosis mediated neurotoxicity induced by chronic application of β amyloid fragment 25–35 G Forloni, R Chiesa, S Smiroldo, L Verga, M Salmona, F Tagliavini, ... Neuroreport 4 (5), 523-526, 1993 | 424 | 1993 |
Neurological illness in transgenic mice expressing a prion protein with an insertional mutation R Chiesa, P Piccardo, B Ghetti, DA Harris Neuron 21 (6), 1339-1351, 1998 | 383 | 1998 |
Mutant PrP is delayed in its exit from the endoplasmic reticulum, but neither wild-type nor mutant PrP undergoes retrotranslocation prior to proteasomal degradation B Drisaldi, RS Stewart, C Adles, LR Stewart, E Quaglio, E Biasini, L Fioriti, ... Journal of Biological Chemistry 278 (24), 21732-21743, 2003 | 285 | 2003 |
Neonatal lethality in transgenic mice expressing prion protein with a deletion of residues 105–125 A Li, HM Christensen, LR Stewart, KA Roth, R Chiesa, DA Harris The EMBO journal 26 (2), 548-558, 2007 | 256 | 2007 |
Evidence for a six-transmembrane domain structure of presenilin 1 S Lehmann, R Chiesa, DA Harris Journal of Biological Chemistry 272 (18), 12047-12051, 1997 | 223 | 1997 |
Copper converts the cellular prion protein into a protease-resistant species that is distinct from the scrapie isoform E Quaglio, R Chiesa, DA Harris Journal of Biological Chemistry 276 (14), 11432, 2001 | 222 | 2001 |
Prion diseases: what is the neurotoxic molecule? R Chiesa, DA Harris Neurobiology of disease 8 (5), 743-763, 2001 | 210 | 2001 |
Accumulation of protease-resistant prion protein (PrP) and apoptosis of cerebellar granule cells in transgenic mice expressing a PrP insertional mutation R Chiesa, B Drisaldi, E Quaglio, A Migheli, P Piccardo, B Ghetti, DA Harris Proceedings of the National Academy of Sciences 97 (10), 5574-5579, 2000 | 192 | 2000 |
Molecular distinction between pathogenic and infectious properties of the prion protein R Chiesa, P Piccardo, E Quaglio, B Drisaldi, SL Si-Hoe, M Takao, B Ghetti, ... Journal of virology 77 (13), 7611-7622, 2003 | 176 | 2003 |
Monoclonal antibodies to human DNA topoisomerase I and the two isoforms of DNA topoisomerase II: 170-and 180-kDa isozymes C Negri, R Chiesa, A Cerino, M Bestagno, C Sala, N Zini, NM Maraldi, ... Experimental cell research 200 (2), 452-459, 1992 | 149 | 1992 |
Induction of a transmissible tau pathology by traumatic brain injury ER Zanier, I Bertani, E Sammali, F Pischiutta, MA Chiaravalloti, ... Brain 141 (9), 2685-2699, 2018 | 145 | 2018 |
Conditions of endoplasmic reticulum stress favor the accumulation of cytosolic prion protein A Orsi, L Fioriti, R Chiesa, R Sitia Journal of Biological Chemistry 281 (41), 30431-30438, 2006 | 140 | 2006 |
Cytosolic prion protein (PrP) is not toxic in N2a cells and primary neurons expressing pathogenic PrP mutations L Fioriti, S Dossena, LR Stewart, RS Stewart, DA Harris, G Forloni, ... Journal of Biological Chemistry 280 (12), 11320-11328, 2005 | 138 | 2005 |
A neurotoxic prion protein fragment induces rat astroglial proliferation and hypertrophy G Forloni, R Del Bo, N Angeretti, R Chiesa, S Smiroldo, R Doni, ... European Journal of Neuroscience 6 (9), 1415-1422, 1994 | 135 | 1994 |
Mutant prion protein expression causes motor and memory deficits and abnormal sleep patterns in a transgenic mouse model S Dossena, L Imeri, M Mangieri, A Garofoli, L Ferrari, A Senatore, ... Neuron 60 (4), 598-609, 2008 | 128 | 2008 |
Bax deletion prevents neuronal loss but not neurological symptoms in a transgenic model of inherited prion disease R Chiesa, P Piccardo, S Dossena, L Nowoslawski, KA Roth, B Ghetti, ... Proceedings of the National Academy of Sciences 102 (1), 238-243, 2005 | 114 | 2005 |
Proteasome inhibition and aggregation in Parkinson's disease: a comparative study in untransfected and transfected cells E Biasini, L Fioriti, I Ceglia, R Invernizzi, A Bertoli, R Chiesa, G Forloni Journal of neurochemistry 88 (3), 545-553, 2004 | 89 | 2004 |
Mutant PrP suppresses glutamatergic neurotransmission in cerebellar granule neurons by impairing membrane delivery of VGCC α2δ-1 subunit A Senatore, S Colleoni, C Verderio, E Restelli, R Morini, SB Condliffe, ... Neuron 74 (2), 300-313, 2012 | 79 | 2012 |