Probing the β-pocket of the active site of human liver glycogen phosphorylase with 3-(C-β-d-glucopyranosyl)-5-(4-substituted-phenyl)-1, 2, 4-triazole inhibitors E Kyriakis, TGA Solovou, S Kun, K Czifrák, B Szőcs, L Juhász, É Bokor, ... Bioorganic chemistry 77, 485-493, 2018 | 28 | 2018 |
Nanomolar Inhibitors of Glycogen Phosphorylase Based on β-d-Glucosaminyl Heterocycles: A Combined Synthetic, Enzyme Kinetic, and Protein Crystallography … E Bokor, E Kyriakis, TGA Solovou, C Koppany, AL Kantsadi, KE Szabo, ... Journal of medicinal chemistry 60 (22), 9251-9262, 2017 | 25 | 2017 |
van der Waals interactions govern C-β-D-glucopyranosyl triazoles’ nM inhibitory potency in human liver glycogen phosphorylase AL Kantsadi, GA Stravodimos, E Kyriakis, DSM Chatzileontiadou, ... Journal of Structural Biology 199 (1), 57-67, 2017 | 20 | 2017 |
Affinity crystallography reveals the bioactive compounds of industrial juicing byproducts of Punica granatum for glycogen phosphorylase GA Stravodimos, AL Kantsadi, A Apostolou, E Kyriakis, VN Kafaski-Kanelli, ... Current drug discovery technologies 15 (1), 41-53, 2018 | 8 | 2018 |
The architecture of hydrogen and sulfur σ-hole interactions explain differences in the inhibitory potency of C-β-d-glucopyranosyl thiazoles, imidazoles and an N-β-d … E Kyriakis, AG Karra, O Papaioannou, T Solovou, VT Skamnaki, ... Bioorganic & Medicinal Chemistry 28 (1), 115196, 2020 | 7 | 2020 |
Novel diarylamides and diarylureas with N-substitution dependent activity against medulloblastoma C Lawson, TBA Alta, G Moschou, V Skamnaki, TGA Solovou, C Topham, ... European journal of medicinal chemistry 225, 113751, 2021 | 5 | 2021 |
Mutagenesis of a Lotus japonicus GSK3β/Shaggy-like kinase reveals functionally conserved regulatory residues TGA Solovou, C Garagounis, E Kyriakis, C Bobas, GE Papadopoulos, ... Phytochemistry 186, 112707, 2021 | 4 | 2021 |
Biochemical and Structural Studies of LjSK1, a Lotus japonicus GSK3β/SHAGGY-like Kinase, Reveal Its Functional Role TGA Solovou, G Stravodimos, GE Papadopoulos, VT Skamnaki, ... Journal of Agricultural and Food Chemistry 72 (7), 3763-3772, 2024 | | 2024 |
Novel diarylamides and diarylureas with N-substitution dependent activity against medulloblastoma TJ Snape, C Lawson, TBA Alta, G Moschou, V Skamnaki, TGA Solovou, ... Elsevier, 2021 | | 2021 |