MicroRNA-210 controls mitochondrial metabolism during hypoxia by repressing the iron-sulfur cluster assembly proteins ISCU1/2 SY Chan, YY Zhang, C Hemann, CE Mahoney, JL Zweier, J Loscalzo Cell metabolism 10 (4), 273-284, 2009 | 720 | 2009 |
S-glutathionylation uncouples eNOS and regulates its cellular and vascular function CA Chen, TY Wang, S Varadharaj, LA Reyes, C Hemann, MAH Talukder, ... Nature 468 (7327), 1115-1118, 2010 | 637 | 2010 |
Higher blood flow and circulating NO products offset high-altitude hypoxia among Tibetans SC Erzurum, S Ghosh, AJ Janocha, W Xu, S Bauer, NS Bryan, J Tejero, ... Proceedings of the National Academy of Sciences 104 (45), 17593-17598, 2007 | 433 | 2007 |
Rapid kinetic studies link tetrahydrobiopterin radical formation to heme-dioxy reduction and arginine hydroxylation in inducible nitric-oxide synthase CC Wei, ZQ Wang, Q Wang, AL Meade, C Hemann, R Hille, DJ Stuehr Journal of biological chemistry 276 (1), 315-319, 2001 | 169 | 2001 |
Characterization of the mechanism and magnitude of cytoglobin-mediated nitrite reduction and nitric oxide generation under anaerobic conditions H Li, C Hemann, TM Abdelghany, MA El-Mahdy, JL Zweier Journal of Biological Chemistry 287 (43), 36623-36633, 2012 | 148 | 2012 |
Genetic and hypoxic alterations of the micro RNA‐210‐ISCU 1/2 axis promote iron–sulfur deficiency and pulmonary hypertension K White, Y Lu, S Annis, AE Hale, BN Chau, JE Dahlman, C Hemann, ... EMBO molecular medicine 7 (6), 695-713, 2015 | 132 | 2015 |
Peroxynitrite induces destruction of the tetrahydrobiopterin and heme in endothelial nitric oxide synthase: transition from reversible to irreversible enzyme inhibition W Chen, LJ Druhan, CA Chen, C Hemann, YR Chen, V Berka, AL Tsai, ... Biochemistry 49 (14), 3129-3137, 2010 | 124 | 2010 |
A tetrahydrobiopterin radical forms and then becomes reduced during Nω-hydroxyarginine oxidation by nitric-oxide synthase CC Wei, ZQ Wang, C Hemann, R Hille, DJ Stuehr Journal of Biological Chemistry 278 (47), 46668-46673, 2003 | 123 | 2003 |
Hypoxia and reoxygenation induce endothelial nitric oxide synthase uncoupling in endothelial cells through tetrahydrobiopterin depletion and S-glutathionylation F De Pascali, C Hemann, K Samons, CA Chen, JL Zweier Biochemistry 53 (22), 3679-3688, 2014 | 121 | 2014 |
Cytoglobin regulates blood pressure and vascular tone through nitric oxide metabolism in the vascular wall X Liu, MA El-Mahdy, J Boslett, S Varadharaj, C Hemann, TM Abdelghany, ... Nature communications 8 (1), 14807, 2017 | 100 | 2017 |
Iron-sulfur cluster biosynthesis: characterization of Schizosaccharomyces pombe Isa1 G Wu, SS Mansy, C Hemann, R Hille, KK Surerus, J Cowan JBIC Journal of Biological Inorganic Chemistry 7, 526-532, 2002 | 97 | 2002 |
Kinetic and spectroscopic studies of the molybdenum-copper CO dehydrogenase from Oligotropha carboxidovorans B Zhang, CF Hemann, R Hille Journal of Biological Chemistry 285 (17), 12571-12578, 2010 | 94 | 2010 |
Catalytic reduction of a tetrahydrobiopterin radical within nitric-oxide synthase CC Wei, ZQ Wang, J Tejero, YP Yang, C Hemann, R Hille, DJ Stuehr Journal of biological chemistry 283 (17), 11734-11742, 2008 | 87 | 2008 |
Silver-zinc redox-coupled electroceutical wound dressing disrupts bacterial biofilm J Banerjee, PD Ghatak, S Roy, S Khanna, C Hemann, B Deng, A Das, ... PloS one 10 (3), e0119531, 2015 | 85 | 2015 |
The Active Site of Arsenite Oxidase from Alcaligenes f aecalis T Conrads, C Hemann, GN George, IJ Pickering, RC Prince, R Hille Journal of the American Chemical Society 124 (38), 11276-11277, 2002 | 82 | 2002 |
Rubredoxin from the green sulfur bacterium Chlorobium tepidum functions as an electron acceptor for pyruvate ferredoxin oxidoreductase KS Yoon, R Hille, C Hemann, FR Tabita Journal of Biological Chemistry 274 (42), 29772-29778, 1999 | 77 | 1999 |
Stabilization and characterization of a heme-oxy reaction intermediate in inducible nitric-oxide synthase J Tejero, A Biswas, ZQ Wang, RC Page, MM Haque, C Hemann, ... Journal of Biological Chemistry 283 (48), 33498-33507, 2008 | 71 | 2008 |
Redox modulation of endothelial nitric oxide synthase by glutaredoxin-1 through reversible oxidative post-translational modification CA Chen, F De Pascali, A Basye, C Hemann, JL Zweier Biochemistry 52 (38), 6712-6723, 2013 | 70 | 2013 |
Removal of H2O2 and generation of superoxide radical: role of cytochrome c and NADH M Velayutham, C Hemann, JL Zweier Free Radical Biology and Medicine 51 (1), 160-170, 2011 | 70 | 2011 |
Characterization of the function of cytoglobin as an oxygen-dependent regulator of nitric oxide concentration X Liu, D Follmer, JR Zweier, X Huang, C Hemann, K Liu, LJ Druhan, ... Biochemistry 51 (25), 5072-5082, 2012 | 69 | 2012 |