关注
Oscar Vargas-Rodriguez
Oscar Vargas-Rodriguez
UConn Health
在 uchc.edu 的电子邮件经过验证 - 首页
标题
引用次数
引用次数
年份
Upgrading aminoacyl-tRNA synthetases for genetic code expansion
O Vargas-Rodriguez, A Sevostyanova, D Söll, A Crnković
Current opinion in chemical biology 46, 115-122, 2018
1112018
Emergent rules for codon choice elucidated by editing rare arginine codons in Escherichia coli
MG Napolitano, M Landon, CJ Gregg, MJ Lajoie, L Govindarajan, ...
Proceedings of the National Academy of Sciences 113 (38), E5588-E5597, 2016
742016
Exclusive use of trans-editing domains prevents proline mistranslation
O Vargas-Rodriguez, K Musier-Forsyth
Journal of Biological Chemistry 288 (20), 14391-14399, 2013
542013
Double mimicry evades tRNA synthetase editing by toxic vegetable-sourced non-proteinogenic amino acid
Y Song, H Zhou, MN Vo, Y Shi, MH Nawaz, O Vargas-Rodriguez, ...
Nature Communications 8 (1), 2281, 2017
462017
Genetic encoding of three distinct noncanonical amino acids using reprogrammed initiator and nonsense codons
JM Tharp, O Vargas-Rodriguez, A Schepartz, D Soll
ACS chemical biology 16 (4), 766-774, 2021
442021
Engineering posttranslational proofreading to discriminate nonstandard amino acids
AM Kunjapur, DA Stork, E Kuru, O Vargas-Rodriguez, M Landon, D Söll, ...
Proceedings of the National Academy of Sciences 115 (3), 619-624, 2018
432018
Homologous trans-editing factors with broad tRNA specificity prevent mistranslation caused by serine/threonine misactivation
Z Liu*, O Vargas-Rodriguez*, Y Goto, EM Novoa, L Ribas de Pouplana, ...
Proceedings of the National Academy of Sciences 112 (19), 6027-6032, 2015
432015
Distinct tRNA recognition strategies used by a homologous family of editing domains prevent mistranslation
M Das*, O Vargas-Rodriguez*, Y Goto, H Suga, K Musier-Forsyth
Nucleic acids research 42 (6), 3943-3953, 2014
422014
Mechanistic insights into the slow peptide bond formation with D-amino acids in the ribosomal active site
SV Melnikov, NF Khabibullina, E Mairhofer, O Vargas-Rodriguez, ...
Nucleic Acids Research 47 (4), 2089-2100, 2019
362019
Transfer RNAs with novel cloverleaf structures
T Mukai, O Vargas-Rodriguez, M Englert, HJ Tripp, NN Ivanova, ...
Nucleic Acids Research 45 (5), 2776-2785, 2017
352017
The central role of tRNA in genetic code expansion
NM Reynolds, O Vargas-Rodriguez, D Söll, A Crnković
Biochimica et Biophysica Acta (BBA)-General Subjects 1861 (11), 3001-3008, 2017
342017
Ancestral AlaX editing enzymes for control of genetic code fidelity are not tRNA-specific
EM Novoa, O Vargas-Rodriguez, S Lange, Y Goto, H Suga, ...
Journal of Biological Chemistry 290 (16), 10495-10503, 2015
252015
Engineered aminoacyl-tRNA synthetases with improved selectivity toward noncanonical amino acids
HS Kwok, O Vargas-Rodriguez, SV Melnikov, D Söll
ACS chemical biology 14 (4), 603-612, 2019
242019
Conformational and chemical selection by a trans-acting editing domain
EM Danhart, M Bakhtina, WA Cantara, AB Kuzmishin, X Ma, BL Sanford, ...
Proceedings of the National Academy of Sciences 114 (33), E6774-E6783, 2017
222017
A cysteinyl-tRNA synthetase variant confers resistance against selenite toxicity and decreases selenocysteine misincorporation
KS Hoffman*, O Vargas-Rodriguez*, DW Bak, T Mukai, LK Woodward, ...
Journal of Biological Chemistry 294 (34), 12855-12865, 2019
172019
Plasticity and constraints of tRNA aminoacylation define directed evolution of aminoacyl-tRNA synthetases
A Crnković, O Vargas-Rodriguez, D Söll
International journal of molecular sciences 20 (9), 2294, 2019
162019
Effects of heterologous tRNA modifications on the production of proteins containing noncanonical amino acids
A Crnković*, O Vargas-Rodriguez*, A Merkuryev, D Söll
Bioengineering 5 (1), 11, 2018
162018
Bacterial translation machinery for deliberate mistranslation of the genetic code
O Vargas-Rodriguez, AH Badran, KS Hoffman, M Chen, A Crnković, ...
Proceedings of the National Academy of Sciences 118 (35), e2110797118, 2021
142021
Human trans-editing enzyme displays tRNA acceptor-stem specificity and relaxed amino acid selectivity
O Vargas-Rodriguez, M Bakhtina, D McGowan, J Abid, Y Goto, H Suga, ...
Journal of Biological Chemistry 295 (48), 16180-16190, 2020
122020
Uncovering translation roadblocks during the development of a synthetic tRNA
A Prabhakar, N Krahn, J Zhang, O Vargas-Rodriguez, M Krupkin, Z Fu, ...
Nucleic Acids Research 50 (18), 10201-10211, 2022
112022
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