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Els Pardon
Els Pardon
在 vub.ac.be 的电子邮件经过验证
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引用次数
引用次数
年份
Crystal structure of the β2 adrenergic receptor–Gs protein complex
SGF Rasmussen, BT DeVree, Y Zou, AC Kruse, KY Chung, TS Kobilka, ...
Nature 477 (7366), 549-555, 2011
34462011
Structure of a nanobody-stabilized active state of the β2 adrenoceptor
SGF Rasmussen, HJ Choi, JJ Fung, E Pardon, P Casarosa, PS Chae, ...
Nature 469 (7329), 175-180, 2011
19952011
Activation and allosteric modulation of a muscarinic acetylcholine receptor
AC Kruse, AM Ring, A Manglik, J Hu, K Hu, K Eitel, H Hübner, E Pardon, ...
Nature 504 (7478), 101-106, 2013
9572013
A general protocol for the generation of Nanobodies for structural biology
E Pardon, T Laeremans, S Triest, SGF Rasmussen, A Wohlkönig, A Ruf, ...
Nature protocols 9 (3), 674-693, 2014
7482014
GABAA receptor signalling mechanisms revealed by structural pharmacology
S Masiulis, R Desai, T Uchański, I Serna Martin, D Laverty, D Karia, ...
Nature 565 (7740), 454-459, 2019
4952019
Mutations in PMM2, a phosphomannomutase gene on chromosome 16p13 in carbohydrate-deficient glycoprotein type I syndrome (Jaeken syndrome)
G Matthijs, E Schollen, E Pardon, M Veiga-Da-Cunha, J Jaeken, ...
Nature genetics 16 (1), 88-92, 1997
4131997
Structure of the nanobody-stabilized active state of the kappa opioid receptor
T Che, S Majumdar, SA Zaidi, P Ondachi, JD McCorvy, S Wang, ...
Cell 172 (1), 55-67. e15, 2018
3672018
Allosteric nanobodies reveal the dynamic range and diverse mechanisms of G-protein-coupled receptor activation
DP Staus, RT Strachan, A Manglik, B Pani, AW Kahsai, TH Kim, ...
Nature 535 (7612), 448-452, 2016
3332016
Cryo-EM structure of the human α1β3γ2 GABAA receptor in a lipid bilayer
D Laverty, R Desai, T Uchański, S Masiulis, WJ Stec, T Malinauskas, ...
Nature 565 (7740), 516-520, 2019
3062019
Structures of P-glycoprotein reveal its conformational flexibility and an epitope on the nucleotide-binding domain
AB Ward, P Szewczyk, V Grimard, CW Lee, L Martinez, R Doshi, A Caya, ...
Proceedings of the National Academy of Sciences 110 (33), 13386-13391, 2013
2892013
Structural flexibility of the Gαs α-helical domain in the β2-adrenoceptor Gs complex
GH Westfield, SGF Rasmussen, M Su, S Dutta, BT DeVree, KY Chung, ...
Proceedings of the National Academy of Sciences 108 (38), 16086-16091, 2011
2772011
Identification of a universal VHH framework to graft non-canonical antigen-binding loops of camel single-domain antibodies
D Saerens, M Pellis, R Loris, E Pardon, M Dumoulin, A Matagne, L Wyns, ...
Journal of molecular biology 352 (3), 597-607, 2005
2732005
Allosteric coupling from G protein to the agonist-binding pocket in GPCRs
BT DeVree, JP Mahoney, GA Vélez-Ruiz, SGF Rasmussen, AJ Kuszak, ...
Nature 535 (7610), 182-186, 2016
2652016
Structure and flexibility of the endosomal Vps34 complex reveals the basis of its function on membranes
K Rostislavleva, N Soler, Y Ohashi, L Zhang, E Pardon, JE Burke, ...
Science 350 (6257), aac7365, 2015
2532015
The molecular mechanism of transport by the mitochondrial ADP/ATP carrier
JJ Ruprecht, MS King, T Zögg, AA Aleksandrova, E Pardon, PG Crichton, ...
Cell 176 (3), 435-447. e15, 2019
2492019
Crystal structure of the N-terminal domain of the secretin GspD from ETEC determined with the assistance of a nanobody
KV Korotkov, E Pardon, J Steyaert, WGJ Hol
Structure 17 (2), 255-265, 2009
2292009
Structures of β-klotho reveal a ‘zip code’-like mechanism for endocrine FGF signalling
S Lee, J Choi, J Mohanty, LP Sousa, F Tome, E Pardon, J Steyaert, ...
Nature 553 (7689), 501-505, 2018
2112018
Structure and properties of a complex of α-synuclein and a single-domain camelid antibody
EJ De Genst, T Guilliams, J Wellens, EM O'day, CA Waudby, S Meehan, ...
Journal of molecular biology 402 (2), 326-343, 2010
2072010
Crystal structure of a SLC11 (NRAMP) transporter reveals the basis for transition-metal ion transport
IA Ehrnstorfer, ER Geertsma, E Pardon, J Steyaert, R Dutzler
Nature Structural & Molecular Biology 21 (11), 990-996, 2014
2012014
Structural basis for GABAA receptor potentiation by neurosteroids
PS Miller, S Scott, S Masiulis, L De Colibus, E Pardon, J Steyaert, ...
Nature structural & molecular biology 24 (11), 986-992, 2017
1832017
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