Rapid non-uniform adaptation to conformation-specific KRAS (G12C) inhibition JY Xue, Y Zhao, J Aronowitz, TT Mai, A Vides, B Qeriqi, D Kim, C Li, ... Nature 577 (7790), 421-425, 2020 | 403 | 2020 |
Quantitative determinants of aerobic glycolysis identify flux through the enzyme GAPDH as a limiting step AA Shestov, X Liu, Z Ser, AA Cluntun, YP Hung, L Huang, D Kim, A Le, ... elife 3, e03342, 2014 | 328 | 2014 |
The ALS/FTLD associated protein C9orf72 associates with SMCR8 and WDR41 to regulate the autophagy-lysosome pathway PM Sullivan, X Zhou, AM Robins, DH Paushter, D Kim, MB Smolka, F Hu Acta neuropathologica communications 4, 1-16, 2016 | 326 | 2016 |
Diverse alterations associated with resistance to KRAS (G12C) inhibition Y Zhao, YR Murciano-Goroff, JY Xue, A Ang, J Lucas, TT Mai, ... Nature 599 (7886), 679-683, 2021 | 255 | 2021 |
Targeting KRAS (G12C): from inhibitory mechanism to modulation of antitumor effects in patients D Kim, JY Xue, P Lito Cell 183 (4), 850-859, 2020 | 172 | 2020 |
Pan-KRAS inhibitor disables oncogenic signalling and tumour growth D Kim, L Herdeis, D Rudolph, Y Zhao, J Böttcher, A Vides, ... Nature 619 (7968), 160-166, 2023 | 148 | 2023 |
Phosphoproteomics reveals distinct modes of Mec1/ATR signaling during DNA replication FMB de Oliveira, D Kim, JR Cussiol, J Das, MC Jeong, L Doerfler, ... Molecular cell 57 (6), 1124-1132, 2015 | 124 | 2015 |
Progranulin deficiency leads to reduced glucocerebrosidase activity X Zhou, DH Paushter, MD Pagan, D Kim, M Nunez Santos, RL Lieberman, ... PLoS One 14 (7), e0212382, 2019 | 69 | 2019 |
Chemical remodeling of a cellular chaperone to target the active state of mutant KRAS CJ Schulze, KJ Seamon, Y Zhao, YC Yang, J Cregg, D Kim, A Tomlinson, ... Science 381 (6659), 794-799, 2023 | 63 | 2023 |
Low lamin A levels enhance confined cell migration and metastatic capacity in breast cancer ES Bell, P Shah, N Zuela-Sopilniak, D Kim, AA Varlet, JLP Morival, ... Oncogene 41 (36), 4211-4230, 2022 | 62 | 2022 |
ATR-mediated proteome remodeling is a major determinant of homologous recombination capacity in cancer cells D Kim, Y Liu, S Oberly, R Freire, MB Smolka Nucleic acids research 46 (16), 8311-8325, 2018 | 57 | 2018 |
PERK inhibits DNA replication during the Unfolded Protein Response via Claspin and Chk1 E Cabrera, S Hernández-Pérez, S Koundrioukoff, M Debatisse, D Kim, ... Oncogene 36 (5), 678-686, 2017 | 51 | 2017 |
The G protein signaling regulator RGS3 enhances the GTPase activity of KRAS C Li, A Vides, D Kim, JY Xue, Y Zhao, P Lito Science 374 (6564), 197-201, 2021 | 50 | 2021 |
PLEKHA4/kramer attenuates dishevelled ubiquitination to modulate Wnt and planar cell polarity signaling AS Shah, AG Batrouni, D Kim, A Punyala, W Cao, C Han, ML Goldberg, ... Cell reports 27 (7), 2157-2170. e8, 2019 | 34 | 2019 |
Next-generation sequencing enables spatiotemporal resolution of human centromere replication timing DJ Massey, D Kim, KE Brooks, MB Smolka, A Koren Genes 10 (4), 269, 2019 | 24 | 2019 |
Estimating relative changes of metabolic fluxes L Huang, D Kim, X Liu, CR Myers, JW Locasale PLoS Computational Biology 10 (11), e1003958, 2014 | 21 | 2014 |
Glucosylation by the Legionella effector SetA promotes the nuclear localization of the transcription factor TFEB WHJ Beck, D Kim, J Das, H Yu, MB Smolka, Y Mao Iscience 23 (7), 2020 | 20 | 2020 |
Quantitative analysis of DNA damage signaling responses to chemical and genetic perturbations FM Bastos de Oliveira, D Kim, M Lanz, MB Smolka Genome Instability: Methods and Protocols, 645-660, 2018 | 15 | 2018 |
Intrinsic ATR signaling shapes DNA end resection and suppresses toxic DNA-PKcs signaling D Dibitetto, JR Sims, CFR Ascençao, K Feng, D Kim, S Oberly, R Freire, ... NAR cancer 2 (2), zcaa006, 2020 | 14 | 2020 |
Cell density-dependent acetylation of ΔNp63α is associated with p53-dependent cell cycle arrest YS Chae, H Kim, D Kim, H Lee, H Lee FEBS letters 586 (8), 1128-1134, 2012 | 14 | 2012 |