Chalcone: a privileged structure in medicinal chemistry C Zhuang, W Zhang, C Sheng, W Zhang, C Xing, Z Miao Chemical reviews 117 (12), 7762-7810, 2017 | 1254 | 2017 |
Diverse molecular targets for chalcones with varied bioactivities B Zhou, C Xing Medicinal chemistry 5 (8), 388, 2015 | 244 | 2015 |
Structure− activity relationship studies of chalcone leading to 3-hydroxy-4, 3′, 4′, 5′-tetramethoxychalcone and its analogues as potent nuclear factor κB inhibitors and … B Srinivasan, TE Johnson, R Lad, C Xing Journal of medicinal chemistry 52 (22), 7228-7235, 2009 | 223 | 2009 |
A detection system based on giant magnetoresistive sensors and high‐moment magnetic nanoparticles demonstrates zeptomole sensitivity: potential for personalized medicine B Srinivasan, Y Li, Y Jing, YH Xu, X Yao, C Xing, JP Wang Angewandte Chemie International Edition 48 (15), 2764-2767, 2009 | 174 | 2009 |
Rapid identification of Keap1–Nrf2 small-molecule inhibitors through structure-based virtual screening and hit-based substructure search C Zhuang, S Narayanapillai, W Zhang, YY Sham, C Xing Journal of medicinal chemistry 57 (3), 1121-1126, 2014 | 143 | 2014 |
A JNK-mediated autophagy pathway that triggers c-IAP degradation and necroptosis for anticancer chemotherapy W He, Q Wang, B Srinivasan, J Xu, MT Padilla, Z Li, X Wang, Y Liu, X Gou, ... Oncogene 33 (23), 3004-3013, 2014 | 126 | 2014 |
Nanomagnetic competition assay for low-abundance protein biomarker quantification in unprocessed human sera Y Li, B Srinivasan, Y Jing, X Yao, MA Hugger, JP Wang, C Xing Journal of the American Chemical Society 132 (12), 4388-4392, 2010 | 108 | 2010 |
Anti-cancer and other bioactivities of Korean Angelica gigas Nakai (AGN) and its major pyranocoumarin compounds J Zhang, L Li, C Jiang, C Xing, SH Kim, J Lu Anti-Cancer Agents in Medicinal Chemistry (Formerly Current Medicinal …, 2012 | 99 | 2012 |
Inhibitor of apoptosis protein (IAP) antagonists in anticancer agent discovery: Current status and perspectives H Cong, L Xu, Y Wu, Z Qu, T Bian, W Zhang, C Xing, C Zhuang Journal of Medicinal Chemistry 62 (12), 5750-5772, 2019 | 95 | 2019 |
sHA 14-1, a stable and ROS-free antagonist against anti-apoptotic Bcl-2 proteins, bypasses drug resistances and synergizes cancer therapies in human leukemia cell D Tian, SG Das, JM Doshi, J Peng, J Lin, C Xing Cancer letters 259 (2), 198-208, 2008 | 84 | 2008 |
Structure−Activity Relationship and Molecular Mechanisms of Ethyl 2-Amino-4-(2-ethoxy-2-oxoethyl)-6-phenyl-4H-chromene-3-carboxylate (sHA 14-1) and Its … SG Das, JM Doshi, D Tian, SN Addo, B Srinivasan, DL Hermanson, ... Journal of medicinal chemistry 52 (19), 5937-5949, 2009 | 83 | 2009 |
After embedding in membranes antiapoptotic Bcl-XL protein binds both Bcl-2 homology region 3 and helix 1 of proapoptotic Bax protein to inhibit apoptotic mitochondrial … J Ding, BHM Mooers, Z Zhang, J Kale, D Falcone, J McNichol, B Huang, ... Journal of Biological Chemistry 289 (17), 11873-11896, 2014 | 82 | 2014 |
Structure–Activity Relationship and Molecular Mechanisms of Ethyl 2-Amino-6-(3,5-dimethoxyphenyl)-4-(2-ethoxy-2-oxoethyl)-4H-chromene-3-carboxylate … SG Das, B Srinivasan, DL Hermanson, NP Bleeker, JM Doshi, R Tang, ... Journal of medicinal chemistry 54 (16), 5937-5948, 2011 | 68 | 2011 |
A three-layer competition-based giant magnetoresistive assay for direct quantification of endoglin from human urine B Srinivasan, Y Li, Y Jing, C Xing, J Slaton, JP Wang Analytical chemistry 83 (8), 2996-3002, 2011 | 63 | 2011 |
Preparation of penta-O-galloyl-β-d-glucose from tannic acid and plasma pharmacokinetic analyses by liquid–liquid extraction and reverse-phase HPLC L Li, AA Shaik, J Zhang, K Nhkata, L Wang, Y Zhang, C Xing, SH Kim, ... Journal of pharmaceutical and biomedical analysis 54 (3), 545-550, 2011 | 63 | 2011 |
Small molecules inhibiting Keap1–Nrf2 protein–protein interactions: a novel approach to activate Nrf2 function C Zhuang, Z Wu, C Xing, Z Miao MedChemComm 8 (2), 286-294, 2017 | 62 | 2017 |
Dual mechanisms of sHA 14-1 in inducing cell death through endoplasmic reticulum and mitochondria D Hermanson, SN Addo, AA Bajer, JS Marchant, SGK Das, B Srinivasan, ... Molecular pharmacology 76 (3), 667-678, 2009 | 62 | 2009 |
Development of selective inhibitors for anti-apoptotic Bcl-2 proteins from BHI-1 C Xing, L Wang, XH Tang, YY Sham Bioorganic & medicinal chemistry 15 (5), 2167-2176, 2007 | 59 | 2007 |
Kava for the treatment of generalised anxiety disorder (K-GAD): study protocol for a randomised controlled trial KM Savage, CK Stough, GJ Byrne, A Scholey, C Bousman, J Murphy, ... Trials 16, 1-13, 2015 | 58 | 2015 |
Ethyl-2-amino-6-bromo-4-(1-cyano-2-ethoxy-2-oxoethyl)-4H- chromene-3-carboxylate (HA 14-1), a Prototype Small-Molecule Antagonist against Antiapoptotic Bcl … JM Doshi, D Tian, C Xing Molecular pharmaceutics 4 (6), 919-928, 2007 | 58 | 2007 |