| Strategies to address low drug solubility in discovery and development HD Williams, NL Trevaskis, SA Charman, RM Shanker, WN Charman, ... Pharmacological reviews 65 (1), 315-499, 2013 | 1673 | 2013 |
| 50 years of oral lipid-based formulations: provenance, progress and future perspectives OM Feeney, MF Crum, CL McEvoy, NL Trevaskis, HD Williams, ... Advanced drug delivery reviews 101, 167-194, 2016 | 380 | 2016 |
| Toward the establishment of standardized in vitro tests for lipid-based formulations, part 1: method parameterization and comparison of in vitro digestion profiles across a … HD Williams, P Sassene, K Kleberg, JC Bakala-N'Goma, M Calderone, ... Journal of pharmaceutical sciences 101 (9), 3360-3380, 2012 | 270 | 2012 |
| Ionic liquids provide unique opportunities for oral drug delivery: structure optimization and in vivo evidence of utility HD Williams, Y Sahbaz, L Ford, TH Nguyen, PJ Scammells, CJH Porter Chemical Communications 50 (14), 1688-1690, 2014 | 152 | 2014 |
| Lipid digestion as a trigger for supersaturation: evaluation of the impact of supersaturation stabilization on the in vitro and in vivo performance of self-emulsifying drug … MU Anby, HD Williams, M McIntosh, H Benameur, GA Edwards, ... Molecular pharmaceutics 9 (7), 2063-2079, 2012 | 145 | 2012 |
| Toward the Establishment of Standardized in Vitro Tests for Lipid-Based Formulations. 2. The Effect of Bile Salt Concentration and Drug Loading on the Performance of Type I … HD Williams, MU Anby, P Sassene, K Kleberg, JC Bakala-N’Goma, ... Molecular pharmaceutics 9 (11), 3286-3300, 2012 | 143 | 2012 |
| Transformation of poorly water-soluble drugs into lipophilic ionic liquids enhances oral drug exposure from lipid based formulations Y Sahbaz, HD Williams, TH Nguyen, J Saunders, L Ford, SA Charman, ... Molecular pharmaceutics 12 (6), 1980-1991, 2015 | 142 | 2015 |
| In vitro digestion testing of lipid-based delivery systems: calcium ions combine with fatty acids liberated from triglyceride rich lipid solutions to form soaps and reduce the … R Devraj, HD Williams, DB Warren, A Mullertz, CJH Porter, CW Pouton International journal of pharmaceutics 441 (1-2), 323-333, 2013 | 129 | 2013 |
| Toward the establishment of standardized in vitro tests for lipid-based formulations, part 3: understanding supersaturation versus precipitation potential during the in vitro … HD Williams, P Sassene, K Kleberg, M Calderone, A Igonin, E Jule, ... Pharmaceutical research 30, 3059-3076, 2013 | 122 | 2013 |
| Lipid-based formulations and drug supersaturation: harnessing the unique benefits of the lipid digestion/absorption pathway HD Williams, NL Trevaskis, YY Yeap, MU Anby, CW Pouton, CJH Porter Pharmaceutical research 30, 2976-2992, 2013 | 118 | 2013 |
| Incomplete Desorption of Liquid Excipients Reduces the in Vitro and in Vivo Performance of Self-Emulsifying Drug Delivery Systems Solidified by Adsorption onto … M Van Speybroeck, HD Williams, TH Nguyen, MU Anby, CJH Porter, ... Molecular pharmaceutics 9 (9), 2750-2760, 2012 | 99 | 2012 |
| ‘Stealth’lipid-based formulations: Poly (ethylene glycol)-mediated digestion inhibition improves oral bioavailability of a model poorly water soluble drug OM Feeney, HD Williams, CW Pouton, CJH Porter Journal of Controlled Release 192, 219-227, 2014 | 86 | 2014 |
| Toward the Establishment of Standardized In Vitro Tests for Lipid-Based Formulations, Part 6: Effects of Varying Pancreatin and Calcium Levels P Sassene, K Kleberg, HD Williams, JC Bakala-N’Goma, F Carrière, ... The AAPS journal 16, 1344-1357, 2014 | 74 | 2014 |
| A new in vitro lipid digestion – in vivo absorption model to evaluate the mechanisms of drug absorption from lipid-based formulations MF Crum, NL Trevaskis, HD Williams, CW Pouton, CJH Porter Pharmaceutical research 33, 970-982, 2016 | 72 | 2016 |
| Toward the Establishment of Standardized In Vitro Tests for Lipid-Based Formulations. 5. Lipolysis of Representative Formulations by Gastric Lipase JC Bakala-N’Goma, HD Williams, PJ Sassene, K Kleberg, M Calderone, ... Pharmaceutical Research 32, 1279-1287, 2015 | 72 | 2015 |
| Lipid-based formulations solidified via adsorption onto the mesoporous carrier Neusilin® US2: Effect of drug type and formulation composition on in vitro pharmaceutical performance HD Williams, M Van Speybroeck, P Augustijns, CJH Porter Journal of pharmaceutical sciences 103 (6), 1734-1746, 2014 | 68 | 2014 |
| Plain Folk in a Rich Man's War: Class and Dissent in Confederate Georgia HD Williams, TC Williams, D Carlson (No Title), 2002 | 62 | 2002 |
| The extended release properties of HPMC matrices in the presence of dietary sugars HD Williams, R Ward, IJ Hardy, CD Melia Journal of controlled release 138 (3), 251-259, 2009 | 60 | 2009 |
| Ionic liquid forms of weakly acidic drugs in oral lipid formulations: preparation, characterization, in vitro digestion, and in vivo absorption studies Y Sahbaz, TH Nguyen, L Ford, CL McEvoy, HD Williams, PJ Scammells, ... Molecular Pharmaceutics 14 (11), 3669-3683, 2017 | 59 | 2017 |
| Digestion of phospholipids after secretion of bile into the duodenum changes the phase behavior of bile components WA Birru, DB Warren, A Ibrahim, HD Williams, H Benameur, CJH Porter, ... Molecular pharmaceutics 11 (8), 2825-2834, 2014 | 56 | 2014 |
