Guidelines for the use and interpretation of assays for monitoring autophagy (4th edition)1 DJ Klionsky, AK Abdel-Aziz, S Abdelfatah, M Abdellatif, A Abdoli, S Abel, ... autophagy 17 (1), 1-382, 2021 | 13207* | 2021 |
Response to myocardial ischemia/reperfusion injury involves Bnip3 and autophagy A Hamacher-Brady, NR Brady, SE Logue, MR Sayen, M Jinno, ... Cell Death & Differentiation 14 (1), 146-157, 2007 | 724 | 2007 |
Enhancing macroautophagy protects against ischemia/reperfusion injury in cardiac myocytes A Hamacher-Brady, NR Brady, RA Gottlieb Journal of Biological Chemistry 281 (40), 29776-29787, 2006 | 672 | 2006 |
Identification of artesunate as a specific activator of ferroptosis in pancreatic cancer cells N Eling, L Reuter, J Hazin, A Hamacher-Brady, NR Brady Oncoscience 2 (5), 517, 2015 | 493 | 2015 |
Modulation of serines 17 and 24 in the LC3-interacting region of Bnip3 determines pro-survival mitophagy versus apoptosis Y Zhu, S Massen, M Terenzio, V Lang, S Chen-Lindner, R Eils, I Novak, ... Journal of Biological Chemistry 288 (2), 1099-1113, 2013 | 457 | 2013 |
Mitophagy programs: mechanisms and physiological implications of mitochondrial targeting by autophagy A Hamacher-Brady, NR Brady Cellular and molecular life sciences 73, 775-795, 2016 | 422 | 2016 |
Artesunate activates mitochondrial apoptosis in breast cancer cells via iron-catalyzed lysosomal reactive oxygen species production A Hamacher-Brady, HA Stein, S Turschner, I Toegel, R Mora, ... Journal of Biological Chemistry 286 (8), 6587-6601, 2011 | 274 | 2011 |
Phosphorylation of the mitochondrial autophagy receptor Nix enhances its interaction with LC3 proteins VV Rogov, H Suzuki, M Marinković, V Lang, R Kato, M Kawasaki, ... Scientific reports 7 (1), 1131, 2017 | 246 | 2017 |
Histone deacetylase 10 promotes autophagy-mediated cell survival I Oehme, JP Linke, BC Böck, T Milde, M Lodrini, B Hartenstein, I Wiegand, ... Proceedings of the National Academy of Sciences 110 (28), E2592-E2601, 2013 | 221 | 2013 |
A wave of reactive oxygen species (ROS)-induced ROS release in a sea of excitable mitochondria NR Brady, A Hamacher-Brady, HV Westerhoff, RA Gottlieb Antioxidants & redox signaling 8 (9-10), 1651-1665, 2006 | 203 | 2006 |
The interplay between pro-death and pro-survival signaling pathways in myocardial ischemia/reperfusion injury: apoptosis meets autophagy A Hamacher-Brady, NR Brady, RA Gottlieb Cardiovascular Drugs and Therapy 20, 445-462, 2006 | 198 | 2006 |
Loss of C9orf72 enhances autophagic activity via deregulated mTOR and TFEB signaling J Ugolino, YJ Ji, K Conchina, J Chu, RS Nirujogi, A Pandey, NR Brady, ... PLoS genetics 12 (11), e1006443, 2016 | 189 | 2016 |
The autophagic response to nutrient deprivation in the hl‐1 cardiac myocyte is modulated by Bcl‐2 and sarco/endoplasmic reticulum calcium stores NR Brady, A Hamacher‐Brady, H Yuan, RA Gottlieb The FEBS journal 274 (12), 3184-3197, 2007 | 152 | 2007 |
Concurrent detection of autolysosome formation and lysosomal degradation by flow cytometry in a high-content screen for inducers of autophagy P Hundeshagen, A Hamacher-Brady, R Eils, NR Brady BMC biology 9, 1-15, 2011 | 137 | 2011 |
Proapoptotic BCL-2 family members and mitochondrial dysfunction during ischemia/reperfusion injury, a study employing cardiac HL-1 cells and GFP biosensors NR Brady, A Hamacher-Brady, RA Gottlieb Biochimica et Biophysica Acta (BBA)-Bioenergetics 1757 (5-6), 667-678, 2006 | 132 | 2006 |
Listeria monocytogenes virulence factors, including listeriolysin O, are secreted in biologically active extracellular vesicles C Coelho, L Brown, M Maryam, R Vij, DFQ Smith, MC Burnet, JE Kyle, ... Journal of Biological Chemistry 294 (4), 1202-1217, 2019 | 126 | 2019 |
Dengue virus inhibition of autophagic flux and dependency of viral replication on proteasomal degradation of the autophagy receptor p62 P Metz, A Chiramel, L Chatel-Chaix, G Alvisi, P Bankhead, ... Journal of virology 89 (15), 8026-8041, 2015 | 123 | 2015 |
Autophagy as a protective response to Bnip3-mediated apoptotic signaling in the heart A Hamacher-Brady, NR Brady, RA Gottlieb, ÅB Gustafsson Autophagy 2 (4), 307-309, 2006 | 121 | 2006 |
Metabolic programs define dysfunctional immune responses in severe COVID-19 patients EA Thompson, K Cascino, AA Ordonez, W Zhou, A Vaghasia, ... Cell reports 34 (11), 2021 | 106 | 2021 |
Mitochondria form contact sites with the nucleus to couple prosurvival retrograde response R Desai, DA East, L Hardy, D Faccenda, M Rigon, J Crosby, MS Alvarez, ... Science advances 6 (51), eabc9955, 2020 | 104 | 2020 |